CAS: 23056-47-5; 2-Bromo-4-Methyl-5-Nitropyridine

相似化合物

156118-16-0 23056-45-3 1289213-78-0

上下游产品

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2-氨基-4-甲基-5-硝基吡啶置于亚硝酸特丁酯,Copper(I) Bromide体系中,用 乙腈 用作溶剂,化学反应 2.0H,以17%的收率获得2-溴-4-甲基-5-硝基吡啶
参考文献: Bicyclic Heteroaryl Compounds As Gpr119 Receptor Agonists[fr] Composés Hétéroaryles Bicycliques En Tant Qu'Agonistes Du Récepteur Gpr119
标题: Bicyclic Heteroaryl Compounds As Gpr119 Receptor Agonists[fr] Composés Hétéroaryles Bicycliques En Tant Qu'Agonistes Du Récepteur Gpr119
摘要:本发明提供了一类新的双环杂环芳基化合物,其化学式表示为(i),包含这些化合物的药物组合物,以及它们在调节gpr119活性以治疗代谢紊乱及其并发症方面的用途,以及治疗代谢紊乱及其并发症的方法.

专利信息

专利号:US-2025163076-A1
优先权日:2022-02-18
标 题 :Synthesis of bruton's tyrosine kinase inhibitors
发明人：TRAN NGOC DUC; XIOURAS CHRISTOS; CLEATOR EDWARD; MATON WILLIAM MARC; RAMMELOO THOMAS JOACHIM LANDEWALD; FERNANDES PHILIPPE; BONGARTZ JEAN-PIERRE A; CAO DUY CHI TRUNG; HORWITZ MATTHEW ALLAN; JUSSEAU XAVIER JEAN-MARIE; LEMAIRE SÉBASTIEN FRANCOIS-EMMANUEL; SCHWEITZER-CHAPUT BERTRAND
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present disclosure is directed to methods of synthesizing a compound of Formula (I), where the R groups are defined herein, and to methods of synthesizing a compound of Formula (II). Some aspects of the present disclosure is directed to converting the compound of Formula (II) into its P form.

专利号:US-7468375-B2
优先权日:2004-04-26
标题:Inhibitors of the HIV integrase enzyme
发明人：DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; WANG HAI; YANG ANLE; YIN CHUNFENG; ZHANG JUNHU
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.

专利号:WO-2023156599-A1
优先权日:2022-02-18
标 题 :Synthesis of bruton's tyrosine kinase inhibitors

专利号:EP-4479405-A1
优先权日:2022-02-18
标 题:Synthesis of bruton's tyrosine kinase inhibitors

专利号:CN-118715228-A
优先权日:2022-02-18
标题 :Synthesis of bruton's tyrosine kinase inhibitor