CAS: 73781-88-1; Ethyl 2-(Methylthio)Pyrimidine-5-Carboxylate

相似化合物

110099-94-0 90905-31-0 19858-50-5

上下游产品

CAS号5909-24-0 4-氯-2-甲硫基嘧啶-5-羧酸乙酯 | CAS号6191-97-5 3,3-二乙氧基丙酸 | CAS号867-44-7 |S|-甲基异硫脲硫酸盐 | CAS号10601-80-6 3,3-二乙氧基丙酸乙酯 | CAS号109-94-4 甲酸乙酯 | CAS号92385-43-8 3-二甲氨基-2-甲酰基丙烯酸乙酯 | CAS号14527-26-5 S-甲基异硫脲硫酸盐 | CAS号2986-19-8 2-甲基-2-疏基硫酸脲 | CAS号110099-98-4 1-(2-methylsulf... | CAS号110099-99-5 2-氯嘧啶-5-甲酰氯 | CAS号38324-83-3 2-羟基嘧啶-5-羧酸 | CAS号148550-51-0 2-甲砜基-5-嘧啶甲酸乙酯 | CAS号19858-50-5 2-甲硫基-5-嘧啶甲醇 | CAS号1108737-66-1 ethyl 1,6-dihyd... | CAS号57401-76-0 2-氨基嘧啶-5-甲酸乙酯 | CAS号110099-94-0 2-甲硫基嘧啶-5-甲酸

Ethyl 4-Chloro-2-Thiomethylpyrimidine-5-Carboxylate置于palladium 10% On Activated Carbon 氢气,Magnesium Oxide体系中,用 四氢呋喃,乙醇,水 作为反应溶剂,化学反应 3.0H,以83%的收率获得产物2-甲硫基-5-嘧啶羧酸乙酯
参考文献:Pyrimidinecarboxamide Derivatives And Their Use As Anti-Inflammatory Agents
标题:Pyrimidinecarboxamide Derivatives And Their Use As Anti-Inflammatory Agents
摘要:这项发明涉及以下式(i)的化合物:其中r1,R2,R3和r4如本文所述.这些化合物和含有这些化合物的药物组合物在治疗哺乳动物的炎症性疾病方面是有用的.

专利信息

专利号:US-RE47415-E
优先权日:2009-02-17
标题:Pyrimidinecarboxamides as CXCR2 modulators
发明人：MAEDA DEAN Y; ZEBALA JOHN A
权利人:SYNTRIX BIOSYSTEMS INC
摘要:There is disclosed pyridine- and pyrimidinecarboxamide compounds useful as pharmaceutical agents, synthesis processes, and pharmaceutical compositions which include pyridine- and pyrimidinecarboxamides compounds. More specifically, there is disclosed a genus of CXCR2 inhibitor compounds that are useful for treating a variety of inflammatory and neoplastic disorders.