CAS: 27992-32-1; 2-Bromo-6-Hydroxypyridine

相似化合物

40473-07-2 36953-37-4 1214345-40-0

上下游产品

CAS号626-05-1 2,6-二溴吡啶 | CAS号949160-14-9 2-溴-6-叔丁氧基吡啶 | CAS号19798-81-3 2-溴-6-氨基吡啶 | CAS号865-47-4 叔丁醇钾 | CAS号27992-32-1 2-溴-6-羟基吡啶 | CAS号40473-07-2 2-溴-6-甲氧基吡啶 | CAS号27992-32-1 2-溴-6-羟基吡啶 | CAS号117068-71-0 2-溴-6-苄氧基吡啶 | CAS号873383-11-0 6-溴-1-甲基吡啶-2(1H)-酮

Potassium 6-Bromopyridin-2-Yltrifluoroborate置于hydrazine Hydrate,Caesium Carbonate体系中,化学反应 8.0H,以99%的收率获得2-溴-6-羟基吡啶
参考文献:一种催化氧化芳硼类化合物制备酚的方法
标题:一种催化氧化芳硼类化合物制备酚的方法
摘要:本发明公开了一种催化氧化芳硼类化合物合成酚类化合物的方法,在溶剂醇或醇的水溶液中,在碱的作用下,加入水合肼或肼类化合物催化剂,催化氧化芳硼类化合物直接制备酚类化合物.本发明的制备酚类化合物的方法,催化剂是廉价的水合肼或肼类化合物,氧化剂为常压下的空气或氧气,反应无需金属催化剂且活性好,底物来源广泛且稳定,底物敏感官能团相容性好且适用范围广.在优化的反应条件之下,目标产品分离收率高达99%.

专利信息

专利号:US-6376676-B1
优先权日:1993-06-30
标题 :Intermediates in the synthesis of (±)-camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; LIU HUI
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of novel intermediates in the synthesis of (±)-camptothecin and related compounds. The present synthesis scheme includes a novel 4+1 radical annulation followed by another cyclization to simultaneously assemble rings B and C of the camptothecin compound. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-6252079-B1
优先权日:1993-06-30
标 题 :Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; BOM DAVID
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of irinotecan and derivative compounds which comprises of a novel 4+1 radical annulation wherein the precursoris reacted with an aryl isonitrile having the formulawherein X is Br or I, and R4 is an alkyl group, an allyl group, a propargyl group or a benzyl group, and R16 is H, a C1-C6 alkoxy group, agroup wherein p is an integer between 4 and 12, or a C1-C12 acyclic dialkylamino group. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-6982333-B2
优先权日:1993-06-30
标 题:Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; JOSIEN HUBERT; KO SUNG BO
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of camptothecin and related compounds which consists of a novel 4+1 radical annulation. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-2004063947-A1
优先权日:1993-06-30
标 题:Novel intermediates in the synthesis of camptothecin and related compounds and synthesis thereof

专利号:US-6211371-B1
优先权日:1993-06-30
标 题:Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof

专利号:US-6239278-B1
优先权日:1993-06-30
标 题 :Intermediates in the synthesis of (±)-camptothecin and related compounds and synthesis thereof