CAS: 54863-37-5; 3-Methanesulfonylpropanenitrile

上下游产品

3-(Methylsulfinyl)Propanenitrile 74338-76-4

L-蛋氨酸置于2Ho(1-)*0.04No3(1-)*0.14Co3(2-)*0.64Ni(2+)*0.36Al(3+)*0.02O4W(2-),双氧水,溴化铵体系中,用 甲醇,水 作为反应溶剂,以72%的收率获得产物3-(甲基磺酰基)丙腈
参考文献:氨基酸非均相催化氧化脱羧的生物基腈
标题:氨基酸非均相催化氧化脱羧的生物基腈
摘要:在水溶液中,通过催化卤化原位卤化物,使用在[ni,Al]层状双氢氧化物(ldh),Nh 4 Br和H2O 2上交换的钨酸盐,将氨基酸氧化成腈作为末端氧化剂.反应物和ldh催化剂之间的邻近效应促进了卤化物的氧化和氧化的脱羧.各种氨基酸的转化率很高,通常> 90%.腈的选择性非常好,经过适当的中和后,该体系可与酰胺,醇,特别是羧酸,胺和胍官能团相容.这种非均相催化系统已成功应用于将淀粉工业中富含蛋白质的副产物转化为有用的生物基含氮化学品.
DOI:10.1002/cssc.201402801

专利信息

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:EP-0040896-B1
优先权日:1978-08-22
标题:Synthesis of amides

专利号:EP-0008532-A1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0040896-A2
优先权日:1978-08-22
标 题 :Synthesis of amides

专利号:CN-106866515-A
优先权日:2017-02-10
标题:A kind of sulfonyl pyridine derivative and its synthesis method