CAS: 158669-26-2; 4-Iodo-2-Methoxynicotinaldehyde

相似化合物

726206-55-9 1227515-22-1 71255-09-9

上下游产品

CAS号1628-89-3 2-甲氧基吡啶 | CAS号105669-53-2 N-(2-二甲氨基乙烷)-N-甲基甲酰胺 | CAS号124-41-4 甲醇钠 | CAS号113975-22-7 2-氟-3-碘吡啶 | CAS号109-94-4 甲酸乙酯 | CAS号1634-04-4 甲基叔丁基醚 | CAS号726206-53-7 1,2-二氢-4-碘-2-氧代... | CAS号726206-55-9 4-碘-2-甲氧基烟酸

N-Ethoxyethyl-N-Methylformamide置于叔丁基锂,正丁基锂,水,碘,Sodium Sulfite体系中,用 四氢呋喃,正戊烷 用作溶剂,化学反应 1.5H,以54%的收率获得4-碘-2-甲氧基吡啶-3-甲醛
参考文献:Ep1900740
标题:Ep1900740

专利信息

专利号:US-6723853-B2
优先权日:2001-08-27
标 题 :Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
发明人：CURRAN DENNIS P; GABARDA ANA E
权利人:UNIV PITTSBURGH
摘要:A method of synthesizing a compound having the formula: n from a compound having the formula: n wherein R 1 is hydrogen, fluorine, chlorine or SiR 5 R 6 R 7 , wherein R 5 , R 6 , and R 7 are independently the same or different an alkyl group or an aryl group, R 2 is an alkyl group, R 3 is a protecting group, R 4 is an alkyl group, an allyl group, a propargyl group —CO 2 H, or a benzyl group, R 8 is —CO 2 R 10 , wherein R 10 is an alkyl group or an aryl group, X 1 is OH and X 2 is H, includes the step of exposing compound (III) to at least one of an organic acid or an inorganic acid. A compound has the general formula (III).

专利号:US-2003073840-A1
优先权日:2001-08-27
标 题 :Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins

专利号:WO-03018559-A2
优先权日:2001-08-27
标 题 :Intermediates and preparation thereof for the enantioselective synthesis of (20r) homocamptothecins

专利号:US-8466287-B2
优先权日:2005-06-09
标题 :Process for producing tricyclic ketone
发明人：NISHIYAMA HIROYUKI; SAWADA SEIGO
权利人:NISHIYAMA HIROYUKI; SAWADA SEIGO; YAKULT HONSHA KK
摘要:In order to efficiently supply CPT, which is a starting compound of irinotecan hydrochloride and a variety of camptothecin derivatives, by a practical total synthesis, the invention provides a means of efficiently preparing a tricyclic ketone that corresponds to a CDE ring moiety of a camptothecin (CPT) skeleton.