919-30-2 = 919-30-2 + 2756137-96-7 反应条件:1.1 Solvents: Water; 4 H,90 °C 标题:Biocidal Properties Investigation Of The New Guanidine-Containing Alkoxysilanes And Siloxanes And Epoxy Materials Modified By Them 作者:Tarasenkov,A. N.; Drozdov,F. V.; Parshina,M. S.; Strukova,E. N.; Cherkaev,G. V.; Et Al 参考文献:Journal Of Organometallic Chemistry 日期:2022 卷标:959]
5089-70-3 = 919-30-2 反应条件:1.1 Reagents: Ammonia; 50 Min,30 - 200 Bar,180 °C 标题:Amination In Supercritical Ammonia - Continuous Production Of Aminoalkylsilanes 作者:Bauer,Andreas; Weis,Johann; Rauch,Jochen 参考文献:Organosilicon Chemistry Vi: Molecules To Materials 日期:2005 卷标:1 页码:167-169]
919-31-3 = 919-30-2 反应条件:1.1 Reagents: Hydrogen Catalysts: Thorium,Cobalt; 3 H,300 °C1.2 Reagents: Hydrogen Solvents: Ethanol; 1.4 - 1.8 Mpa,Rt; 1.8 Mpa -> 5 Mpa,Rt -> 150 °C; 3 H,5 Mpa,150 °C; 150 °C -> Rt 标题:Process For Preparation Of 3-Aminopropyltriethoxysilane By Hydrogenation Of 2-Cyanoethyltriethoxysilane In Presence Of Supported Cobalt-Thorium Catalyst 参考文献:Poland
专利号:US-7691316-B2 优先权日:2004-02-12 标 题:Devices and methods for the synthesis of nucleic acids 发明人:NGO NAM; JAQUINOD LAURENT; WANG HONG 权利人:CHEMISTRY & TECHNOLOGY FOR GEN 摘要:Cylindrical devices (frits) are prepared by embedding aminoalkyl- or mercaptoalkyl-modified Controlled Pore Glass (CPG) in high-density polyethylene. Methods and devices pertaining to their use in the synthesis of nucleic acids are described. A reusable synthesis column or a reusable 96-chamber synthesis plate have been designed to hold one to 96 of the said frits that are inserted reproducibly into the synthesis chambers with a frit insertor. A short gas surpressure is required to drive entry of chemical reagents into the said frit. Reagents are retained into the frit until a second, longer surpressure is applied to drain the said reagents.
专利号:US-7956011-B2 优先权日:2005-05-04 标题:Materials and methods for the photodirected synthesis of oligonucleotide arrays 发明人:SERAFINOWSKI PAWEL JERZY; GARLAND PETER BRYAN 权利人:CANCER RES INST ROYAL 摘要:Materials and methods for photodirected synthesis of oligonucleotide arrays on a solid substrate by photodirected synthesis are disclosed which employ a film formed from (i) a photoacid generator that on photolysis generates acid that is capable of directly removing the protecting group of the linker molecules or oligonucleotides and (ii) a polymer substantially lacking electronegative heteroatoms that are capable of hydrogen bonding with photogenerated acid. Methods of synthesizing an oligomer arrays are also described that use a film that restricts diffusion of reactants and products on the substrate during synthesis of the array and which includes a precursor of a deprotecting reagent. The method involves removing one or more of the non-required products of the deprotection reaction from the reactive array elements at which they are produced during the reaction, in order to displace the deprotection reaction towards completion.
专利号:US-2005101763-A1 优先权日:2003-09-30 标 题 :Synthesis of photolabile 2-(2-nitrophenyl)propyloxycarbonyl protected amino acids 发明人:DELISI CHARLES P; LAURSEN RICHARD A; BHUSHAN KUMAR R 权利人:UNIV BOSTON 摘要:The 2-(2-nitrophenyl)propyloxycarbonyl (NPPOC) group has been introduced as a photolabile amino protecting group for amino acids to be used as building blocks in photolithographic solid-phase peptide synthesis. NPPOC-protected amino acids were found to be cleaved in the presence of UV light about twice as fast as the corresponding o-nitroveratryloxycarbonyl (NVOC)-protected amino acids. The protected amino acids are of particular use in the synthesis of peptide arrays.
专利号:US-10768157-B2 优先权日:2015-10-20 标 题:Materials and methods for the detection of trace amounts of substances in biological and environmental samples 发明人:KABIR ABUZAR; FURTON KENNETH G 权利人:KABIR ABUZAR; FURTON KENNETH G; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES 摘要:The subject invention provides chemical compositions and synthesis strategies to create molecularly imprinted polymers (MIPs) via sol-gel processes. In a specific embodiment, the subject invention utilizes a(n) organic, inorganic, or metallic template analyte to create a hybrid organic-inorganic or inorganic three-dimensional network possessing cavities complementary to the shape, size, and functional orientation of the template molecule or ions. The subject invention further pertains to the use of the novel MIPs as selective solid phase extraction (SPE) sorbents for pre-concentration and clean-up of trace substances in biological and environmental samples. Synthesis of other molecularly imprinted polymers with environmental, pharmaceutical, chemical, clinical, toxicological, and national security implications can be conducted in accordance with the teachings of the subject invention.
专利号:US-2007122842-A1 优先权日:2005-11-30 标题 :Massively parallel synthesis of proteinaceous biomolecules 发明人:RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN 权利人:RAJASEKARAN JOHN J; TIWARI GUNJAN; CABEZAS EDELMIRA; FIDANZA JACQUELINE A; SUNDARARAJAN NARAYAN 摘要:Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner.
专利号:US-6040423-A 优先权日:1990-08-31 标题 :Process for synthesis of peptides 发明人:FRANK RONALD; GULER SINAN 权利人:BIOTECHNOLOG FORSCHUNG GMBH 摘要:The invention relates to a process for the rapid synthesis of support-bound or free peptides, a device for carrying out the process, a flat material with peptides bound to it which are prepared according to the process, and to a use for the flat material.
1: Amoli-Diva M, Pourghazi K. Gold nanoparticles grafted modified silica gel as a new stationary phase for separation and determination of steroid hormones by thin layer chromatography. J Food Drug Anal. 2015 Jun;23(2):279-286. doi: 10.1016/j.jfda.2014.11.005. Epub 2015 Feb 24. doi: 10.1039/c4an01596g. doi: 10.1016/j.talanta.2014.11.011. Epub 2014 Nov 14. doi: 10.1093/chromsci/bmu157. Epub 2014 Dec 4. doi: 10.3390/ijms15046412. 6: Bagheri H, Piri-Moghadam H, Ahdi T. Role of precursors and coating polymers in sol-gel chemistry toward enhanced selectivity and efficiency in solid phase microextraction. Anal Chim Acta. 2012 Sep 12;742:45-53. doi: 10.1016/j.aca.2012.02.021. Epub 2012 Feb 21. doi: 10.1016/j.jcis.2012.04.038. Epub 2012 May 23. doi: 10.3109/00016357.2011.630014. Epub 2012 Mar 9. doi: 10.1016/j.talanta.2011.06.021. Epub 2011 Jun 17. doi: 10.1016/j.colsurfb.2011.05.052. Epub 2011 Jun 6. doi: 10.1088/0957-4484/22/13/135605. Epub 2011 Feb 22. doi: 10.1016/j.chroma.2010.11.048. Epub 2010 Nov 27. doi: 10.3390/molecules15053618. doi: 10.1016/j.jconrel.2008.02.013. Epub 2008 Mar 6. 19: Kumar P, Agrawal SK, Misra A, Gupta KC. A new heterobifunctional reagent for immobilization of biomolecules on glass surface. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1097-9.
合成参考文献
参考文献:10.1007/s10529-010-0217-9 摘要:Huang J, Zhao R, Wang H, Zhao W, Ding L. Immobilization of glucose oxidase on Fe3O4/SiO2 magnetic nanoparticles. Biotechnol Lett. 2010 Jun;32(6):817–21. doi: 10.1007/s10529-010-0217-9. 参考文献:10.1007/s00216-010-3488-z 摘要:Hiep HM, Saito M, Nakamura Y, Tamiya E. RNA aptamer-based optical nanostructured sensor for highly sensitive and label-free detection of antigen–antibody reactions. Analytical and Bioanalytical Chemistry. 2010 Feb 16;396(7):2575–81. doi: 10.1007/s00216-010-3488-z. 参考文献:10.1007/s00216-011-5191-0 摘要:Yanagisawa N, Mecham JO, Corcoran RC, Dutta D. Multiplex ELISA in a single microfluidic channel. Analytical and Bioanalytical Chemistry. 2011 Jul 06;401(4):1173. doi: 10.1007/s00216-011-5191-0. 参考文献:10.1007/s11671-008-9174-9 摘要:Wu W, He Q, Jiang C. Magnetic Iron Oxide Nanoparticles: Synthesis and Surface Functionalization Strategies. Nanoscale Research Letters. 2008 Oct 02;3(11):397. doi: 10.1007/s11671-008-9174-9. 参考文献:10.1186/1556-276x-6-450 摘要:Zhang Y, Wu H, Huang X, Zhang J, Guo S. Effect of substrate (ZnO) morphology on enzyme immobilization and its catalytic activity. Nanoscale Research Letters. 2011 Jul 13;6(1):450. doi: 10.1186/1556-276x-6-450.