CAS: 380380-64-3; 5-Bromo-2-(2-Methyl-2H-Tetrazol-5-yl)Pyridine

上下游产品

CAS号380380-60-9 5-溴-2-(2H-四唑-5-基)吡啶 | CAS号74-88-4 碘甲烷 | CAS号1374651-37-2 5-溴-2-(2H-四氮唑-5... | CAS号97483-77-7 5-溴-2-氰基吡啶 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号624-28-2 2,5-二溴吡啶 | CAS号1220910-89-3 N-[3-氟-4-[6-(2-...

5-Bromopyridine-2-Methylimidate置于吡啶,盐酸,Sodium Nitrite体系中,用 水 用作溶剂,化学反应 8.5H,反应生成2-甲基-5-(5-溴吡啶-2-基)四氮唑
参考文献:特地唑胺中间体的合成方法
标题:特地唑胺中间体的合成方法
摘要:本发明提供了一种特地唑胺中间体的合成方法.特地唑胺中间体的合成方法包括下列步骤:步骤a:使化合物(I)中的氰基与醇发生加成反应,生成化合物(II)或化合物(II)的酸式盐;步骤b:用肼基或甲基肼基取代所述化合物(II)或化合物(II)的酸式盐上的烷氧基,生成化合物(III);步骤c:使化合物(III)与亚硝酸钠在酸性条件下反应,生成特地唑胺中间体(Iv).整体反应式为本发明解决了反应试剂易爆,剧毒,以及甲基异构副产物分离困难等问题.

专利信息

专利号:US-2010286211-A1
优先权日:2004-10-08
标题:Oxazolidinone derivatives as antimicrobials
发明人：DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
权利人:DAS BISWAJIT; AHMED SHAHADAL; YADAV AJAY SINGH; GHOSH SOMA; GUJRATI ARTI; SHARMA PANKAJ; RATTAN ASHOK
摘要:The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

专利号:EP-2757104-A1
优先权日:2008-10-10
标 题:Compounds used in the synthesis of oxazolidinones

专利号:EP-2757104-B1
优先权日:2008-10-10
标题 :Compounds used in the synthesis of oxazolidinones

专利号:CN-117567455-A
优先权日:2019-12-11
标 题 :A new type of oxazolidinone compound and its synthesis method and application