CAS: 155377-05-2; Methyl 6-(Trifluoromethyl)Picolinate

相似化合物

131747-42-7 131747-65-4 131747-53-0

上下游产品

6-(三氟甲基)吡啶-2-甲酸 6-(Trifluoromethyl)Pyridine-2-Carboxylic Acid 131747-42-7
6-碘吡啶-2-甲酸甲酯 Methyl 6-Iodopyridine-2-Carboxylate 849830-15-5

2-三氟甲基吡啶置于正丁基锂,乙酰氯体系中,用 乙醚,正己烷 用作溶剂,化学反应生成6-三氟甲基吡啶-2-甲酸甲酯
参考文献:Combination Therapy For Treating Malignancies
标题:Combination Therapy For Treating Malignancies
摘要:提供了一种治疗携带idh2突变的aml患者的方法和组合物,使用突变idh2酶抑制剂和aml诱导和巩固疗法的组合.

专利信息

专利号:US-9549917-B2
优先权日:2011-09-08
标 题 :Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
发明人：MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; LAI ZHONG; DANG QUN; ZORN NICOLAS
权利人:MCCOMAS CASEY C; LIVERTON NIGEL J; HABERMANN JOERG; KOCH UWE; NARJES FRANK; LI PENG; PENG XUANJIA; SOLL RICHARD; WU HAO; PALANI ANANDAN; DAI XING; LIU HONG; HE SHUWEN; LAI ZHONG; DANG QUN; ZORN NICOLAS; MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:EP-3686190-A1
优先权日:2013-07-11
标 题 :Synthesis of therapeutically active compounds

专利号:WO-2023134686-A1
优先权日:2022-01-11
标题:Preparation method for 1,3,5-triazine derivative
发明人：HUANG TICONG; WU XIAOLEI; WANG SHANG; ZANG HAISHAN; QIN ZHIDONG; ZHANG HONGYING; CAI YAO; ZHAO RUI; LIU FEI
权利人:CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD
摘要:The present invention relates to the field of drug synthesis, particularly, to a preparation method for a 1,3,5-triazine derivative, more particularly, to a preparation method for 4-(tert-butoxyamino)-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazine-2-amine. The preparation method has the advantages of short route, simple operation, and high yield, and is more suitable for use in industrial production.