CAS: 132112-35-7; (S)-Ropivacaine Hydrochloride Hydrate

上下游产品

CAS号84057-95-4 罗哌卡因 | CAS号98717-15-8 盐酸罗哌卡因

盐酸罗哌卡因置于水体系中,化学反应 20.0H,反应生成盐酸柔匹华卡因一水合物
参考文献:Process Of Making Optically Pure L-Pipecolic Acid And Process Of Making Anesthetics And Intermediates Therefrom
标题:Process Of Making Optically Pure L-Pipecolic Acid And Process Of Making Anesthetics And Intermediates Therefrom
摘要:本发明描述了一种制备光学纯l-哌啶甲酸的新工艺,以及一种改进的工艺,用于将l-哌啶甲酸转化为l-N-(2,6-二甲基苯基)-1-丙基-2-哌啶甲酰胺,其盐酸酸盐和盐酸一水合物.

专利信息

专利号:US-2007166281-A1
优先权日:2004-08-21
标题 :Chloroquine coupled antibodies and other proteins with methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents such as therapeutic antibodies or insulin, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the drug is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to a drug directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing the drug for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and antibody or insulin to their site of action.