CAS: 127946-77-4; 1-Amino-1-Cyclopropanecarbonitrile Hydrochloride

相似化合物

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上下游产品

CAS号89985-88-6 1-[(二苯基亚甲基)氨基]环... | CAS号68781-13-5 1-氨基环丙烷羧酸盐酸盐

1-(二苯亚甲基氨基)环丙烷-1-甲腈置于盐酸,水体系中,用 乙醚 用作溶剂,化学反应 15.0H,反应生成1-氨基-1-环丙基腈盐酸盐
参考文献: Di-Fluoro Containing Compounds As Cysteine Protease Inhibitors[fr] Composés Contenant Un Di-Fluoro En Tant Qu'Inhibiteurs De Cystéine Protéase
标题: Di-Fluoro Containing Compounds As Cysteine Protease Inhibitors[fr] Composés Contenant Un Di-Fluoro En Tant Qu'Inhibiteurs De Cystéine Protéase
摘要:本发明涉及一种抑制半胱氨酸蛋白酶的化合物,特别是半胱氨酸蛋白酶b,K,L,F和s,因此可用于治疗由这些蛋白酶介导的疾病.本发明涉及包含这些化合物的药物组合物以及其制备方法.

专利信息

专利号:WO-2016095879-A1
优先权日:2014-12-19
标 题 :Preparation of a highly pure intermediate for the synthesis of odanacatib
发明人：BABIAK PETER; ZEZULA JOSEF
权利人:ZENTIVA KS
摘要:A process for producing (S)-2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-N- (1-cyanocyclopropyl)-4-fluoro-4-methylpentanamide of formula 1 by reaction of the acid or its salts of formula 3 with the compound of formula 4, the reaction being performed in a solvent in the presence of the n-propanephosphonic acid anhydride of formula 5 and a base.

专利号:CZ-2014941-A3
优先权日:2014-12-19
标 题 :Preparation of a highly pure intermediate for Odanacatib synthesis

专利号:EP-2118111-B1
优先权日:2007-02-06
标题 :2-amin0-5, 7-dihydr0-6h- pyrrolo [3, 4-d] pyrimidine derivatives as hsp-90 inhibitors for treating cancer
发明人：BENNETT MICHAEL JOHN; ZEHNDER LUKE RAYMOND; NINKOVIC SACHA; KUNG PEI-PEI; MENG JERRY JIALUN; HUANG BUWEN
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, their synthesis, and their use as HSP-90 inhibitors.