CAS: 22766-83-2; 2-Octyldodecyl Tetradecanoate

结构式图片

合成工艺路线路线简述

    2-辛基十二醇,肉豆蔻酸置于d(+)-10-樟脑磺酸体系中,化学反应 24.0H,以97%的收率获得2-辛基十二烷基十四酸酯
    参考文献:磺酸催化的露天无溶剂酯缩合反应
    标题:磺酸催化的露天无溶剂酯缩合反应
    摘要:酯缩合是最基本的有机转化之一,并且需要对当前酯化方法更环境友好的替代方法.在无溶剂和无干燥剂的条件下,催化量的磺酸促进羧酸和醇的等摩尔混合物之间的酯缩合.特别地,具有适当酸度的对甲苯磺酸(tsoh)和10-樟脑磺酸(csa)有效催化仲醇的酯缩合而不分解.由于本方案在简单的露天条件下不需要溶剂,因此可以在相当小的设备中合成大量的酯.
    Doi:10.1016/j.Tetlet.2008.06.058

    海关参考信息

    专利信息


    专利号:WO-2007094533-A1
    优先权日:2006-02-17
    标题:Composition for inhibiting collagen degradation and promoting collagen synthesis comprising emodin
    发明人:PARK DEOK HOON; LEE JONG SUNG; JUNG EUN SUN; HYUN CHANG GU; HONG SEONG TAEK
    权利人:BIOSPECTRUM INC; PARK DEOK HOON; LEE JONG SUNG; JUNG EUN SUN; HYUN CHANG GU; HONG SEONG TAEK
    摘要:Disclosed is a composition, comprising emodin, for inhibiting collagen degradation and promoting collagen synthesis. The composition stimulates cell regeneration by promoting the synthesis of collagen by normal fibroblasts, alleviates wrinkles, and imparts the skin with elasticity. Also, the composition can be used as a preparation for external use for skin, such as cosmetics.

    专利号:US-9339521-B2
    优先权日:2007-04-17
    标题:Use of vernonia extract
    发明人:SEGOND CAROLINE; LOISEAU ALAIN; PETIT VIRGINIE; THERON ERIC
    权利人:SEGOND CAROLINE; LOISEAU ALAIN; PETIT VIRGINIE; THERON ERIC; BAYER CONSUMER CARE AG
    摘要:The present invention relates to the use of an extract of a Vernonia plant from Madagascar in cosmetics, pharmaceuticals and food supplements for improving the skin status, more specifically by strengthening the dermal-epidermal junction and/or by activating fibroblasts synthesis of dermis and extracellular matrix compounds.

    专利号:WO-2024246279-A1
    优先权日:2023-05-31
    标 题 :Lightening compositions and use of compounds as depigmenting agents
    发明人:HUYSSEUNE SANDRA; VEITHEN ALEX
    权利人:CHEMCOM SA
    摘要:The present invention relates to a lightening composition comprising a lightening effective amount of a compound of formula (I), or a tautomer, a stereoisomer, a hydrate, a solvate, a salt, or a polymorph thereof, wherein R1, R2, R3, R4, R5, R6, R7, m and n are as defined in the description and claims. The present invention also relates to a compound of formula (I2) or a tautomer, a stereoisomer, a hydrate, a solvate, a salt, or a polymorph thereof, wherein R1, R2, R3, R4, R5, R6, and R7 are as defined in the description and claims. The present invention also relates to the use of at least one compound of formula (I) or any subgroup thereof, or mixtures thereof, as depigmenting agent. The present invention also relates to the use of at least one compound of formula (I) or any subgroup thereof, or the use of the lightening composition, for preventing and/or reducing pigmentation of normal skin. The present invention also relates to the use of at least one compound, or the use of the lightening composition according to the first aspect, for decreasing the amount of melanin in melanocytes, for decreasing melanin synthesis, for impairing melanin transport and/or for impairing the distribution of melanin in suprabasal layers.

    专利号:TW-I224010-B
    优先权日:1999-03-02
    标 题 :Promoter of proliferation of epidermal cells, promoter of collagen synthesis of fibroblasts and heightening agent of water-preservative function of epidermis

    专利号:EP-2153815-A1
    优先权日:2008-08-05
    标题 :Use of urea containing compositions
    发明人:TRULLAS CABANAS CARLOS RAMON; KRUTMANN JEAN PROF DR
    权利人:ISDIN SA
    摘要:The present invention relates to the use of a composition comprising urea for increasing the expression of at least one gene associated with the collagen synthesis within the dermis of the skin. nThe urea composition has been used for preventing/treating damages of the skin such as signs of aging, wrinkles, damages associated with UV-radiation, wounds, skin diseases.

    专利号:US-12226379-B2
    优先权日:2022-02-08
    标 题 :Highly sustainable compositions for modulation of gene expression in human skin, and methods of production thereof
    发明人:DUGAR DEEPAK
    权利人:VISOLIS TECH INC; VISOLIS INC
    摘要:Formulations containing biologically-produced, high-purity R-mevalonolactone are provided for modulating the expression of genes and metabolism related to epidermal turnover, hyaluronic acid synthesis, barrier function, anti-aging elasticity, extracellular matrix degradation, inflammation, stress, and pigmentation in human skin. The biologically-produced, high-purity R-mevalonolactone may be used as an ingredient in pharmaceutical, food, or cosmetic products and may be applied topically or ingested for modulation of gene expression and metabolism.
    武汉弘德悦欣医药科技有限公司
    小微企业
    信用代码: 91420102MA4K4WB79G法定代表人:袁洪杰
    注册资本:180万(元)企业类型:有限责任公司(自然人投资或控股)
    成立日期:2019-07-31登记机关:武汉市江岸区市场监督管理局
    注册地址: 武汉市江岸区车站路6号怡东大厦19层F室
    医药、生物工程、生物制品的技术开发、技术服务;医药中间体、化学助剂及化工产品(不含化学危险品)的销售。(依法须经审批的项目,经相关部门审批后方可开展经营活动)
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    地址: 武汉市江岸区车站路6号怡东大厦19层F室
    常规和库存产品*产品总量: 509

    平台资质认证✓营业执照✓
    辛基十二醇肉豆蔻酸酯
    2-OCTYLDODECYL MYRISTATE
    产品图片纯度:99
    250kg/drum
    第 1 / 1 页
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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 29(Suppl. 3):162-186,2010
    摘要:International Journal of Toxicology 34(Suppl.2):5-69, 2015
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