CAS: 18282-51-4; (4-Iodophenyl)Methanol

上下游产品

CAS号619-58-9 对碘苯甲酸 | CAS号51934-41-9 对碘苯甲酸乙酯 | CAS号15164-44-0 4-碘苯甲醛 | CAS号1711-02-0 4-碘苯甲酰氯 | CAS号619-44-3 4-碘苯甲酸甲酯 | CAS号302348-51-2 4-(羟甲基)苯硼酸频哪醇酯 | CAS号59016-93-2 4-(羟甲基)苯硼酸 | CAS号60-12-8 苯乙醇 | CAS号91-63-4 2-甲基喹啉 | CAS号100-51-6 苯甲醇 | CAS号3597-91-9 4-联苯甲醇 | CAS号349-95-1 4-(三氟甲基)苄醇 | CAS号39959-59-6 4-碘苄胺 | CAS号189132-01-2 1,1-二甲基乙基N-[(4-... | CAS号589-18-4 4-甲基苄醇 | CAS号623-05-2 对羟基苯甲醇 | CAS号538-39-6 1,2-二对甲苯基乙烷 | CAS号3058-39-7 4-碘苯甲腈 | CAS号86718-08-3 4-(1H-咪唑-1-基)苯甲醇 | CAS号87736-88-7 4-[3-(三氟甲基)-3H-...

4-溴苄醇置于碘,Sodium Iodide体系中,用 乙腈 用作溶剂,化学反应 36.0H,以78%的收率获得4-碘苄醇
参考文献:Photo-Induced Metal-Catalyst-Free Aromatic Finkelstein Reaction
标题:Photo-Induced Metal-Catalyst-Free Aromatic Finkelstein Reaction
摘要:The Facile Iodination Of Aromatic Compounds Under Mild Conditions Is A Great Challenge For Both Organic And Medicinal Chemistry. Particularly,The Synthesis Of Functionalized Aryl Iodides By Light Has Long Been Considered Impossible Due To Their Photo-Lability,Which Actually Makes Aryl Iodides Popular Starting Materials In Many Photo-Substitution Reactions. Herein,A Photoinduced Halogen Exchange In Aryl Or Vinyl Halides Has Been Discovered For The First Time. A Broad Scope Of Aryl Iodides Can Be Prepared In High Yields At Room Temperature Under Exceptionally Mild Conditions Without Any Metal Or Photo-Redox Catalysts. The Presence Of A Catalytic Amount Of Elemental Iodine Could Promote The Reaction Significantly.
Doi:10.1021/jacs.5B03220

专利信息

专利号:US-5512701-A
优先权日:1995-06-07
标题:Process for the synthesis of vinyl sulfenic acid derivatives
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.

专利号:US-6372945-B1
优先权日:1995-06-07
标 题 :Process for the synthesis of vinyl sulfoxides
发明人：AIKINS JAMES A; MILLER RANDAL SCOT; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfoxides, in particular diarylvinyl sulfoxides

专利号:US-5606076-A
优先权日:1995-06-07
标 题 :Process for the synthesis of benzo[b]thiophenes
发明人：AIKINS JAMES A; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a process for the synthesis of 2-arylbenzo[b]thiophenes.

专利号:US-5569772-A
优先权日:1995-06-07
标 题:Process for the synthesis of benzo[b]thiophenes
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of 2-aryl benzo[b]thiophenes, and to novel intermediates therefor.

专利号:US-5606075-A
优先权日:1995-06-07
标 题:Process for the synthesis of benzo[b]thiophenes
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to new processes for the synthesis of 2-aryl benzo[b]thiophenes.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.