CAS: 169674-35-5; 5,6-Difluoro-1H-Indole-2-Carboxylic Acid

相似化合物

884494-61-5 3093-97-8 399-76-8

上下游产品

5,6-二氟吲哚-2-羧酸乙酯 Ethyl 5,6-Difluoro-1H-Indole-2-Carboxylate 169674-34-4

5,6-二氟吲哚-2-羧酸乙酯置于盐酸,Sodium Hydroxide体系中,用 乙醇 用作溶剂,化学反应生成5,6-二氟吲哚-2-羧酸
参考文献:Indole Derivatives
标题:Indole Derivatives
摘要:该发明涉及以下式的吲哚衍生物 ##str1## 其中r.Sup.1到r.Sup.4分别是氢,卤素,较低烷基,环烷基或三氟甲基,R.Sup.5和r.Sup.6分别是氢,卤素,较低烷基,环烷基,三氟甲基,羟基或较低烷氧基,R.Sup.7是氢或较低烷基,以及其在药学上可接受的酸盐.式i的化合物结合到5-羟色胺受体,因此在治疗和/或预防中枢神经系统疾病,如抑郁症方面具有用途.

专利信息

专利号:WO-2023002323-A1
优先权日:2021-07-19
标 题 :Synthesis of substituted tricyclic amides and analogues thereof

专利号:US-2024327419-A1
优先权日:2021-07-19
标 题 :Synthesis of substituted tricyclic amides and analogues thereof
发明人：MASON JEREMY; PALLERLA MAHESH; PAMULAPATI GANAPATI REDDY
权利人:ARBUTUS BIOPHARMA CORP
摘要:The present disclosure includes synthetic methods for preparing certain substituted tricyclic amides, which can be used to treat, ameliorate, and/or prevent hepatitis B virus (HBV) and/or hepatitis D virus (HDV) infections in a subject.

专利号:CN-117730082-A
优先权日:2021-07-19
标 题:Synthesis of substituted tricyclic amides and analogs thereof

专利号:KR-20240046184-A
优先权日:2021-07-19
标题 :Synthesis of substituted tricyclic amides and analogues thereof

专利号:EP-4373823-A1
优先权日:2021-07-19
标题:Synthesis of substituted tricyclic amides and analogues thereof

专利号:CA-3225801-A1
优先权日:2021-07-19
标 题:Synthesis of substituted tricyclic amides and analogues thereof