CAS: 4920-80-3; 3-Methoxy-2-Nitrobenzoic Acid

上下游产品

CAS号5345-42-6 3-甲基-2-硝基苯甲醚 | CAS号4920-77-8 2-硝基间甲酚 | CAS号108-39-4 间甲酚 | CAS号53055-05-3 3-甲氧基-2-硝基苯甲醛 | CAS号586-38-9 3-甲氧基苯甲酸 | CAS号591-31-1 3-甲氧基苯甲醛 | CAS号4900-66-7 2-甲氧基-1-硝基萘 | CAS号99-06-9 3-羟基苯甲酸 | CAS号108-24-7 乙酸酐 | CAS号7697-37-2 硝酸 | CAS号37466-89-0 1,2-二氨基-3-甲氧基苯 | CAS号3177-80-8 2-氨基-3-甲氧基苯甲酸 | CAS号42465-54-3 1-(2-氨基-3-甲氧基-苯基)-乙酮 | CAS号446-61-7 2-氟-6-甲氧基苯胺 | CAS号20876-31-7 3-甲氧基-2-硝基苯乙酸 | CAS号99595-85-4 3-甲氧基-2-硝基苯甲酰胺 | CAS号88377-31-5 5-甲氧基-9-氧代-9,10... | CAS号602-00-6 3-羟基-2-硝基苯甲酸 | CAS号1426317-26-1 3-hydroxy-6-iod... | CAS号5472-99-1 1-氯-3-甲氧基-2-硝基苯

3-甲氧基-2-硝基苯甲醛置于potassium Permanganate体系中,化学反应生成 3-甲氧基-2-硝基苯甲酸
参考文献:Rieche,Chemische Berichte,1889,Vol. 22,P. 2354
标题:Rieche,Chemische Berichte,1889,Vol. 22,P. 2354

专利信息

专利号:US-10889574-B2
优先权日:2016-06-17
标 题 :Method for producing diphenylmethane derivative
发明人：YOON HEE-KYOON; PARK SE-HWAN; YOON JI-SUNG; CHOI SOONGYU; SEO HEE JEONG; PARK EUN-JUNG; KONG YOUNGGYU; SONG KWANG-SEOP; KIM MIN JU; PARK SO OK
权利人:DAE WOONG PHARMA; GREEN CROSS CORP
摘要:The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.

专利号:CN-111138398-A
优先权日:2019-12-31
标题:Synthesis process of 2- (2-amino-3-methoxyphenyl) chromone