专利号:US-2022400732-A1 优先权日:2019-03-21 标题:Anti-fructose therapy for colorectal and small intestine cancers 发明人:GONCALVES MARCUS; CANTLEY LEWIS C; YUN JIHYE 权利人:UNIV CORNELL 摘要:As described herein ingestion of high amounts of sugar, especially fructose, can increase the growth of intestinal tumors. Such cancer growth can be inhibited or prevented by limiting the amounts of sugar and amino acids ingested, by inhibiting ketohexokinase (KHK), fructose transport (via GLUT5), fatty acid synthesis (via FASN), phosphoinositide 3-kinases (PI3K), or by limiting amounts of sugar and amino acids ingested while also receiving KHK inhibitors, GLUT5 inhibitors, FASN inhibitors, PI3K inhibitors, or a combination of such inhibitors.
专利号:CN-115894507-B 优先权日:2022-11-01 标 题:Synthesis method and application of (+) -water podocarpine
1: Amo-Navarrete J, García-Oreja S, León-Herce D, Navarro-Pérez D, Lázaro- Martínez JL, Álvaro-Afonso FJ. Cantharidin (1%), podophyllin (5%), and salicylic acid (30%) formulation in recalcitrant plantar warts: Analysis of 48 patients. J Med Virol. 2024 Sep;96(9):e29925. doi: 10.1002/jmv.29925. 12:706. doi: 10.12688/f1000research.134667.2. 4: Thekkayil SSM, Golani M, Mahalakshmi M, Golani D, Kalra TS, Yadav R. Podophyllin Toxicity: Case Report of a Rare Poisoning. J Assoc Physicians India. 2024 Jul;72(7):97-99. doi: 10.59556/japi.72.0406. 35(8):627-634. doi: 10.1177/09564624241246298. Epub 2024 Apr 12. 28(3):253-258. doi: 10.1177/12034754241238012. Epub 2024 Mar 18. 48(1):157-162. doi: 10.1007/s12639-024-01654-6. Epub 2024 Feb 25.
合成参考文献
摘要:Koliadenko VG, Levkovskiĭ NM, Golovchenko DIa, Sologub LV, Mamilos P. [Podophyllin in the treatment of lymphangioma]. Vestn Dermatol Venerol. 1980 Jan;(1):56–7. 参考文献:10.4049/jimmunol.157.8.3499 摘要:Youn BS, Kim KK, Kwon BS. A critical role of Sp1- and Ets-related transcription factors in maintaining CTL-specific expression of the mouse perforin gene. 1996 Oct 15;157(8):3499–509. doi: 10.4049/jimmunol.157.8.3499. 摘要:Pleavin M. The treatment of anogenital warts at home. Nurs Times. 2001 Feb;97(6):37–8. 摘要:French L, Nashelsky J. Clinical inquiries. What is the most effective treatment for external genital warts J Fam Pract. 2002 Apr;51(4):313.