CAS: 156-28-5; 2-Phenylethylamine Hydrochloride

该化合物是一种有机化合物,其特征是其有矿功能组和芳香结构;它是在水和酒精中可溶解的白到白的晶状结晶固体,可溶于水和酒精,适合研究和工业的各种应用;该化合物以其作为...

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methanol Nα-diphenylphosphinyl-2-phenylethylamine N-(2-phenylethyl)-P,P-dimethylphosphinamide N-(2-phenylethyl)-P,P-diethylphosphinamide N-(2-phenylethyl)pyridine-3-carboxamide phenethyl is°Cyanate 1,3,5-triphenylethyl-1,3,5-triazacyclohexane 3-(phenethylamino-methylene)-indolin-2-one

合成工艺路线路线简述

  • 合成目标产物 2-Phenylethylamine Hydrochloride 主要起始原料 L-Phenylalanine
  • (文献来源)合成步骤主要原料 L-Phenylalanine
β-硝基苯乙烷置于c36H56Cl3Crn2O,Magnesium,频那醇硼烷,盐酸体系中,用 四氢呋喃,水,乙酸乙酯 用作溶剂,化学反应 24.0H,以83%的收率获得2-苯乙胺盐酸盐
参考文献:用铬催化的环状(烷基)(氨基)卡宾配体促进的硝基脱氧硼氢化反应:范围,机制和应用
标题:用铬催化的环状(烷基)(氨基)卡宾配体促进的硝基脱氧硼氢化反应:范围,机制和应用
摘要:利用 N-杂环卡宾作为非无害配体促进转化的过渡金属催化尚未得到很好的研究.我们在这里报告了具有成本效益的铬催化的环状(烷基)(氨基)卡宾(caac)配体促进的硝基脱氧硼氢化反应.使用 1 Mol % 的 Caac-Cr 预催化剂,将 Hbpin 添加到硝基支架上会导致脱氧,从而保留各种可还原的官能团和敏感基团对硼氢化的相容性,从而提供一种温和,化学选择性和易于形成的策略苯胺,以及杂芳基和脂肪胺衍生物,具有广泛的范围和特别高的转换数(高达 1.8 x 106).基于理论计算的机械研究,表明caac配体在促进hbpin氢化物极性反转中起重要作用;它用作 H 穿梭以促进脱氧硼氢化.通过这种策略制备的几种市售药物突出了其在药物化学中的潜在应用.
Doi:10.1021/jacs.0C12318

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专利信息


专利号:US-9181237-B2
优先权日:2013-10-04
标 题 :Substituted berbines and their synthesis
发明人:GROTE CHRISTOPHER W
权利人:MALLINCKRODT LLC
摘要:The present invention provides substituted berbines, processes for the synthesis of substituted berbine compounds, as well as intermediates used in the synthesis of substituted berbine compounds. Also provided are methods for using the substituted berbines to inhibit cancer cell growth.

专利号:US-2016122450-A1
优先权日:2013-05-08
标题:Synthesis of a substituted furan
发明人:ZHANG YUGEN; TEONG SIEW PING; YI GUANGSHUN
权利人:AGENCY SCIENCE TECH & RES
摘要:The present invention provides a polymer comprising an aliphatic backbone having a plurality of aromatic rings bonded thereon, said plurality of aromatic rings comprising a first aromatic ring type that has an alkyl halide group substitution on the aromatic ring and a second aromatic ring type that has an optionally substituted ammonium halide group substitution on the aromatic ring. The present invention also provides a method for making an optionally substituted furan, the method comprising the step of subjecting a sugar to a dehydration reaction in the presence of a catalyst comprising said polymer.

专利号:US-2024324437-A1
优先权日:2023-03-22
标题 :Tunable polymer transport materials for application in perovskite solar cells
发明人:SELLINGER ALAN; ASTRIDGE DANIEL; LEVIN JACOB
权利人:COLORADO SCHOOL OF MINES
摘要:Polymer transport materials for application in perovskite solar cells capable of being tuned or manipulated to achieve desired properties, are provided herein. The present disclosure is directed to methods, systems, and compositions for achieving polymer transport materials (i.e., hole transport materials (HTMs)) with desirable properties such as solution processability, energy level tuning (i.e., adjusting), high thermal properties, tunable (i.e., adjustable) wettability, and perovskite defect passivation. In some aspects of the present disclosure, the synthesis of such HTMs may be implemented via relatively simple and inexpensive processes.

专利号:WO-2015170346-A1
优先权日:2014-05-09
标 题 :A process for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine its enantiomers
发明人:MUTHUKRISHNAN MURUGAN; RAMADOSS VELAYUDHAM; NALLA VISWANADH
权利人:COUNCIL SCIENT IND RES
摘要:The present invention discloses a process for synthesis of Lorcaserin and its analogues using epoxide/chiral epoxide.

专利号:US-2009275727-A1
优先权日:1998-03-24
标题:Peptide turn mimetics
发明人:CASSIDY PETER J; ALEWOOD PAUL FRANCIS; VERNALL ANDREA JOY
权利人:MIMETICA PTY LTD
摘要:This invention provides novel compounds useful for the synthesis of peptide mimetics, and describes the use of these compounds for the synthesis of novel reverse turn mimetics. The reverse turn mimetics of the invention have the general structure X wherein the variables are as defined herein.

专利号:EP-3567040-B1
优先权日:2013-06-24
标 题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines
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合成参考文献


摘要:Shimizu, T., Science of Synthesis Knowledge Updates, (2011) 1, 494.
摘要:Journal of Pharmacology and Experimental Therapeutics., 8(126), 1916
摘要:Russian Pharmacology and Toxicology, 39(209), 1976
摘要:Journal of Pharmacology and Experimental Therapeutics., 71(62), 1941
摘要:Journal of Pharmacology and Experimental Therapeutics., 36(363), 1929
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