CAS: 70987-78-9; (S)-(+)-Oxirane-2-Methanol P-Toluenesulfonate

上下游产品

CAS号98-59-9 对甲苯磺酰氯(PTSC) | CAS号60456-23-7 (S)-缩水甘油 | CAS号107-18-6 烯丙醇 | CAS号46049-49-4 (S)-2,3-二氢-1,4-... | CAS号51594-55-9 左旋环氧氯丙烷 | CAS号23214-66-6 (R)-(-)-1-苄氧基-3... | CAS号16495-04-8 (S)-(+)-1-苄氧基-3... | CAS号98572-00-0 (S)-2-羟甲基-1,4-苯并二恶烷 | CAS号99291-25-5 左羟丙哌嗪 | CAS号71031-03-3 (S)-环氧丙基苯基醚 | CAS号161596-47-0 (S)-(+)-N-(2,3-... | CAS号56715-28-7 R-(-)-α-萘缩水甘油醚

烯丙醇 反应生成 (S)-(+)-对甲苯磺酸缩水甘油酯
参考文献:Byun,Hoe-Sup;Bittmann,Robert,Tetrahedron Lett.,30,(1989) N1,C. 2751-2754
标题:Byun,Hoe-Sup;Bittmann,Robert,Tetrahedron Lett.,30,(1989) N1,C. 2751-2754

专利信息

专利号:US-6087512-A
优先权日:1996-09-18
标题:Process for preparation of glycidyl ether
发明人：FURUKAWA YOSHIRO; KITAORI KAZUHIRO; YANAGIMOTO TETSUYA; MIKAMI MASAFUMI; YOSHIMOTO HIROSHI; OTERA JUNZO
权利人:DAISO CO LTD
摘要:A process for preparation of a glycidyl ether which is characrelized in reacting an epoxy compound of the formula ##STR1## wherein X is halogen or sulfonyloxy in the presence of a fluoride salt, with an alcohol. According to the above method, glycigyl ethers or their optically active compounds important as intermediates for synthesis of medicines are easily obtained in good yield and especially the optically active compounds are obtained with highly optical purity.

专利号:US-6057476-A
优先权日:1996-09-18
标题:Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers
发明人：FURUKAWA YOSHIRO; KITAORI KAZUHIRO; MIKAMI MASAFUMI; YOSHIMOTO HIROSHI; OTERA JUNZO
权利人:DAISO CO LTD
摘要:A process for preparation of 3-amino-2-hydroxy-1-propyl ether of the formula ##STR1## wherein R 1 is substituted or unsubstituted alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heterocyclic ring, R 2 and R 3 are the same or different hydrogen atom, a substituted or unsubstituted alkyl, or may form a ring together with an adjacent nitrogen atom, which ring may be interrupted with nitrogen atom, oxygen atom or sulfur atom, n which is characterized in reacting an epoxy compound of the formula ##STR2## wherein X is halogen, in the presence of a fluoride salt, with an alcohol and then reacting an amine. n According to the above method, an intermediates for synthesis of medicines is obtained in good yield and highly optical purity.

专利号:US-2009247618-A1
优先权日:2008-03-26
标题 :Process for preparation of benzo-fused heteroaryl derivatives
发明人：BALLENTINE SCOTT A; REANY LAURA
权利人:BALLENTINE SCOTT A; REANY LAURA
摘要:The present invention is directed to processes for the preparation of benzo-fused heteroaryl derivatives, useful for the treatment of epilepsy and related disorders. The present invention is further directed to processes for the preparation of intermediates in the synthesis of the benzo-fused heteroaryl derivatives.

专利号:US-2006111438-A1
优先权日:2004-10-21
标 题:Asymmetric synthesis of substituted dihydrobenzofurans
发明人：GONTCHAROV ALEXANDER V; KHAFIZOVA GULNAZ; POTOSKI JOHN R; YU QING; SHAW CHIA-CHENG; STACK GARY P; ZHOU DAHUI
权利人:WYETH CORP
摘要:The present invention concerns production of a compound of the formula n n nor a pharmaceutically acceptable salt thereof by a process which utilizes the cyclization of a compound of the formula: n n nwhere Ar, Y, R 1 , R y , R 2 , and m are as defined herein.

专利号:US-5612217-A
优先权日:1994-10-25
标 题 :Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthesis of HIV protease inhibitors
发明人：SHAFIEE ALI; CHEN SHIEH-SHUNG T; ARISON BYRON H; MILLER RANDALL R; GARRITY GEORGE M; HEIMBUCH BRIAN
权利人:MERCK & CO INC
摘要:Biotransformation products of a fermentation with culture MA7074 are potent HIV protease inhibitors. These products are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

专利号:US-6541647-B2
优先权日:1998-07-03
标 题:Methods of synthesis of substituted tetrahydrofuran compound
发明人：CHORGHADE MUKUND SHANKAR; GURJAR MUKUND KESHAO; KRISHNA PALAKODETY RADHA; LALITHA SISTA VENKATA SAI; SADALAPURE KASHINATH; ADHIKARI SUSANTA SEKHAR; MURUGAIAH ANDAPPAN MURUGAIAH S; MHASKAR SUNIL VYANKATESH; SHARMA GANGAVARAM VASANTHA MAD; PRASAD TANGALLAPALLY RAJENDRA; SREENIVAS PUNNA; REDDY VAVILALA GOVERDHAN; ISLAM AMINUL; PRASAD CHITTINENI HARI; RAO ALLA VENKATA RAMA
权利人:MILLENNIUM PHARM INC
摘要:The invention includes inter alia new methods for preparation of the pharmaceutically active compound 2-(4-fluorophenoxymethyl)-5-(4-N-hydroxyureidyl-1 -butynyl)-tetrahydrofuran and precursors thereof.