专利号:US-11760707-B2 优先权日:2019-11-13 标题 :Process for the synthesis of 2,3,3,3-tetrafluoropropene 发明人:ZHOU CHANGYUE; WANG YONG 权利人:FUJIAN YONGJING TECH CO LTD 摘要:The present invention pertains to a novel process of manufacturing the compound 2,3,3,3-tetrafluoropropene (1234yf). The compound 1234yf is the newest refrigerant with zero OPD (Ozone Depleting Potential) and zero GWP (Global Warming Potential). Thus, the invention relates to a process, involving a carbene generation route, for the manufacture of the compound 2,3,3,3-tetrafluoropropene (1234yf), of the compound 243db (2,3-dichloro-1,1,1-trifluoropropane), and optionally of the compound 2-chloro-1,1,1-trifluoropropene (1233xf) via carbene route and compound 243db (2,3-dichloro-1,1,1-trifluoropropane). The invention also relates to a process for the manufacture of the compound 2,3,3,3-tetrafluoropropene (1234yf), wherein the compound 243db (2,3-dichloro-1,1,1-trifluoropropane) serves as a starting material, for the manufacture of the compound 2,3,3,3-tetrafluoropropene (1234yf). Further, the invention relates to a process for the manufacture of the compound 2,3,3,3-tetrafluoropropene (1234yf), and of the compound 243db (2,3-dichloro-1,1,1-trifluoropropane), the initial starting materials are selected from the group consisting of com-pound 123 (2,2-dichloro-1,1,1-trifluoroethane), compound 124 (2-chloro-1,1,1,2-tetrafluoroethane), and compound 125 (pentafluoroethane).
专利号:US-12286399-B2 优先权日:2023-01-29 标 题:Synthesis of (R)(+)-2-(4-chloro-2-methyl phenoxy)propanoic acid in high enantiomeric excess 发明人:PATEL-FRAMROZE BOMI 权利人:PATEL FRAMROZE BOMI 摘要:Provided herein is a process to react optical active chloroalkyl acid alkyl ester and substituted phenols in an aromatic solvent in the presence of a catalytic quantity of a quaternary ammonium salt to yield an optically active substituted phenoxy alkyl acid.
专利号:US-2008214386-A1 优先权日:2004-03-01 标题:Catalyst for Cyclic Carbonate Synthesis 发明人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU 权利人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU 摘要:Provided are a solid catalyst which gives a cyclic carbonate at a high yield and a high selectivity, which is stable and which may be readily separated after reaction; and a method of industrially advantageous, inexpensive and safe production of a cyclic carbonate by the use of the catalyst. The catalyst contains an inorganic solid substance having a surface modified with an ionic substance containing a Group 15 element; or contains an ionic substance containing a Group 15 element, and an inorganic solid substance. The modifying group for surface modification of an inorganic solid substance is an ionic substance containing a Group 15 element. The ionic substance containing a Group 15 element is at least one substance selected from organic phosphonium salts, organic ammonium salts, organic arsonium salts and organic antimonium salts.
专利号:US-2024254069-A1 优先权日:2023-01-29 标题 :Synthesis of (r)(+)-2-(4-chloro-2-methyl phenoxy)propanoic acid in high enantiomeric excess
专利号:US-4684724-A 优先权日:1981-12-25 标题:4-Cyano-2-azetidinones and production thereof 发明人:OCHIAI MICHIHIKO; KISHIMOTO SHOJI; MATSUO TAISUKE 权利人:TAKEDA CHEMICAL INDUSTRIES LTD 摘要:4-Cyano-2-azetidinone derivatives represented by the formula ##STR1## wherein R 1 is an amino group which may be acylated or protected, X is a hydrogen atom or a methoxy group and W is a hydrogen atom or a sulfo group, and methods of producing the same, for example, as represented by ##STR2## wherein R 2 is an acylated or protected amino group, Y is a halogen atom or a group having the formula --OCOR 3 , --SCOR 3 or --S(O) n --R 3 (R 3 being a hydrocarbyl group and n an integer 1 or 2), R 4 is an amino group which may be acylated or protected and X is as defined above. Compounds [I] are useful as advantageous intermediates for the synthesis of optically active 4-substituted-2-azetidinone derivatives, and, when W=SO 3 H, [I] are also useful as antimicrobial agents and as beta-lactamase inhibitors.
专利号:US-2021139397-A1 优先权日:2019-11-13 标题:Process for the synthesis of 2,3,3,3-tetrafluoropropene
[参考文献]: A Kalkanci, Et Al. Assessment Of Susceptibility Of Mould Isolates Towards Biocides. J Mycol Med. 2015 Dec;25(4):280-6. [参考文献]: Dana Cervinkova, Et Al. The Role Of The Qaca Gene In Mediating Resistance To Quaternary Ammonium Compounds. Microb Drug Resist. 2013 Jun;19(3):160-7.
合成参考文献
摘要:Journal of the American Pharmaceutical Association, Scientific Edition., 38(428), 1949 参考文献:10.1007/s11356-020-10188-2 摘要:Mulder I, Schmittdiel M, Frei H, Hofmann L, Gerbig D, Siemens J. Soil water solutes reduce the critical micelle concentration of quaternary ammonium compounds. Environmental Science and Pollution Research. 2020 Aug 12;27(36):45311–23. doi: 10.1007/s11356-020-10188-2.