CAS: 158923-11-6; [(R)-1-[(Sp)-2-(Dicyclohexylphosphino)Ferrocenyl]Ethyl]Di-Tert-Butylphosphine

专利信息

专利号:WO-2025078335-A1
优先权日:2023-10-09
标 题 :Processes for the preparation of deucravacitinib
发明人：ETAYO PÉREZ PABLO; PUJOL OLLÉ XAVIER; MOLINA NIETO JUAN
权利人:FARMHISPANIA GROUP S L
摘要:The invention relates to processes for the preparation of deucravacitinib of formula (XI), or a pharmaceutically acceptable salt thereof. It also relates to intermediates of formula (V') and (V'') as defined herein useful in the synthesis of this molecule.

专利号:JP-2009530403-A
优先权日:2006-03-21
标 题 :Synthesis of arylamines from reactions of aromatic compounds with ammonia or metal amides.

专利号:US-12202782-B2
优先权日:2020-11-19
标 题:Processes and intermediates for preparing MCL1 inhibitors
发明人：DIXON DARRYL D; ISCHAY MICHAEL A; JOHNSON TREVOR C; MERIT JEFFREY E; REGENS CHRISTOPHER S; STANDLEY ERIC A; STEINHUEBEL DIETRICH P
权利人:GILEAD SCIENCES INC
摘要:The present disclosure relates to methods and intermediates for the synthesis of certain compounds that inhibit MCL1, for use in the treatment of cancers.

专利号:WO-2025123046-A1
优先权日:2023-12-07
标 题:Synthesis of leucine-rich repeat kinase 2 modulators
发明人：STORZ THOMAS; DONG HANQING; CHEN CHUNGPIN HERMAN
权利人:ARVINAS OPERATIONS INC
摘要:Provided are methods for synthesizing compounds having activity against Leucine- rich repeat kinase 2 (LRRK2), as well as intermediates generated during said methods.

专利号:WO-2023178061-A1
优先权日:2022-03-15
标题 :Biocatalytic synthesis of (1s,3s)-3-hydroxycyclohexane-1-carboxylic acid compounds
发明人：MCKENNA SHANE; TAN YICHEN; SMITH MICHAEL J; FOX RICHARD J; GEORGE DAVID THOMAS; JOE CANDICE LEE
权利人:BRISTOL MYERS SQUIBB CO
摘要:Improved methods and intermediates thereof for preparing (1S,3S)-3-hydroxycyclohexane-1-carboxylic acid are described. These compounds are useful as intermediates for making carbamoyloxymethyl triazole cyclohexyl acid LPA antagonists.

专利号:EP-4493533-A1
优先权日:2022-03-15
标 题 :Biocatalytic synthesis of (1s,3s)-3-hydroxycyclohexane-1-carboxylic acid compounds