CAS: 14763-60-1; 4-(Methylsulfonyl)Phenol

相似化合物

3517-90-6 14763-61-2 14763-64-5

上下游产品

CAS号1073-72-9 4-(甲硫基)苯酚 | CAS号71597-85-8 4-羟基苯硼酸 | CAS号20277-69-4 甲烷亚磺酸钠 | CAS号106-41-2 对溴苯酚 | CAS号540-38-5 4-碘苯酚 | CAS号98546-51-1 4-甲硫基苯硼酸 | CAS号67451-16-5 4-ACETOXYPHENYL... | CAS号455-15-2 4-氟苯基甲基砜 | CAS号50910-13-9 (4-methylsulfan... | CAS号98-57-7 4-氯苯基甲基砜 | CAS号20945-65-7 2-氯-4-(甲基磺酰基)苯酚 | CAS号20951-43-3 2-溴-4-甲基磺酰基苯酚 | CAS号1150100-45-0 2-甲基-6-[4-(甲磺酰基... | CAS号67451-16-5 4-ACETOXYPHENYL... | CAS号632628-02-5 2-羟基-5-(甲磺酰基)苯甲醛

对氟苯甲砜置于硫酸,水,Uranyl(Vi) Acetate Dihydrate体系中,用84 %的收率获得4-甲基磺酰苯酚
参考文献:光铀催化的 C-F 通过水分解活化羟基化
标题:光铀催化的 C-F 通过水分解活化羟基化
摘要:C-F键是碳中心键中最强的共价单键(126 Kcal/mol),其中氟的电负性最高(χ = 4),键长最短(1.38 å),Van最小德瓦尔斯半径( R W = 1.47 å),给激活和转化带来了巨大的挑战.在此,C-F转化是通过光铀催化的未活化芳基氟化物的羟基化实现的,使用水作为羟基源,在环境条件下提供多官能酚.激活的特点是单电子转移(set)/氢原子转移(hat)/氧原子转移(oat)的级联序列,与激发的铀酰阳离子高度集成. *uo 2 2+在温和的光激发下促进水分解,以过氧桥联的方式捕获活性氧以用于关键的 Oat 过程,并通过 Hat 过程释放氢气.
Doi:10.1021/jacs.3C13908

专利信息

专利号:US-6143887-A
优先权日:1998-05-14
标题:Process for the stereoselective synthesis of 16-substituted-4-aza-androstanones
发明人：GRATALE DOMINICK F; TOLMAN RICHARD L; SAHOO SOUMYA P
权利人:MERCK & CO INC
摘要:The novel process of the present invention involves the stereoselective synthesis of certain 16β-substituted 4-aza-5α-androstan-3-ones and the useful intermediates obtained therein.

专利号:US-11566004-B2
优先权日:2018-07-23
标题 :Process for the preparation of bromodomain inhibitor
发明人：TRAVERSE JOHN FITZGERALD; YONG KELVIN HIN-YEONG; FERRETTI ANTONIO CHRISTIAN; ALITE HEKLA; MOSELEY JONATHAN; RUDA ANTONIO MARIA; PRIMER DAVID; PHILP STEVEN
权利人:CELGENE QUANTICEL RES INC
摘要:The present invention provides processes of synthesis and purification of a bromodomain inhibitor, Compound 1, which compound includes crystalline forms, amorphous forms, solvates, and hydrates thereof. Embodiments of the disclosure relate to chemical synthesis routes of Compound 1 that provide a scalable method that results in highly pure final product. A further embodiment relates to methods to isolate the most stable polymorph of Compound 1 by crystallization from formic acid and water.

专利号:WO-2023061999-A1
优先权日:2021-10-12
标 题 :Process for preparing a phenolic hydrocarbon
发明人：CORNELLA JOSEP; LE VAILLANT FRANCK
权利人:STUDIENGESELLSCHAFT KOHLE GGMBH
摘要:The present invention discloses a distinct mode of action of a nickel catalyst to forge C-0 bonds to unlock the mild utilization of N2O as O-atom transfer reagent in the synthesis of complex phenols from the corresponding aryl halides.

专利号:EP-1957644-B1
优先权日:2005-12-01
标 题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:WO-9958551-A1
优先权日:1998-05-14
标 题:Process for the stereoselective synthesis of 16-substituted-4-aza-androstanones

专利号:RU-2033995-C1
优先权日:1990-04-02
标 题 :METHOD OF SYNTHESIS OF SULFONYL-β-D- THIOXYLOSIDE