CAS: 887583-90-6; 4-Bromo-2-(Trifluoromethyl)Pyridine

相似化合物

1211580-54-9 1226800-12-9 436799-32-5

上下游产品

2-(trifluoromethyl)pyridin-4-amine N-(2-Methoxyethyl)-3-(2-[[2-(trifluoromethyl)pyridin-4-yl]methyl]-1-benzothiophen-7-yl)benzamide 1-(3-Bromo-4-methoxyphenyl)-4-fluoro-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine 6-chloro-4-fluoro-1-(3-methoxyphenyl)-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine 4-(2-Trifluoromethyl)pyridine-4-ylphenol

2-三氟甲基-4-氨基吡啶置于三氯溴甲烷,Sodium Nitrite,溶剂黄146体系中,用 二氯甲烷,水 作为反应溶剂,化学反应 1.08H,以38%的收率获得产物2-三氟甲基-4-溴吡啶
参考文献:一锅,无金属地将苯胺转化为芳基溴化物和碘化物
标题:一锅,无金属地将苯胺转化为芳基溴化物和碘化物
摘要:描述了通过从溴代三氯甲烷和二碘代甲烷中提取卤素从苯胺无金属合成芳基溴化物和碘化物.该一锅法反应以中等至优异的收率从相应的苯胺提供了卤代芳基卤化物,而没有分离出重氮盐.该转化反应时间短,后处理简单,对湿气和空气不敏感,并且避免了过多的卤化.dft计算支持s Rn 1机制.此方法代表了经典sandmeyer反应的一种方便替代方法.
DOI:10.1021/acs.Orglett.7B00771

专利信息

专利号:CN-117466745-A
优先权日:2023-11-02
标 题 :A method for photochemical manganese-catalyzed synthesis of aromatic amine compounds

专利号:CN-117466744-A
优先权日:2023-11-02
标 题:A method for photochemical iron-catalyzed synthesis of aromatic amine compounds

专利号:WO-2024022910-A1
优先权日:2022-07-26
标题 :1-[1-[2-(pyrimidin-4-yl)-1,2,4-triazol-3-yl]ethyl]-3-[2,4-dichloro-5-phenyl]urea derivatives and similar compounds as pesticides
发明人：WEISS MATTHIAS; JEANGUENAT ANDRE; KILARU JAGADEESH PRATHAP; MUEHLEBACH MICHEL; SCARBOROUGH CHRISTOPHER CHARLES; STOLLER ANDRé; SUESSE LARS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to compounds of formula (I) wherein: X is O or S; Q is Q a or Q b as pesticides and insecticides. Preferred compounds are e.g. 1-[1-[2-(pyrimidin-4-yl)-1,2,4-triazol-3-yl]ethyl]-3-[2,4-dichloro-5-phenyl]urea derivatives and similar compounds. An exemplary compound is e.g. 1-[(1S)-1-[2-(6-cyanopyrimidin-4-yl) -1,2,4-triazol-3-yllethyll-3-[2,4-dichloro-5-(trifluoromethyl)phenyllurea (example E1; compound P1). The present invention discloses the synthesis and characterisation of exemplary compounds as well as biological data thereof.

专利号:US-2025276972-A1
优先权日:2020-12-15
标 题:Compounds as casein kinase inhibitors
发明人：Zhou Enxing; LIU YUAN; WANG HANPING; WU GUANGLONG; SHAO NING
权利人:GRITSCIENCE BIOPHARMACEUTICALS CO LTD
摘要:Provided are casein kinase inhibitors, or pharmaceutically acceptable salts thereof. Corresponding pharmaceutical compositions, methods of synthesis, and intermediates are also provided.