CAS: 42149-74-6; 2-Chloroethyln-Propylether

相似化合物

628-34-2 629-36-7 10503-96-5

上下游产品

CAS号71-23-8 正丙醇 | CAS号54509-73-8 ethene | CAS号473-29-0 二氯胺B | CAS号2807-30-9 乙二醇丙醚

乙丙醚置于吡啶,氯化亚砜,N,N-二甲基甲酰胺体系中,化学反应 3.0H,以98.9%的收率获得产物2-丙氧基氯乙烷
参考文献:2-丙氧基氯乙烷的合成工艺
标题:2-丙氧基氯乙烷的合成工艺
摘要:本发明属于有机合成技术领域,具体涉及2‑丙氧基氯乙烷的合成工艺.本发明在多种催化剂协同作用下,以乙二醇单正丙醚和氯化亚砜为主要原料,通过滴加氯化亚砜控制反应温度,后经升温,保温得到粗品,降温后直接加入固体碱分解过量氯化亚砜并中和,最后经过滤得到2‑丙氧基氯乙烷.与现有工艺相比,本发明所述催化剂廉价易得,催化效率更高,工艺过程简便,安全可靠,产品收率高,质量稳定,产品含量达99.2%以上,收率大于98.6%,生产成本更低,尤其适合工业化生产.

专利信息

专利号:WO-2019013789-A1
优先权日:2017-07-12
标 题 :ANTIMICROBIAL COMPOUNDS
发明人：REDDY HARIPRASADA R KANNA; SEBAHAR PAUL R; SERRANO CATHERINE M; LOOPER RYAN E
权利人:CURZA GLOBAL LLC; THE UNIV OF UTAH RESEARCH FOUNDATION
摘要:The invention relates to compounds of formula I or their pharmaceutically acceptable salts. The compounds of formula I are antimicrobial agents which inhibit, for example, Mycobacterium tuberculosis (Mtb) H37Ra. The compounds of formula I also have anti-tuberculous activity, exhibit limited cytotoxicity and inhibit protein synthesis. The invention also relates to methods of making compounds of formula I, as well as methods of using compounds of formula I for the treatment of bacterial infections, particularly tuberculosis.

专利号:WO-2019013790-A1
优先权日:2017-07-12
标题:ANTIMICROBIAL COMPOUNDS AND USES THEREOF
发明人：REDDY HARIPRASADA; SEBAHAR PAUL; LOOPER RYAN
权利人:CURZA GLOBAL LLC; THE UNIV OF UTAH RESEARCH FOUNDATION
摘要:The invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof. The compounds of formula I are antimicrobial agents which inhibit, for example, Mycobacterium tuberculosis (Mtb) H37Ra. The compounds of formula I also have anti-tuberculous activity, exhibiting limited cytotoxicity, and inhibiting protein synthesis. The invention also relates to methods of making compounds of Formula I, as well as methods of using the compounds of Formula I for the treatment of bacterial infections, particularly tuberculosis.

专利号:CN-102173998-A
优先权日:2011-03-21
标题 :Method for one-pot synthesis of herbicide pretilachlor

专利号:CN-108727211-A
优先权日:2017-04-19
标 题 :Method and device for continuous acylation synthesis of pretilachlor

专利号:CN-108727211-B
优先权日:2017-04-19
标 题:Method and device for continuous acylation synthesis of pretilachlor

专利号:CN-109232197-A
优先权日:2018-09-20
标 题:A kind of method of 2- positive propoxy ethyl alcohol chlorination synthesis chloromethyl positive propyl ether