CAS: 4210-32-6; 4-(Tert-Butyl)Benzonitrile

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CAS号56108-12-4 4-(叔丁基)苯甲酰胺 | CAS号5406-57-5 4-叔丁基苯甲酸乙酯 | CAS号3972-65-4 对叔丁基溴苯 | CAS号140-29-4 苯乙腈 | CAS号123324-71-0 4-叔丁基苯硼酸 | CAS号180261-48-7 4-(TERT-BUTYL)B... | CAS号544-92-3 氰化亚铜 | CAS号939-97-9 对叔丁基苯甲醛 | CAS号89379-02-2 tert-butyl(iodo... | CAS号100-47-0 苯甲腈 | CAS号57774-77-3 4-叔丁基硫代苯甲酰胺 | CAS号175204-39-4 4-叔丁基苯苄胺肟 | CAS号126393-38-2 5-(4-叔丁基苯基)四唑 | CAS号68284-01-5 4-叔丁基苯甲脒盐酸盐 | CAS号84632-59-7 颜料橙73 | CAS号59528-30-2 4-叔丁基苄胺盐酸盐 | CAS号60028-84-4 4-tert-butyl-N-...

4-叔丁基甲苯置于ammonium Hydroxide,N-溴代丁二酰亚胺(Nbs),碘体系中,用 四氯化碳 作为反应溶剂,化学反应 6.0H,反应生成 4-叔丁基苄腈
参考文献:甲基芳烃直接氧化转化为芳族腈
标题:甲基芳烃直接氧化转化为芳族腈
摘要:各种methylarenes的通过在aibn或bpo催化量的存在下用nbs或dbdmh治疗成功转化成相应的芳族腈以非常好至适中的产率,然后用分子碘的反应是在水溶液nh 3在一-Pot过程.本反应是用于从甲基芳烃制备芳族腈的有用且实用的无过渡金属的方法.
DOI:10.1021/ol401906Q

专利信息

专利号:US-11247977-B2
优先权日:2018-06-22
标题 :Compound and use thereof in synthesis of brivaracetam intermediate and crude drug
发明人：FENG YAN; WANG RUYONG; YE YIZHANG; ZHANG FENGSEN; GONG XUAN; WANG ZHONGHONG; KANG XINSHAN
权利人:FUJIAN HAIXI PHARMACEUTICALS CO LTD
摘要:The present application provides a compound in formula III, and further provides a use of the compound in the synthesis of a Brivaracetam intermediate and a crude drug, and a synthesis method. A raw material involved in the method of the present application is low in costs and easily available; (R)-4-propyl-dihydrofuran-2-ketone having high optical purity can be prepared; complicated separation and purification steps are avoided; costs are reduced, and the method is more applicable to industrial production.

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.

专利号:US-2022411449-A1
优先权日:2019-11-13
标 题 :Method for Preparing Heteroleptic Triarylbismuthanes and Compounds Produced by the Same
发明人：HYVL JAKUB; LEHRER AXEL
权利人:UNIV HAWAII
摘要:A method for controlling dismutation in the synthesis of a heteroleptic triarylbismuthane is provided as are compounds produced by such a method and use of the same to inhibit the replication of microorganisms.

专利号:US-11767302-B2
优先权日:2020-10-01
标题 :Reagents and methods for tetrazine synthesis
发明人：FOX JOSEPH M; LAMBERT WILLIAM; FANG YINZHI; AM ENDE CHRISTOPHER WILLIAM; MAHAPATRA SUBHAM; XIE YIXIN; WANG CHUANQI
权利人:UNIV DELAWARE
摘要:Disclosed herein are mono- and di-substituted tetrazines and methods of their preparation and converting an oxetanyl ester to a thio-substituted tetrazine, which is then converted to a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine.

专利号:CN-107602415-A
优先权日:2017-09-25
标 题:A kind of Fe(â…¢) porphyrin-catalyzed method for the one-pot synthesis of aromatic nitriles by oxidizing aromatic olefins with nitrite

专利号:US-9149445-B2
优先权日:2009-07-27
标 题:Inhibition of glycerol-3-phosphate acyltransferase (GPAT) and associated enzymes for treatment of viral infections
发明人：LIU SEAN; RABINOWITZ JOSHUA D; SHENK THOMAS
权利人:LIU SEAN; RABINOWITZ JOSHUA D; SHENK THOMAS; UNIV PRINCETON
摘要:A method of treating or preventing a viral infection in a mammal by administering a compound or pharmaceutically acceptable derivative thereof that inhibits a phosphatidic acid synthesis enzyme.