CAS: 3342-78-7; 2-Aminophenylacetic Acid

上下游产品

CAS号3740-52-1 2-硝基苯乙酸 | CAS号59-48-3 2-吲哚酮 | CAS号551-93-9 邻氨基苯乙酮 | CAS号56-89-3 L-胱氨酸 | CAS号7732-18-5 水 | CAS号611-73-4 苯甲酰甲酸 | CAS号56-23-5 四氯化碳 | CAS号35613-44-6 (2-氨基-苯基)-乙酸甲酯 | CAS号59-48-3 2-吲哚酮 | CAS号21905-78-2 N-乙酰基吲哚酮 | CAS号614-75-5 邻羟基苯乙酸 | CAS号3359-49-7 3-亚苄基吲哚啉-2-酮 | CAS号18698-99-2 2-(2-氰基苯基)乙酸 | CAS号20921-96-4 (2-氰基苯基)乙酸甲酯 | CAS号74588-82-2 2-苄基-1H-吲哚-3-羧酸 | CAS号59050-38-3 2-phenyl-1H-ind... | CAS号39161-85-8 2-疏基苯乙酸

2-硝基苯乙酸置于palladium On Activated Charcoal 氢气体系中,用 甲醇 用作溶剂,化学反应生成2-氨基苯乙酸
参考文献:质子产生的偶极子.吲哚-3-羧酸的新合成
标题:质子产生的偶极子.吲哚-3-羧酸的新合成
摘要:(2-氨基苯基)乙酸的亚胺在温和的条件下得到2-取代的吲哚-3-羧酸.认为环化涉及1,5-偶极子,并最初产生相应的二氢吲哚.
Doi:10.1039/c39840000661

专利信息

专利号:WO-2022153263-A1
优先权日:2021-01-18
标 题 :Process for the synthesis of imepitoin
发明人：VERONESE MARTINO; BAROZZA ALESSANDRO; BETTONI PIERGIORGIO; ROLETTO JACOPO; PAISSONI PAOLO
权利人:PROCOS SPA
摘要:Disclosed is a process for the synthesis of imepitoin of formula (I) by reacting 4- chloroaniline, chloroacetic acid and urea in the presence of an apolar or weakly polar aprotic solvent such as xylene, and then reacting the resulting 1-(4- chlorophenyl)imidazolidine-2, 4-dione (II) with morpholine in the presence of morpholine hydrochloride. Crystallisation from dimethyl sulphoxide and methanol provides pure imepitoin (I). The process is cheaper and more easily industrially scalable than the known procedures, thus enabling imepitoin to be produced with high yields and limited costs.

专利号:US-2024209018-A1
优先权日:2021-03-22
标题:Universal linker reagents for dna synthesis
发明人：REED MICHAEL W; WU CHENG-HSIEN; COOPER JOHN; DEMPCY ROBERT O
权利人:GENSCRIPT USA INC; CUSTOMARRAY INC
摘要:Provided herein are methods and compositions for oligonucleotide synthesis utilizing universal linker phosphoramidites. Methods and reagents are described with DNA synthesis using controlled pore glass (CPG) solid supports, and on platinum coated electrodes for electrochemical DNA synthesis. The universal linkers can be used as spacers in single-column PCR primer synthesis to generate 2 strands with free 3′-hydroxy termini after cleavage. The methods and compositions utilize a solid support system for synthesis of oligonucleotides, wherein the support has platinum electrodes and a universal linker, optionally wherein the platinum electrode is coated with an amine. The methods and compositions further describe use of universal linker phosphoramidites and the platinum electrode is coated with a monosaccharide, or a disaccharide.

专利号:US-5527824-A
优先权日:1985-07-22
标题 :Substituted Di-T-Butlyphenols useful for inhibiting leukotriene synthesis
发明人：SCHERRER ROBERT A
权利人:RIKER LABORATORIES INC
摘要:Substituted Di-T-Butylphenols useful for inhibiting the synthesis of leukotrienes are disclosed.

专利号:WO-2025098683-A1
优先权日:2023-11-10
标 题:Improved process for the synthesis of imepitoin
发明人：ESTEVEZ LORA RAÚL; GARCÃ?A RAMOS Ã?LVARO; MARTINEZ GRAU MARÃ?A Ã?NGELES
权利人:JUSTESA IMAGEN S A U
摘要:The present invention describes an improved process for the preparation of imepitoin by means of an efficient preparation of its intermediate 1-(4- chlorophenyl)imidazolidine-2,4-dione followed by condensation with morpholine in the presence of ammonium chloride. Particularly, the invention relates to a process which provides imepitoin in high yield by removing the water generated in the reaction using a continuous process to distil, dry and recirculate the dried morpholine back to the reactor. More particularly, the invention relates to a process that provides imepitoin with very high purity by a simple washing with toluene and water. Still more particularly, the invention relates to a cost-effective process that is scalable for industrial application.

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:WO-9710221-A1
优先权日:1995-09-15
标 题:Synthesis of quinazolinone libraries
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TORREY PINES INST
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.