CAS: 2386-56-3; Potassiummethanesulfonate

相似化合物

2550-61-0 2386-57-4 2386-52-9

上下游产品

n-°Ctyl methanesulfonate potassium thioacyanate potassium cyanide 2-°Ctyl mesylateDimethyldisulphide 18F]-potassium fluoride[18F]-potassium fluoride 1-n-butyl-3-methylimidazolium methanesulfonate

N-octyl Methanesulfonate 在 Cyclohexano-18-Crown-6 Potassium Cyanide体系中,用 水,氯苯作为反应溶剂,获得 壬基腈,Potassium Mesylate
参考文献:冠醚作为相转移催化剂.水-有机两相系统和低极性无水溶液中过氢二苯并-18-18-冠-6,亲脂性季盐和穴状配体的阴离子活化比较
标题:冠醚作为相转移催化剂.水-有机两相系统和低极性无水溶液中过氢二苯并-18-18-冠-6,亲脂性季盐和穴状配体的阴离子活化比较
摘要:在催化量的perhydrodibenzo-18-Crown-6存在下,在水-有机两相系统中进行的阴离子促进的亲核取代反应遵循相转移催化的经典机理.观察到的拟一阶速率常数与有机相中冠状冠醚的浓度线性相关.窄范围的反应性和序列中的反应中发现ñ辛基甲磺酸盐和均质系列在phcl-H阴离子的2 ö两相系统(N 3->我-〜溴-> Cn->氯-> Scn-)在无水phcl中基本保持不变.从这个角度来看,络合的冠醚与亲脂性季盐和隐窝化合物有很大的不同.确实,从两相状态变为无水状态时,阴离子水合层的去除受到较大的阳离子与阴离子相互作用的平衡,从而导致阴离子反应性的变化很小.这表明,与加密不同,络合冠醚几乎不能被视为"裸阴离子"的来源.还报道了作为相转移催化剂的亲脂冠醚,季盐和穴状配体之间的比较.
Doi:10.1039/P29800000046

专利信息

专利号:US-9023316-B2
优先权日:2010-04-08
标题:Synthesis of 18F-labeled tracers in hydrous organic solvents
发明人：GANGADHARMATH UMESH; WALSH JOSEPH; KOLB HARTMUTH
权利人:GANGADHARMATH UMESH; WALSH JOSEPH; KOLB HARTMUTH; SIEMENS MEDICAL SOLUTIONS
摘要:A method for synthesizing an 18 F-labeled probe. The method includes a step of eluting an amount of 18 F with a first solvent which includes a predetermined amount of water and at least one organic solvent. In this step, the 18 F elutes as an 18 F solution. The method also includes a step of using the 18 F solution to perform 18 F-labeling in the presence of at least one labeling reagent and at least one phase transfer catalyst so as to generate the 18 F-labeled probe. In the method, there is no step of drying the 18 F starting from a time when the eluting step is performed and ending at a time when the 18 F-labeling step is performed.

专利号:US-3900500-A
优先权日:1972-02-10
标题 :Esters of hydroxymethyl-dioxabicyclononene
发明人：WOODWARD ROBERT BURNS
权利人:CIBA GEIGY CORP
摘要:WHEREIN Z1 represents a free or an esterified hydroxy group, are produced by eliminating an ester group from a monoester or a diester of 2-hydroxymethyl-2,4-dioxabicyclo(3,3,1)nonane-7-ol; they are intermediates for the synthesis of prostaglandins. Compounds of formula

专利号:ES-2397104-T3
优先权日:2002-12-11
标 题 :Procedure and intermediate products for the synthesis of entecavir

专利号:US-3898248-A
优先权日:1972-02-10
标题 :Dioxatricyclodecenes
发明人：WOODWARD ROBERT BURNS
权利人:CIBA GEIGY CORP
摘要:A compound of the formula IS PREPARED BY ELIMINATING THE ESTER GROUP FROM ONE ESTER OF 9,10-DIOXATRICYCLO(4,3,1,03,8)DECAN-4 Beta -OL; IT IS AN INTERMEDIATE FOR THE SYNTHESIS OF PROSTAGLANDINS.

专利号:US-3950362-A
优先权日:1972-05-10
标 题 :Oxabicyclooctanes and process for their manufacture
发明人：WOODWARD ROBERT BURNS
权利人:CIBA GEIGY CORP
摘要:Compounds of the formula ##SPC1## n Wherein Z 4 and Z 5 each independently represent free, etherified or esterified hydroxy groups, are produced by diazotisation of 2-exo-amino-3,4-endo-dihydroxy-8-Z 4 -7-oxabicyclo [4,3,0]nonane followed by ring contraction, they are intermediates in the synthesis of prostaglandins.

专利号:JP-2013529186-A
优先权日:2010-04-08
标题 :Synthesis of 18F-labeled tracer in hydrous organic solvent