CAS: 14486-52-3; 1-Methyl-2-(Methylthio)Imidazole

该化合物是一个环状异环结构,由两个氮原子和三个碳原子组成.该化合物具有一个甲基组和一个附属于伊迪达佐尔环的甲基组,具有独特的化学特性.它一般没有色素,可粉黄黄色液体或固体,取决于它在室温时的物理状态.该甲基基奥组的存在加强了其在各种有机溶剂中的再活动性和溶解性.1H-IMidazole衍生物因其生物活动而闻名,经常作为合成药物和农用化学物的中间体.该化合物可能具有抗微生物学或抗风化活动等特性,使其对医药化学具有兴趣.此外,其结构允许与生物系统的潜在互动,可以用于药物开发和材料科学的各种应用.安全数据应当用于处理和储存,如同所有化学物质一样,用于处理和储存.

英文名称1-Methyl-2-(Methylthio)Imidazole
中文名称1-甲基-2-(甲硫基)咪唑
IUPAC名称1-methyl-2-(methylthio)-1H-imidazole
其它别名1-Methyl-2-(Methylsulphanyl)-1H-Imidazole; 1-Methyl-2-(Methylthio)Imidazole(2Mmi); 2-Methylthio-3-Methylimidazole; 1H-Imidazole, 1-Methyl-2-(Methylthio)-; 1-Methyl-2-(Methylthio)Imidazole; Methimazole Impurity C; Methimazole Impurity 3; Thiamazole Impurity 3（thiamazole Impurity C)
CAS编号14486-52-3
MFCD编号:MFCD25959069
EINECS号:642-304-1
FDA UNII编号:VVW49QGF5P
分子式:C5H8N2S
分子量:128.2
产品CID: 683864
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: LKIVEIAXFZBGMO-UHFFFAOYSA-N
InChI=1S/C5H8N2S/c1-7-4-3-6-5(7)8-2/h3-4H,1-2H3…
计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数1.0

MSDS等安全信息

GHS象形图
GHS符号GHS08 & GHS07;
注释: Health hazard & Exclamation mark
危险类别生殖毒性类别2
皮肤致敏类别1
急性毒性类别4(经口)
严重眼刺激类别2
警示词Warning(警告)
危险描述H361fd |怀疑会影响生育能力. 怀疑对胎儿造成损害.
H317 |可能引起皮肤过敏反应.
H302 |吞咽有害.
H319 |造成严重眼刺激.
防范说明P261-P305+P351+P338-
安全声明H303+H313+H333
WGK Germany3

欧盟法规

C&L通报

上下游产品

1-methyl-1H-imidazole Dimethyldisulphide 1-methyl-1,3-dihydro-imidazole-2-thione dimethyl sulfate 1-methyl-2-(methylsulfonyl)-1H-imidazole 2-methanesulfinyl-1-methyl-imidazole 1-methyl-2-(methylsulfanyl)-5-nitro-1H-imidazole 1-methyl-2-methylsulphonyl-5-nitro-imidazole

合成工艺路线路线简述

2-[methyl-(1-Methyl-1H-Imidazol-2-yl)-λ4-Sulfanylidene]-Malonic Acid Dimethyl Ester 反应生成1-甲基-2-(甲硫基)咪唑
参考文献:Kametani,Tetsuji;Kawamura,Kuniaki;Akagi,Takeshi;Fujita,Chikako;Honda,+,Heterocycles,27,(1988) N1,C. 2531-2534
标题:Kametani,Tetsuji;Kawamura,Kuniaki;Akagi,Takeshi;Fujita,Chikako;Honda,+,Heterocycles,27,(1988) N1,C. 2531-2534

海关参考信息

2930909099-其他有机硫化合物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-6608196-B2
优先权日:2001-05-03
标题 :Process for solid supported synthesis of pyruvate-derived compounds
发明人：WANG BING; JANAGANI SATYANARAYANA; CALLAWAY WYETH B; SESSLER JONATHAN L
权利人:GALILEO PHARMACEUTICALS INC
摘要:Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.

专利号:US-3644392-A
优先权日:1969-05-12
标题:1-substituted-5-nitroimidazole-2-carboximidates
发明人：HENRY DAVID W
权利人:MERCK & CO INC
摘要:1-SUBSTITUTED - 5 - NITROIMIDAZOLE-2-CARBOXIMIDATES AND 1-SUBSTITUTED - 5 - NITROIMDAZOLE - 2 -CARBOXYLIC ACID ESTERS ARE PREPARED FROM 2-SUBSTITUTED - 5 - NITROMIDAZOLES BY TREATING A 1-SUBSTITUTED-2-CYANO - 5 -NITROIMIDAZOLE WITH BASE AND BY REACTING A 1-SUBSTITUTED-2-CYANO-5-NITROIMIDAZOLE WITH A LOWER ALKANOL IN THE PRESENCE OF BASE AND TREATING THE PRODUCT FORMED WITH A MINERAL ACID. THE 1SUBSTITUTED-5-NITROIMIDAZOLE-2-CARBOXYLIC ACID ESTERS AND THE 1-SUBSTITUTED - 5 - NITROIMIDAZOLE-2-CARBOXIMIDATES ARE USEFUL AS INTERMEDIATES IN THE SYNTHESIS OF BIOLOGICALLY ACTIVE 1-SUBSTITUTED-5-NITRIOMIDIDAZOLE-2-CARBOXAMIDES.

专利号:US-2003100750-A1
优先权日:2001-05-03
标题:Process for solid supported synthesis of pyruvate-derived compounds

专利号:BE-899094-A
优先权日:1983-03-08
标题 :PROCESS FOR THE PREPARATION OF CARBAPENEM DERIVATIVES, NOVEL SYNTHESIS INTERMEDIATES AND PROCESS FOR THE PREPARATION OF SUCH INTERMEDIATES.