专利号:US-9149659-B2 优先权日:2012-11-14 标题 :Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles 发明人:PUJOS MURIEL; BERNINI DOROTHEE; ROBERT CECILE; DOUCET OLIVIER 权利人:COTY GERMANY GMBH 摘要:The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.
专利号:CN-109053580-B 优先权日:2018-08-22 标 题 :Synthesis method of cosmetic dipeptide