CAS: 2632-13-5; 2-Bromo-1-(4-Methoxyphenyl)Ethanone

相似化合物

5000-65-7 2491-38-5 41104-10-3

上下游产品

1-bromo-2-(4-methoxyphenyl)acetylene acetic acid methoxybenzene 2-Bromoacetyl bromide 1-(4-methoxy-phenyl)-2-piperidino-ethanone 1-ethyl-1-(4-methoxy-phenacyl)-piperidinium; bromide 2-(4-methoxyphenyl)-indolizine 2-(4-methoxyphenyl)imidazo[1,2-a]pyridine

对甲氧基苯乙酮置于pol(Vinylphenyltrimethylammoniumtribromide) Resin体系中,用 甲醇,水 用作溶剂,化学反应 1.0H,以93%的收率获得alpha-溴-4-甲氧基苯乙酮
参考文献:聚(乙烯基苯基三甲基三溴化铵)树脂作为高效聚合溴化剂在苯乙酮α-溴化和α-溴缩醛化中的应用
标题:聚(乙烯基苯基三甲基三溴化铵)树脂作为高效聚合溴化剂在苯乙酮α-溴化和α-溴缩醛化中的应用
摘要:摘要 报道了一种基于聚(乙烯基苄基三甲基氢氧化铵)树脂(amberlite 717)的新型负载型三溴化试剂的应用.这种负载的三溴化物树脂可在温和条件下直接用于苯乙酮的 α-溴化和 α-溴缩醛化,无需任何其他催化剂.研究了溶剂和负载的三溴化树脂的量对反应的影响.在最佳条件下,苯乙酮的大部分α-溴和α-溴缩醛以优异的收率被选择性地获得.图形概要
Doi:10.1080/00397911.2019.1631348

专利信息

专利号:WO-2021038581-A1
优先权日:2019-08-30
标题 :A one step synthesis of 2-substituted benzo[b]thiophenes
发明人：SEKAR GOVINDASAMY; POONGUZHALI ELAMVAZHUTHI
权利人:INDIAN INST TECH MADRAS
摘要:The invention pertains to a one step synthesis of 2-substituted benzo[ b ]thiophene of general formula wherein the synthesis of 2-substituted benzo[ b ]thiophenes is by reacting the starting materials substituted or unsubstituted 2-halogenobenzaldehyde and substituted or unsubstituted acetyl/phenacyl bromide with a catalyst, a sulphur source and phase transfer catalyst in an aqueous medium with atmospheric air and at temperature in the range of 25°C-30°C.

专利号:WO-0132645-A1
优先权日:1999-11-04
标题:The synthesis of extended bis(ethylenedithio)tetrathiafulvalene derivatives and their dihydroxyl analogues
发明人：OZTURK TURAN; TURKSOY FIGEN; WALLIS JOHN D; UMIT TUNCA
权利人:TUBITAK MARMARA RES CT; OZTURK TURAN; TURKSOY FIGEN; WALLIS JOHN D; UMIT TUNCA
摘要:The present invention describes the synthesis of six novel derivatives of bis(ethylenedithio)tetrathiafulvalene (BEDT-TTF), utilising the recently developed reaction of 1,8-diketones with Lawesson's reagent. These new BEDT-TTF derivatives (1)-(6) have potential to delocalise the positive charges formed during change-transfer salts to the peripheral. In addition to their positive charge delocalisation feature, the compounds (1)-(3) have the potential of being introduced hydrogen bonding groups and the compound (4)-(6) already have hydrogen bonding hydroxyl groups. All the new BEDT-TTF (7) derivatives described in this invention have shown comparative CV measurements with the BEDT-TTF. Each of these bis(ethylenedithio)tetrathiafulvalene derivatives of the present invention has a unique and novel structure which can not be found in the prior art and is useful for the development of new organic charge-transfer complexes.

专利号:US-2006287529-A1
优先权日:2003-02-20
标 题:Solid phase synthesis of antitumoral compounds
发明人：ALVAREZ MERCEDES; ALBERICIO FERNANDO; CIRONI PABLO; CUE VAS CARMEN; FRANCESCH ANDREAS; MARFIL MARTA
权利人:ALVAREZ MERCEDES; ALBERICIO FERNANDO; CIRONI PABLO; CUE VAS CARMEN; FRANCESCH ANDREAS; MARFIL MARTA
摘要:Lamellarins are prepared using a solid phase synthesis. In a first aspect, the process includes a step as follows: Formula (I) where R 1 to R 15 are as defined, and X is halogen, provided that one of R 2 , R 3 or R 4 is immobilised to a resin. In a second aspect, the process includes a step as follows: Formula (II) where R 1 ′ to R 5 ′, R 11 ′ and R 13 ′ are as defined, X 1 and X 2 are halogen, M is a metal function and PG is an amino protecting group, provided that one of that R 2 ′, R 3 ′ or R 4 ′ is immobilised to a resin.

专利号:US-2006199958-A1
优先权日:2003-04-14
标 题 :Process and intermediates for the preparation of pyrrolidine carboxylic acids
发明人：CVETOVICH RAYMOND; CHUNG JOHN Y; AMATO JOSEPH S; DIMICHELE LISA
权利人:CVETOVICH RAYMOND; CHUNG JOHN Y; AMATO JOSEPH S; DIMICHELE LISA
摘要:A novel process is provided for the preparation of pyrrolidine carboxylic acids, and the useful intermediates obtained therein. These compounds are intermediates for the synthesis of melanocortin-4 receptor (MC-4R), which are useful for the treatment of disorders such as obesity, diabetes, sexual dysfunction, male sexual dysfunction, and female sexual dysfunction.

专利号:US-6472531-B1
优先权日:1994-09-19
标题 :Synthesis of 3-[4-(2-aminoethoxy)-benzoyl]-2-aryl-6-hydroxybenzo[b]thiophenes
发明人：LABELL ELIZABETH SMITH; MCGILL JOHN MCNEILL; MILLER RANDAL SCOT
权利人:LILLY CO ELI
摘要:The present invention is directed to chemical processes for preparing 2-aryl-6-hydroxy-3-[4-(2-aminoethoxy)benzoyl]benzo[b]-thiophenes. The present invention is also directed to crystalline solvates and a non-solvated crystalline form of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]-benzo[b]thiophene hydrochloride, as well as processes for their preparation.

专利号:US-2004267028-A1
优先权日:2001-09-24
标题 :Preparation and use of pyrrole derivatives for treating obesity
发明人：SMITH ROGER A; KLUENDER HAROLD C; SU NING; LAVOIE RICO C; FAN JIANMEI
权利人:SMITH ROGER A; KLUENDER HAROLD C; SU NING; LAVOIE RICO C; FAN JIANMEI
摘要:This invention relates to pyrrole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.