CAS: 99-52-5; 2-Methyl-4-Nitroaniline

上下游产品

CAS号95-53-4 邻甲苯胺 | CAS号99-08-1 3-硝基甲苯 | CAS号120-66-1 乙酰邻甲苯胺 | CAS号14150-94-8 1-甲基-3,5-二硝基-1H... | CAS号78-93-3 甲乙酮 | CAS号619-15-8 2,5-二硝基甲苯 | CAS号97-15-4 4-methyl-N-(2-m... | CAS号36164-91-7 N-(3-methyl-4-n... | CAS号80-28-4 4-甲基-N-(2-甲基苯基)苯磺酰胺 | CAS号10589-64-7 4-Chloro-N-(2-m... | CAS号104478-99-1 N-(4-氨基-2-甲基苯基)苯甲酰胺 | CAS号106877-31-0 3-甲基-4-三氟甲基苯胺 | CAS号56309-59-2 2-甲基-4-异氰酸硝基苯 | CAS号329944-72-1 3-溴-5-氯甲苯 | CAS号42860-02-6 3-溴-5-氯苯甲酸 | CAS号14303-59-4 4-amino-N-(4-am... | CAS号21320-90-1 2-甲基-4-硝基苯-1-磺酰氯 | CAS号22952-19-8 Benzenesulfonam... | CAS号21900-27-6 3-Bromo-5-chlor...

2,5-二硝基甲苯置于铁粉,溶剂黄146,Tin(Ll) Chloride,盐酸体系中,化学反应 1.33H,反应生成 4-硝基-2-甲苯胺
参考文献:一种2-甲基-4-硝基苯甲酸的合成方法
标题:一种2-甲基-4-硝基苯甲酸的合成方法
摘要:本发明公开了一种2-甲基-4-硝基苯甲酸的合成方法,属于化学合成技术领域.本发明是以甲苯为原料,加入浓硝酸和浓硫酸混合而成的反应液混合,用氢氧化钠溶液洗涤后,与二氯化锡,铁粉,冰醋酸反应,再滴加盐酸混合得2-氨基-5-硝基甲苯,再与乙酸和浓硫酸混合反应,在氧化剂过硼酸钠的氧化后,冰水降温,去离子水洗涤,再在氧化剂高锰酸钾的在此氧化作用下,与盐酸混合反应,然后静置,抽滤,干燥制得.本发明的有益效果是:该方法合成过程简单,成本低,副产物少;所得产品产率高达95%以上,纯度高达99%以上.

专利信息

专利号:US-2008146772-A1
优先权日:2006-11-02
标题 :Materials and methods for co-crystal controlled solid-state synthesis of imides and imines
发明人：ZAWOROTKO MICHAEL J; CHENEY MIRANDA L
权利人:UNIV SOUTH FLORIDA
摘要:The subject invention pertains to methods for solid-state synthesis of imides and imines using co-crystals. The co-crystal formers utilized are substrates of condensation reactions and co-crystals can be obtained in high yield via methods such as slurrying, solvent evaporation, solvent crystallization, treatment with supercritical fluid(s), melting plus crystallization, slurry conversion, grinding of solids, blending of powders, heating of solids, solvent-drop grinding, or grinding plus melting.

专利号:US-2004044225-A1
优先权日:2001-06-01
标 题:Chiral and achiral synthesis of 2-acyl substituted chromanes and their derivatives
发明人：KANTER JAMES; MARLOWE CHARLES; PANDEY ANJALI; MULLINS JOHN J G; SCARBOROUGH ROBERT; BUTKE GREG; JACOBSON BARRY; WALKER DEREK
摘要:Disclosed are processes for producing a (2S) or (2R) 4-oxo-chroman-2-yl acyl compounds and chroman-2-yl acyl compounds, esters or amides thereof as well as derivatives thereof. Such processes may involve chiral synthesis or achiral synthesis, preferably coupled with a resolution procedure. Such compounds, particularly (2S) or (2R) acetic acid esters, are useful intermedates for producing platelet aggregation inhibitors and/or are themselves potent platelet aggregation inhibitors. Further disclosed are processes for making derivatives of such substantially pure, or enhanced compositions of single (2R) or (2S) enantiomer intermediates or processes for producing final products or salts from such desired enantiomers.

专利号:US-4897484-A
优先权日:1986-12-19
标题 :Process for the preparation of substituted pyridines
发明人：WEIS CLAUS D; SUTTER PETER
权利人:CIBA GEIGY CORP
摘要:A process is described for the preparation of compounds of the formula (1) in which R and X are as defined in claim 1. The compounds of the formula (1) are valuable intermediates in the synthesis of triarylmethane dyes and triarylmethanelactones.

专利号:US-6069277-A
优先权日:1995-05-12
标 题 :Amination of electrophilic aromatic compounds by vicarious nucleophilic substitution
发明人：MITCHELL ALEXANDER R; PAGORIA PHILIP F; SCHMIDT ROBERT D
权利人:UNIV CALIFORNIA
摘要:The present invention relates to a process to aminate electrophilic aromatic compounds by vicarious nucleophilic substitution of hydrogen using quaternary hydrazinium salts. The use of trialkylhydrazinium halide, e.g., trimethylhydrazinium iodide, as well as hydroxylamine, alkoxylamines, and 4-amino-1,2,4-triazole to produce aminated aromatic structures, such as 1,3-diamino-2,4,6-trinitrobenzene (DATB), 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) and 3,5-diamino-2,4,6-trinitrotoluene (DATNT), is described. DATB and TATB are useful insensitive high explosives. TATB is also used for the preparation of benzenehexamine, a starting material for the synthesis of novel materials (optical imaging devices, liquid crystals, ferromagnetic compounds).

专利号:US-6541653-B2
优先权日:2001-04-26
标题 :Synthesis of carbamate through low pressure heterogeneous oxidative carbonylation of amines
发明人：CHUANG STEVEN S C; CHI YAWU; CHEN BEI; TOOCHINDA PISANU
摘要:The process disclosed herein satisfies the need in the art for an industrially viable oxidative carbonylation catalytic system, and is capable of producing carbamates at a significantly higher rate than those processes reported in journal and patent literature. This reaction process takes place via a reaction mechanism that does not involve drastic conditions. Specifically, the catalytic system of the present invention employs Group VIII metal catalysts and/or copper-based catalysts with halide promoters to produce carbamates through heterogeneous oxidative carbonylation at atmospheric pressure and relatively non-drastic temperatures in a gas-solid carbonylation process.

专利号:US-2002183541-A1
优先权日:2001-04-26
标题:Synthesis of carbamate through low pressure heterogeneous oxidative carbonylation of amines