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专利信息

专利号:US-7453011-B2
优先权日:2001-12-07
标题:Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
发明人：CLIFFORD LINDA; VALASINAS ALDONIA L; BLOKHIN ANDREI V; SARKAR APARAJITA; BASU HIRAK S; REDDY VENODHAR K; MARTON LAURENCE J; WANG YU
权利人:PROGEN PHARMACEUTICALS INC
摘要:Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.

专利号:US-2003195377-A1
优先权日:2001-12-07
标 题 :Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor

专利号:US-2006030735-A1
优先权日:2001-12-07
标题:Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor

专利号:US-2007287754-A1
优先权日:2001-12-07
标 题:Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor

专利号:US-7235695-B2
优先权日:2001-12-07
标题:Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor

专利号:EP-1453787-A1
优先权日:2001-12-07
标题:Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor