CAS: 57773-63-4; Triptorelin

上下游产品

N-Alpha-芴甲氧羰基-N-In-叔丁氧羰基-D-色氨酸 1-Tert-Butoxycarbonyl-N-[(9-Fluorenyl)Methoxycarbonyl]-D-Tryptophan 163619-04-3
Fmoc-L-色氨酸(Boc)-Oh 3-[(S)-2-Carboxy-2-(9H-Fluoren-9-Ylmethoxycarbonylamino)Ethyl]Indole-1-Carboxylic Acid Tert-Butyl Ester 143824-78-6

在 三异丙基硅烷,1,2-乙二硫醇,三氟乙酸体系中,化学反应 2.0H,反应生成 曲普瑞林
参考文献:Methods For The Production Of Peptide Derivatives
标题:Methods For The Production Of Peptide Derivatives
摘要:这项发明涉及一种通过固相合成和后组装溶液相合成相结合的方法制备c-末端酰胺衍生物的肽.这些c-末端酰胺衍生物的肽进一步转化为肽醋酸酯.该发明还涉及纯肽醋酸酯和受保护的肽前体.

专利信息

专利号:US-12351573-B2
优先权日:2019-05-09
标 题:Compounds for use in synthesis of peptidomimetics
发明人：AL-ABED YOUSEF; CHENG KAI FAN
权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
摘要:Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.

专利号:US-2023159450-A1
优先权日:2020-05-08
标 题 :Dimers for use in synthesis of peptidomimetics
发明人：AL-ABED YOUSEF; ALTITI AHMAD
权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
摘要:Dimers for use in synthesis of peptidomimetics are described. Uses of dimers as synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the dimers and uses of azapeptides and other peptidomimetics are also described.

专利号:EP-0443532-B1
优先权日:1990-02-20
标题:Temporary minimal protection synthesis of LH-RH analogs
发明人：NESTOR JOHN J JR; MCCLURE NATALIE L
权利人:SYNTEX INC
摘要:A solid phase synthesis of LH-RH analogs in which the amino acids serine and histidine, if present, are side chain protected during the synthesis with groups labile to selected alpha -amino or deprotecting agents.

专利号:US-7122628-B2
优先权日:2000-12-22
标 题:Process for the synthesis of a peptide having a Trp residue
发明人：JACKSON STEVEN ALLEN
权利人:IPSEN MFG IRELAND LTD
摘要:A process for the solid phase synthesis of a peptide having at least one thyptophan residue, wherein said method comprises temporarily protecting the indole ring of said tryptophan residue with a side chain protecting group which is labile to a base wherein said protecting group is removed during cleavage of said peptide from the solid support.

专利号:US-2020354404-A1
优先权日:2019-05-09
标 题 :Peptidomimetic agents, synthesis and uses thereof
发明人：AL-ABED YOUSEF
权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
摘要:Compounds for use in synthesis of peptidomimetic agents; synthesis of peptidomimetic agents; peptidomimetic diagnostic and therapeutic agents; and uses of the compounds and peptidomimetic agents in drug discovery, diagnosis, prevention and treatment of diseases are described.

专利号:US-2005164912-A1
优先权日:2003-12-31
标 题:Methods for recovering cleaved peptide from a support after solid phase synthesis
发明人：BIGELOW ROGER D; CAIN ROBERT O
摘要:Methods for the solid phase synthesis of peptides and peptide intermediates, in particular methods involving recovering peptides from resin supports at excellent yield. In this invention, an alternating at least partially repeating cycle of shrinking and swelling treatments are used. Each shrinking or swelling part of a cycle may involve one or more washes. The process provides excellent recovery of peptide in a very efficient manner in terms of the number of individual washes and the total volume of wash reagents used.