CAS: 95-54-5; 1,2-Phenylenediamine

上下游产品

o-benzoquinone-1,2-dioxime N-benzylidene-o-phenylenediamine 2-[(Ethoxycarbonyl)amino]aniline 1-(2-aminophenyl)-N2-phenylureaN1-(2-aminophenyl)-N2-phenylurea2-((2-hydroxyethyl)amino)aniline N-(2-mercapto-ethyl)-1,2-benzenediamine alloxazine acetoacetic acid-(2-amino-anilide)

邻二氯苯置于ammonium Hydroxide,Potassium Phosphate,Cu0.18Bi0.88O0.88I1.06体系中,用 乙醇,水 作为反应溶剂,化学反应 20.0H,以100%的收率获得产物邻苯二胺
参考文献:Cu I Bioi是适用于ullmann型cn偶联的高效新型催化剂,适用范围广-罕见的非光催化应用
标题:Cu I Bioi是适用于ullmann型cn偶联的高效新型催化剂,适用范围广-罕见的非光催化应用
摘要:制备了新的混合阳离子层状cu I Bioi,并探索了其非光催化催化性能.该固体物质由于在bi 2 O 2层中掺入cu I离子而具有bioi状,层状和挠曲结构.所制备的物质已通过xrd,拉曼,远红外,Uv Dr,Xp光谱,热(tg-Dtg)和分析(icp-Ms,Sem-Edx)方法,电子显微镜(sem,Tem)进行了全面表征作为bet表面积测量值.通过执行乌尔曼型cn测试了芳基卤化物与氨水之间的偶联反应,并对其催化能力进行了测试.考察了溶剂,添加碱和催化剂的量以及反应时间和反应温度的影响,并确定了绿色反应方式.还证明了催化剂的可回收性而不丧失活性,并且证明了其广泛适用于各种芳基卤化物.
DOI:10.1016/j.Mcat.2020.111072

专利信息

专利号:US-6531591-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:EP-1202998-B1
优先权日:1999-07-07
标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
发明人：FENSHOLDT JEF
权利人:EXIQON AS
摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

专利号:US-6251689-B1
优先权日:1998-05-14
标 题:Methods for the solid phase synthesis of combinatorial libraries of benzimidazoles benzoxazoles benzothiazoles and derivatives thereof
发明人：LABORDE EDGARDO; MATSUMOTO YUKIHARU
权利人:TELIK INC
摘要:The present invention provides an efficient and versatile method for the synthesis and screening of combinatorial libraries of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof. In order to expedite the synthesis of large arrays of compounds possessing these core structures, a general methodology for solid phase synthesis of these derivatives is provided. Arrays of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof useful as peptidomimetics and for the identification of agents having antifungal, antiviral, antimicrobial, anticoagulant, and antiulcer activity, or use in the treatment of inflammation, hypertension, cancer, and other conditions can be prepared by this method.

专利号:US-4347379-A
优先权日:1980-03-10
标 题:Synthesis of alpha-alkoxycarboxylic acids
发明人：LAI JOHN T
权利人:GOODRICH CO B F
摘要:Numerous alpha-carboxylic acids are prepared in a liquid medium by the reaction of an organic compound having at least one reactive hydroxyl or thiol group, with a monoketone, and a haloform, in the presence of a phase transfer catalyst and an alkali metal hydroxide. The term 'alpha-alkoxycarboxylic acids' includes alpha-phenoxycarboxylic acids, alpha-thioalkoxycarboxylic acids and alpha-thiophenoxycarboxylic acids. Specific substituents on the beta carbon atom of an alpha-alkoxycarboxylic (or '2-alkoxycarboxylic') acid reaction product formed in this novel synthesis, are introduced by appropriate choice of the ketone reactant; alkoxy and phenoxy substituents on the alpha carbon atom of a 2-alkoxycarboxylic acid are introduced by appropriate choice of the organic compound having a hydroxyl or thiol group. De-alkoxylation of the 2-alkoxycarboxylic acid yields alpha-beta monoolefinically unsaturated carboxylic acids which are necessarily alpha substituted, and may also be beta-substituted. It is now possible to produce, simply and conveniently, numerous substituted alpha-beta monolefinically unsaturated carboxylic acids with a variety of substituents on the alpha carbon atom, and, optionally on the beta carbon atom of these substituted carboxylic acids. Esters may also be conventionally derived from both the 2-alkoxycarboxylic acids, and the unsaturated carboxylic acids. During the phase transfer catalyzed synthesis of this invention, an intermediate acyl halide derivative is formed prior to the formation of the 2-alkoxycarboxylic acid reaction product. The formation of the acyl halide derivative allows the subsequent direct formation, in a modification of the same reaction, of 2-alkoxycarboxylic acid amides (or '2-alkoxycarbamides'), simply by adding a primary or secondary amine to the reaction mass. By dealkoxylation of the 2-alkoxycarbamides, specific, necessarily alpha-substituted and optionally beta-substituted acrylamides are synthesized which previously could be prepared, if at all, only with difficulty.

专利号:US-2004249114-A1
优先权日:2001-02-06
标题 :Methods of synthesis of polysuccinimide or polyaspartate by end capping polymerization
发明人：SWIFT GRAHAM; REDLICH GEORGE H; WEHBY JOHN NOLAN
摘要:Disclosed are methods of synthesis of homopolymers or copolymers containing succinimide or aspartate moieties formed in the presence of an end capping initiator. Also disclosed are methods of isolating, compounding, stabilizing and processing the homopolymers and copolymers.

专利号:US-4609707-A
优先权日:1983-11-10
标题 :Synthesis of polymers containing integral antibodies
发明人：NOWINSKI ROBERT C; HOFFMAN ALLAN S
权利人:GENETIC SYSTEMS CORP
摘要:A method is disclosed for the de novo synthesis of antibody-containing polymers and the preparation of a class of polymerizable compounds used in the synthesis of such antibody-containing polymers. Antibody-containing polymers formed from monomer/antibody conjugates and nonderivatized polymerizable compounds can be varied in formation of the polymer to provide control of (a) molecular spacing, steric accessibility and the number of antibody molecules that are integrally incorporated into the polymer backbone, and (b) the chemical and physical structure of the polymer itself, thus enabling specific tailoring of antibody-containing polymers for particular end-use application. Also disclosed is a method for the selective removal of a compound from a solution or suspension thereof using monomer/receptor conjugates where the compound has the capacity to bind to the receptor in the conjugate. The bound compound is removed by polymerization - induced separation of the monomer/receptor--compound complex from solution.