CAS: 10236-58-5; (R)-2-Amino-3-Hydroselenopropanoic Acid

上下游产品

L-硒代胱胺基乙酸 Seleno-L-Cystine 29621-88-3

(2R)-2-Amino-3-[(4,5-Dimethoxy-2-Nitrophenyl)Methylselanyl]Propanoic Acid 反应生成硒代-L-半胱氨酸
参考文献:通过光编码的硒代半胱氨酸的遗传密码扩展产生重组哺乳动物硒代蛋白.
标题:通过光编码的硒代半胱氨酸的遗传密码扩展产生重组哺乳动物硒代蛋白.
摘要:硒蛋白含有氨基酸硒代半胱氨酸(sec),存在于生活的所有领域.人们对许多硒蛋白的功能了解甚少,部分原因是难以生产用于细胞生物学评估的重组硒蛋白.内源性哺乳动物硒蛋白是通过非规范的翻译机制产生的,该机制需要抑制uga终止密码子和mrna 3'非翻译区中的sec插入序列(secis)元件.在这里,重组硒蛋白通过遗传密码扩展在哺乳动物细胞中产生,从而避免了对secis元素和硒可用性的需求.工程化的正交ê.大肠杆菌亮氨酰-Trna合成酶/ Trna对用于在uag琥珀色终止密码子处掺入光笼sec(dmnb-Sec).Dmnb-Sec已成功整合到gfp中,并且未通过活细胞辐照而解笼.此外,Dmnb-Sec用于生成天然硒蛋白蛋氨酸-R-亚砜还原酶b1(msrb1).重要的是,Msrb1被显示为解开后具有催化活性,构成了在哺乳动物系统中首次使用遗传密码扩展来生成功能性硒蛋白.将sec直接特异地引入哺乳动物
Doi:10.1021/acschembio.0C00147

专利信息

专利号:WO-2023233371-A1
优先权日:2022-06-03
标 题:A continuous flow process for synthesis of organic azides
发明人：GNANAPRAKASAM BOOPATHY; PANDEY AKANKSHA M; MONDAL SHANKHAJIT
权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES PUNE IISER PUNE
摘要:The present disclosure relates generally to the field of synthetic organic chemistry. More specifically, the disclosure is directed to a continuous flow process for synthesis of azides from alcohols and peroxides, wherein the process comprises azidation with trimethylsilyl azide and a catalyst Amberlyst-15. It is a non-hazardous, mild and controlled reaction giving good yields of azides. The azides can be further employed for synthesis of medicinally and industrially useful chemicals.

专利号:WO-2025062384-A2
优先权日:2023-09-23
标题 :A method for synthesis of metal halide perovskite (cspbbr3) nano/microcrystals
发明人：M A GOKUL; RAHMAN ATIKUR
权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES PUNE IISER PUNE
摘要:The present invention relates to metal halide perovskite (CsPbBr3) nano/microcrystals. Specifically, the present invention relates to a method for the synthesis of metal halide perovskite (CsPbBr3) nano/microcrystals. The present invention uses an easy, scalable low temperature growth of metal halide nanoparticles like CsPbBr3. The method uses a clever play on the solubility and ion exchange mechanism to precipitate nano and microcrystals of metal halide perovskites. The synthesis resulted in stable perovskite crystals with high photo- luminescence, ultralow dark current and control over their morphology. The combination of ultralow dark current, high responsivity, exceptional detectivity, and broad-band photon detection capabilities makes these crystals an excellent choice for upcoming sensors and detector technologies.

专利号:US-2008287649-A1
优先权日:2006-12-29
标 题 :Methods for the synthesis of cyclic peptides
发明人：CHEN LIN; HAN YEUN-KWEI; ROBERTS CHRISTOPHER R
权利人:CHEN LIN; HAN YEUN-KWEI; ROBERTS CHRISTOPHER R
摘要:Methods for the synthesis of cyclic peptides are provided, as well as novel dipeptide compounds. The methods include the solid phase synthesis of a dipeptide, which is the coupled to a second peptide in a solid phase reaction. The peptide is then cyclized following the coupling reaction. The methods and dipeptides are particularly useful for the synthesis of MC-4 receptor agonist peptides.

专利号:US-2024217995-A1
优先权日:2021-04-23
标 题 :Compositions for chemical synthesis of peptides
发明人：SEIFERT COLE
权利人:SEDERMA SA
摘要:The disclosure relates to compositions that can serve as anchors for the chemical synthesis of peptides. Anchor molecules can include GAP constituents, linker constituents, amino acid constituents, and/or stopper constituents. Anchor molecules can also include anchor peptides, wherein an anchor peptide can be removably coupled with an amino acid of a given sequence and act as a GAP anchor by achieving solubility control over the target peptide as it is synthesized via the addition of one or more other amino acids: the anchor peptide can then be removed from the target peptide. A novel method of peptide synthesis that utilizes novel anchor molecules and/or anchor peptides is also presented.

专利号:US-2025129495-A1
优先权日:2021-09-24
标 题:Method for the electrochemical synthesis of ammonia and apparatus for carrying out the method
发明人：FINKELSHTAIN GENNADI; BORCHTCHOUKOVA NINO; SHIROKOV ALEXANDER V; ENGLANDER JOSEPH ALEXANDER; SHARABI RONIT; ZABILSKIY MAXIM; TSAI TSEPIN
权利人:GENCELL LTD
摘要:A method for the electrochemical synthesis of ammonia (NH 3 ) comprises contacting a nitrogen-containing gas with the cathode of an electrochemical cell comprising a cathode, an anode, an alkaline aqueous electrolyte, and preferably an anion exchange membrane. The cathode is a porous gas diffusion electrode which comprises an active layer comprising a material which is capable of catalyzing the electrochemical reduction of nitrogen and is in contact with the electrolyte, a layer of electroconductive material supporting the active layer, and a porous polymer film on the side of the active layer which does not come into contact with the electrolyte and comes into direct contact with the nitrogen-containing gas. A potential over the electrochemical cell is applied to effect the electrochemical synthesis of ammonia from nitrogen and water. The method can be used to synthesize ammonia without using molecular hydrogen.

专利号:US-2018265547-A1
优先权日:2014-07-18
标 题 :Z-selective olefin metathesis of peptides
发明人：MANGOLD SHANE L; GRUBBS ROBERT H
权利人:CALIFORNIA INST OF TECHN
摘要:The invention relates generally to the synthesis of modified amino acids and modified peptides in the presence of cyclometalated catalysts. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry.