CAS: 13959-02-9; 3-Bromoisonicotinic Acid

相似化合物

13958-98-0 146679-66-5 70201-43-3

上下游产品

CAS号626-55-1 3-溴吡啶 | CAS号124-38-9 二氧化碳 | CAS号3430-22-6 4-甲基-3-溴吡啶 | CAS号71541-34-9 3-bromoisonicot... | CAS号3034-31-9 N-苯基异烟酰胺 | CAS号76006-17-2 1H-吡唑并[3,4-c]吡啶-3-胺 | CAS号59786-31-1 3-溴异烟酸甲酯 | CAS号146679-66-5 3-溴吡啶-4-甲醇 | CAS号13958-98-0 3-溴-4-氰基吡啶 | CAS号13959-01-8 3-溴异烟酸乙酯 | CAS号13958-99-1 3-溴吡啶-4-酰胺 | CAS号909532-61-2 3-bromo-N-metho...

异烟酸置于溴体系中,用 甲醇 用作溶剂,化学反应 5.0H,以96.3%的收率获得3-溴异烟酸
参考文献:一种3-氨基异烟酸甲酯的高收率合成方法
标题:一种3-氨基异烟酸甲酯的高收率合成方法
摘要:本发明属于化学制药领域,具体公开一种3‑氨基异烟酸甲酯的高收率合成方法,以4‑吡啶羧酸为原料,经溴化,氨化,酯化得到所述3‑氨基异烟酸甲酯.本发明所述3‑氨基异烟酸甲酯的高收率合成方法,反应条件温和,总收率高,3‑溴‑4‑吡啶羧酸反应废弃滤液可以反复套用,提高原料的利用率,减少资源浪费,最大限度地降低整体工艺的成产成本,具有极高的应用.

专利信息

专利号:US-2010004245-A1
优先权日:2006-10-20
标 题:Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：OBALLA RENATA M; DESCHENES DENIS; GAGNON MARC; LEBLANC YVES; POWELL DAVID; RAMTOHUL YEEMAN K
权利人:MERCK FROSST CANADA LTD
摘要:Azacycloalkane derivatives of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.

专利号:CN-111100068-A
优先权日:2019-12-29
标 题 :A kind of method for fast and efficient synthesis of methyl 3-aminoisonicotinate

专利号:RU-1826973-C
优先权日:1988-11-14
标 题:Method of synthesis of ethylene copolymer with butene-1

专利号:CN-109336802-B
优先权日:2018-11-20
标题:Synthesis method of diacyl peroxide

专利号:CN-111018775-A
优先权日:2019-12-29
标 题:A kind of high-yield synthesis method of methyl 3-aminoisonicotinate