专利号:WO-2004096171-A1 优先权日:2003-04-29 标题 :Skin whitening cosmetic composition comprising the extract of machilus thunbergii and the compounds isolated therefrom 发明人:SON JONG-KEUN; LEE SEUNG-HO; CHANG HYEUN-WOOK 权利人:YEUNGNAM EDUCATIONAL FOUND; SON JONG-KEUN; LEE SEUNG-HO; CHANG HYEUN-WOOK 摘要:The present invention is related to a cosmetic composition comprising the extract of Machilus thunbergii and lignan compounds isolated therefrom having potent inhibitory effect on melanin synthesis. Inventive composition shows the excellent inhibitory activity on cultured B-16 melanoma cell therefore, it can be useful in skin whitening cosmetic composition as an cream, skin, lotion, pack and the like.