CAS: 4261-42-1; 2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-6-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)-4H-Chromen-4-One

该化合物其结构特征为:由富兰肯脊柱组成,附有葡萄糖味,使其成为甘蓝味.Isorientin展示了一系列生物活动,包括抗氧化剂,抗炎和潜在的抗癌特性,这归因于它能够撒冷却自由基和调控各种信号路径.该化合物经常受到研究,以了解其健康利益,并关心药理学和营养学领域.Isorientin在极地溶剂中可溶性,其稳定性可能受到诸如pH和温度等因素的影响.此外,它可能有助于发现植物的颜色和口味特征,使其与烹饪和药学环境相关.

结构式图片

上下游产品

CAS号5447-02-9 3,4-二苄氧基苯甲醛 | CAS号480-66-0 2',4',6'-三羟基苯乙酮 | CAS号65490-09-7 1-[2-羟基-4,6-双(甲... | CAS号39548-86-2 2,4-dihydroxy-6... | CAS号115623-29-5 2-benzyloxy-4,6...

合成工艺路线路线简述

  • 合成目标产物 Homoorientin 主要起始原料 2',4',6'-Trihydroxyacetophenone Monohydrate
  • (文献来源)合成步骤主要原料 2',4',6'-Trihydroxyacetophenone Monohydrate
荭草苷置于盐酸体系中,用 水 作为反应溶剂,化学反应 7.0H,以14.3 Mg的收率获得产物异荭草素
参考文献:金莲花花中的酰化黄酮8-C-葡萄糖苷
标题:金莲花花中的酰化黄酮8-C-葡萄糖苷
摘要:分离出十个新的黄酮8-C-葡萄糖苷,Trollichinensides A-j,在葡萄糖部分的c-2",C-3"或c-6"处取代了各种酰基,并从中分离了13种已知的黄酮.花金莲花.包括NMR和hresims在内的光谱分析导致了这些成分的结构的建立,并且电子圆二色性(ecd)实验被用于确定这些分子中葡萄糖残基的绝对构型.
DOI:10.1016/j.Phytol.2018.04.019

海关参考信息

专利信息


专利号:US-2021315830-A1
优先权日:2018-08-31
标题 :A curcumin loaded stabilized polymeric nanoparticles with increased solubility and photo-stability and a green process for the synthesis thereof
发明人:ACHARYA AMITABHA; KUMARI AVNESH; GULIANI ANIKA; KUMAR SANJAY
权利人:COUNCIL SCIENT IND RES
摘要:The present invention explored PLGA NPs synthesis using plant extracts as surfactants by nanoprecipitation process. PLGA NPs synthesized using Camellia sinensis, Dendrocalamus hamiltonii, Ficus palmata and Rubus ellipticus leaf extracts were further explored for encapsulation, controlled and sustained release of well-known antioxidant molecule, curcumin. This plant extract based nanoprecipitation process for the synthesis of PLGA NPs can be further explored for encapsulation of many other antioxidant molecules of therapeutic importance.

专利号:US-2008233242-A1
优先权日:2003-10-08
标 题:Antioxidant of Bamboo Leaves and Its Uses
发明人:ZHANG YING; WU XIAOQIN; YU ZHUOYU; LUO DINGDING; LU BOYI; ZHANG YU
权利人:ZHANG YING; WU XIAOQIN; YU ZHUOYU; LUO DINGDING; LU BOYI; ZHANG YU
摘要:The present invention discloses the composition of antioxidant of bamboo leaves (AOB) and its use. The purpose of present invention is to provide a new food additive which is natural, nutritional, and muti-functional, and which is of rich resources, safety, good effect, and low cost. AOB is yellow or brown powders or particles obtained from bamboo leaves, wherein the main antioxidative components include flavones, lactones, phenolic acids. AOB can either inhibit lipid autoxidation chain reaction, or chelate transitional metal ions, and can be used as primary and second antioxidant. AOB can eliminate nitrite and inhibit the synthesis of N-nitrosamine, and has anti-bacteria, bacteriostatic, deodorizing, aroma enhancing etc. functions. AOB can be commonly used in oil-containing food, meat product, fishery product, expanded food etc. food systems.

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

专利号:US-2025231101-A1
优先权日:2024-01-11
标 题 :Validation of natural matrices for therapeutic use on humans, animals and plants on bio-physical bases as an alternative to validation through chemically definable substances derived from said matrices by isolation and/or synthesis processes and also as an alternative to products comprising natural matrices validated on the basis of their traditional use
发明人:MERCATI VALENTINO; LUCCI JACOPO
权利人:BIOS THERAPY PHYSIOLOGICAL SYSTEMS FOR HEALTH S P A
摘要:The present invention relates to a new method for assessing acceptability ranges or cut-offs for the compliance validation of batches of products comprising or consisting of one or more natural matrix, wherein said products have an ascertained therapeutic or beneficial effect. The invention also relates to a new process for the compliance validation of one or more batches of said products.

专利号:CN-117701652-A
优先权日:2023-12-15
标 题 :Application of glycosyltransferase GyCGT1 in the synthesis of isoorientin

专利号:WO-2006042625-A2
优先权日:2004-10-15
标 题 :Compositions with inhibitors of the synthesis of prostaglandin and/or of leukotriene in conjunction with stimulators of the release of cutaneous neuromediators
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主要参考文献

1. Ye, T., Su, J., Huang, C., et al. Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells Onco. Targets Ther. 9, 7481-7492 (2016). 2. Anilkumar, K., Reddy, G.V., Azad, R., et al. Evaluation of anti-inflammatory properties of isoorientin isolated from tubers of Pueraria tuberosa Oxid. Med. Cell. Longev. 5498054, (2017). 3. Karaoğlan, E.S., Albayrak, A., Kutlu, Z., et al. Gastroprotective and antioxidant effects of Eremurus spectabilis Bieb. methanol extract and its isolated component isoorientin on indomethacin induced gastric ulcers in rats Acta. Cir. Bras. 33(7), 609-618 (2018).

合成参考文献


参考文献:10.1248/cpb.56.485
摘要:Wang Z, Ma C, Tang S, Xiao H, Kakiuchi N, Kida H, Hattori M. Qualitative and quantitative analysis of Swertia herbs by high performance liquid chromatography-diode array detector-mass spectrometry (HPLC-DAD-MS). Chem Pharm Bull (Tokyo). 2008 Apr;56(4):485–90. doi: 10.1248/cpb.56.485.
参考文献:10.1016/j.ejphar.2022.174748
摘要:Zhang L, Zhu XZ, Badamjav R, Zhang JZ, Kou JP, Yu BY, Li F. Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways. Eur J Pharmacol. 2022 Feb 15;917():174748. doi: 10.1016/j.ejphar.2022.174748.
参考文献:10.1021/jf980264t
摘要:Romani A, Mulinacci N, Pinelli P, Vincieri FF, Cimato A. Polyphenolic content in five tuscany cultivars of Olea europaea L. J Agric Food Chem. 1999 Mar;47(3):964–7. doi: 10.1021/jf980264t.
参考文献:10.1002/pca.778
摘要:Pereira CAM, Yariwake JH, Lanças FM, Wauters J, Tits M, Angenot L. A HPTLC densitometric determination of flavonoids from Passiflora alata , P. edulis , P. incarnata and P. caerulea and comparison with HPLC method. Phytochemical Analysis. 2004 Jul;15(4):241–8. doi: 10.1002/pca.778.
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