CAS: 54923-31-8; 5-Bromo-6-Methylpyridin-2-Ol

相似化合物

374633-33-7 1186637-40-0 865156-59-8

上下游产品

CAS号42753-71-9 2-氨基-5-溴-6-甲基吡啶 | CAS号1824-81-3 2-氨基-6-甲基吡啶 | CAS号3279-76-3 2-羟基-6-甲基吡啶 | CAS号39919-65-8 2,5-二溴-6-甲基吡啶 | CAS号126717-60-0 5-溴-2-苄氧基-6-甲基吡啶 | CAS号126717-59-7 2-甲氧基-5-溴-6-甲基吡啶

5-溴-2-氟-6-甲基吡啶置于盐酸,水体系中,化学反应 2.0H,反应生成 5-溴-6-甲基-2(1H)-吡啶酮
参考文献: Antidiabetic Substituted Heteroaryl Compounds[fr] Composés D'Hétéroaryle Substitué Antidiabétiques
标题: Antidiabetic Substituted Heteroaryl Compounds[fr] Composés D'Hétéroaryle Substitué Antidiabétiques
摘要:本发明涉及一种由公式(i)表示的化合物:以及药学上可接受的盐.公式i的化合物是g蛋白偶联受体40(gpr40)的激动剂,并且可能对由g蛋白偶联受体40介导的疾病的治疗,预防和抑制有用.本发明的化合物可能在治疗2型糖尿病,以及通常与该疾病相关的状况,包括肥胖和脂质紊乱,如混合型或糖尿病性血脂异常,高脂血症,高胆固醇血症和高甘油三酯血症中有用.

专利信息

专利号:US-2025026766-A1
优先权日:2022-01-12
标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors
发明人：LI JING; XU WENQING; WANG ZHIWEI
权利人:BEIGENE LTD
摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.

专利号:WO-2024159285-A1
优先权日:2023-01-30
标题 :Nav1.7- and/or nav1.8-inhibiting aryl pyridine compounds, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
发明人：BARREIRO GABRIELA; SANT’ANA DANILO PEREIRA DE; MONTEIRO JÚLIA LAMMOGLIA; GAMBA LUIS EDUARDO REINA; LIMA LÃ?DIA MOREIRA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA
权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO – UFRJ
摘要:The present invention relates to Nav1.7- and/or Nav1.8-inhibiting aryl pyridine compounds. More specifically, the present invention relates to aryl pyridines comprising formula (I): (I), in which the substituents R1 to R10 are selected independently of the groups defined in the description, as well as to processes for preparing same, compositions comprising at least one of these compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits. The present invention pertains to the fields of medicinal chemistry and organic synthesis, as well as to the treatment of pain-related diseases.

专利号:US-9487523-B2
优先权日:2012-03-14
标题 :Process for making CGRP receptor antagonists
发明人：BELYK KEVIN M; CLEATOR EDWARD; KUO SHEN-CHUN; MALIGRES PETER EMMANUEL; XIANG BANGPING; YASUDA NOBUYOSHI; YIN JIANGUO
权利人:MERCK SHARP & DOHME
摘要:The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.