CAS: 96-24-2; 3-Chloropropane-1,2-Diol

上下游产品

1,3-dibromo-2-chloro-propane silver(I) acetate oxiranyl-methanol allyl alcohol 3-piperidin-1-yl-propane-1,2-diol 4-chloromethyl-2-furan-2-yl-[1,3]dioxolane 1-(2,3-dihydroxy-propyl)-quinolinium; chloride H-pyridin-4-one1-(2,3-dihydroxy-propyl)-3,5-diiodo-1H-pyridin-4-one

3-氯丙烯置于methyltrioctylammonium Tetrakis(Diperoxotungsto)Phosphate 双氧水体系中,用 苯 作为反应溶剂,化学反应 4.0H,以74%的收率获得产物3-氯-1,2-丙二醇
参考文献:A Convenient Catalytic Method For The Dihydroxylation Of Alkenes By Hydrogen Peroxide
标题:A Convenient Catalytic Method For The Dihydroxylation Of Alkenes By Hydrogen Peroxide
摘要:报道了一种简便的方法,用于将相应的水不溶性烯烃转化为水溶性的邻二醇.该方法基于使用钨过氧配合物作为催化剂,在两相体系中以过氧化氢作为氧化剂.
DOI:10.1055/s-1989-27229

专利信息

专利号:US-5097089-A
优先权日:1987-08-29
标 题 :Synthesis of glycerol from formaldehyde
发明人：GRACEY BENJAMIN P; HUDSON BARRY; WILLIAMS PETER S
权利人:BP CHEM INT LTD
摘要:This invention relates to a process for synthesis of glycerol from formaldehyde, wherein formaldehyde under substantially anhydrous condition is self-condensed in a catalytic step is dihydroxyacetone which is separated from the self-condensation catalyst and hydrogenated catalytically to glycerol. n The feature of the invention is to have less than 0.4% w/w of water in the self-condensation reaction mixture thereby improving the process to produce glycerol in commercially viable rates and yields.

专利号:US-2017267706-A1
优先权日:2014-08-19
标 题:Method for the synthesis of heterocyclic hydrogen phosphine oxide
发明人：BRUYNEEL FREDERIC; NOTTE PATRICK PIERRE
权利人:STRAITMARK HOLDING AG
摘要:A method for the synthesis of a heterocyclic hydrogen phosphine oxide, having the general formula: n n n n n n n n n n wherein:n nR is a aliphatic or aromatic divalent group optionally including one or more heteroatoms and optionally having one or more substituents andn nX and Y are independently selected from —O—, —C(O)O— and —NR′—n nwherein R′ is a monovalent group optionally having one or more heteroatoms including the steps of:n na) forming a reaction mixture by mixing a compound having the general formula HX—R—YH and tetraphosphorus hexaoxide; andn nb) recovering the resulting compound comprising the heterocyclic hydrogen phosphine oxide.

专利号:US-6288244-B1
优先权日:1999-03-31
标 题 :Process for the preparation of 3, 4-dihydroxybutanoic acid and derivatives thereof from substituted pentose sugars
发明人：HOLLINGSWORTH RAWLE I
权利人:UNIV MICHIGAN STATE
摘要:A process for the preparation of 3,4-dihydroxybutanoic acid (I) and 3-hydroxy-γ-butyrolactone (V) thereof from a 3-leaving group substituted pentose source is described. In particular, the process relates to the synthesis of (R)-3,4-dihydroxybutanoic acid and (R)-3-hydroxy-γ-butyrolactone from a 3-leaving group substituted L-pentose sugars. The process uses a base and a peroxide to convert the pentose source to the chiral 3,4-dihydroxybutanoic acid compound. The chiral 3,4-dihydroxybutanoic acid can be further converted to 3-hydroxy-γ-butyrolactone by acidification. The chiral compound is useful as a chemical intermediate to the synthesis of various drugs and other products.

专利号:US-8772526-B2
优先权日:2009-12-21
标 题:Method for preparing dithiocarbamates in particular from polyols of the glycerol type
发明人：JEROME FRANCOIS; DE SOUSA RODOLPHE; BARRAULT JOEL; POUILLOUX YANNICK
权利人:JEROME FRANCOIS; DE SOUSA RODOLPHE; BARRAULT JOEL; POUILLOUX YANNICK; CENTRE NAT RECH SCIENT; UNIV POITIERS
摘要:The present invention concerns a method for the synthesis of glycerol dithiocarbamates or bis-dithiocarbamates (GDTCs) in which a reaction medium comprising (1) a carbonate selected from diethyl carbonate, dimethyl carbonate and ethylene or propylene carbonate associated with a glycerol type polyol in the presence of a basic catalyst or (2) a cyclic carbonate comprising five ring members, in a solvent medium, is supplemented with a primary or secondary amine in the presence of carbon disulphide, and the GDTC formed is recovered. In particular, a glycerol type polyol is brought into the presence of diethyl carbonate in the presence of a catalyst, then a primary or secondary amine is added to the reaction medium in the presence of carbon disulphide, and the GDTC formed is recovered. The invention can be used for one-step synthesis of glycerol dithiocarbamates directly from glycerol as the starting material and solvent. This method involves glycerol, diethyl carbonate, carbon disulphide (CS 2 ) and a primary or secondary amine to produce glycerol dithiocarbamates; the glycerol/NaOH phase can be recycled 6 times without a noticeable drop in yield; the ethyl acetate is also recycled after each extraction.

专利号:US-11753417-B2
优先权日:2019-01-17
标 题 :Synthesis of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene
发明人：GARA MOHAMAD; BECKER YIGAL
权利人:INT FLAVORS & FRAGRANCES INC
摘要:Disclosed is a scalable process for preparation of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene (BCE), a key intermediate for manufacture of fragrance ingredient 3-methylcyclopentadecenone (MUSCENONE®) and analogs through reaction of 3-Methyl-1,5-cyclopentadecanedione (MCPD) and analogs with a metal or metalloid alkoxide in high yield and purity.

专利号:US-9982072-B2
优先权日:2013-10-30
标 题 :Synthesis of acetal compounds
发明人：LOCCUFIER JOHAN
权利人:AGFA GRAPHICS NV; AGFA NV
摘要:A process for the preparation of optionally asymmetric acetal compounds includes reacting a compound containing a hydroxyl group with a vinylether compound in the presence of a zwitterionic catalyst including at least one basic nitrogen containing structural fragment and at least one sulfonic acid group in its structure, with the proviso that a molar ratio of the basic nitrogen to sulfonic acid is 1:1.