CAS: 2460-77-7; 2,5-Di-Tert-Butylcyclohexa-2,5-Diene-1,4-Dione

该化合物是一种代用苯甲quin衍生物,其结构由于在2和5个位置上存在三丁基乙基苯组而严重受阻,该化合物被广泛用作有机合成的中间体和聚合物化学的一种稳定剂或抑制剂,其树枝结构有助于抗氧化特性,其高热稳定性和对氧化的耐抗力使其适合于在恶劣条件下需要耐久性的应用.此外,该化合物在为催化系统准备功能性材料和离心剂方面起着先锋作用.该化合物定义明确的再活性和强性强调了其在工业和研究环境中的实用性.

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合成工艺路线路线简述

    1,4-Bis(Tert-Butyldimethylsiloxy)-2,5-Di-(Tert-Butyl)Benzene置于pyridinium Chlorochromate体系中,用 二氯甲烷 用作溶剂,化学反应 2.0H,以99%的收率获得2,5-二叔丁基-1,4-苯醌
    参考文献:Pyridinium Chlorochromate Releases Quinones From Hydroquinone Silyl Ethers
    标题:Pyridinium Chlorochromate Releases Quinones From Hydroquinone Silyl Ethers
    摘要:
    Doi:10.1021/jo00329A013

    海关参考信息

    专利信息


    专利号:US-9267213-B1
    优先权日:2005-03-25
    标题:Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array
    发明人:MAURER KARL; COOPER JOHN J
    权利人:CUSTOMARRAY INC
    摘要:There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.

    专利号:US-5414094-A
    优先权日:1990-01-26
    标 题 :High purity and high yield synthesis of dianhydrides
    发明人:CSAPILLA JOSEPH
    权利人:CYTEC TECH CORP
    摘要:A process for making a dianhydride product, said process comprising reacting two moles of maleic anhydride and one mole of a vinyl benzene compound in a reaction mixture comprising about 1.5 to 2.0 moles of the vinyl benzene compound per mole of maleic anhydride at reaction temperature in the range from 105° to 125° C. for time to complete the reaction, adding a polar organic liquid to the reaction product mixture and refluxing the mixture, cooling the mixture following reflux and adding a hydrocarbon liquid to precipitate the product, separating the solid dianhydride product by filtration, washing the solids on the filter and drying the solids to make the finished dianhydride product.

    专利号:US-2022323924-A1
    优先权日:2021-03-24
    标题:Electrochemical polynucleotide synthesis
    发明人:LACKEY JEREMY; HABIBIAN MARYAM; LIN YANYOU
    权利人:TWIST BIOSCIENCE CORP
    摘要:Provided herein are compositions, devices, systems and methods for generation and use of biomolecule-based information for storage. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.) Further provided are compositions for low voltage deprotection of polynucleotides.

    专利号:US-4609739-A
    优先权日:1984-11-06
    标 题:Synthetic routes to benzofurans and benzothiophenes and intermediates therefor
    发明人:GAMMILL RONALD B
    权利人:UPJOHN CO
    摘要:The present invention provides novel compositions of matter and processes for their preparation. More particularly, the present invention consists of novel chemical intermediates and associated processes for the preparation of khellin and other furochromone analogues, which have demonstrated antiatherosclerotic activity. These novel intermediates and processes can also be used for the preparation of benzofurans and benzothiophenes which inhibit the synthesis of leukotriene and/or lipoxygenase.

    专利号:MX-2007011815-A
    优先权日:2005-03-25
    标题 :ELECTROCHEMICAL UNLOCK SOLUTION FOR ELECTROCHEMICAL SYNTHESIS OF OLIGOMEROS IN AN ARRANGEMENT OF ELECTRODES.

    专利号:RU-2007139631-A
    优先权日:2005-03-25
    标题 :SOLUTION FOR ELECTROCHEMICAL DEPARTMENT IN ELECTROCHEMICAL SYNTHESIS OF OLIGOMERS ON THE ELECTRODE MATRIX
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    主要参考文献

    [参考文献]: H Westerblad, Et Al. The Role Of Sarcoplasmic Reticulum In Relaxation Of Mouse Muscle; Effects Of 2,5-Di(Tert-Butyl)-1,4-Benzohydroquinone. J Physiol. 1994 Jan 15;474(2):291-301.
    [参考文献]: J K Foskett, Et Al. Calcium Oscillations In Parotid Acinar Cells Induced By Microsomal Ca(2+)-Atpase Inhibition. Am J Physiol. 1992 Mar;262(3 Pt 1):C656-63.
    [参考文献]: L Missiaen, Et Al. 2,5-Di-(Tert-Butyl)-1,4-Benzohydroquinone And Cyclopiazonic Acid Decrease The Ca2+ Permeability Of Endoplasmic Reticulum. Eur J Pharmacol. 1992 Dec 1;227(4):391-4.
    [参考文献]: M T Clunes, Et Al. P2U Purinoceptor Modulation Of Intracellular Ca2+ In A Human Lung Adenocarcinoma Cell Line: Down-Regulation Of Ca2+ Influx By Protein Kinase C. Cell Calcium. 1996 Oct;20(4):339-46.
    [参考文献]: M Wictome, Et Al. The Importance Of The Hydroxyl Moieties For Inhibition Of The Ca(2+)-Atpase By Trilobolide And 2,5-Di(Tert-Butyl)-1,4-Benzohydroquinone. Biochem Biophys Res Commun. 1994 Mar 15;199(2):916-21.

    合成参考文献


    摘要:Jie, X.; Su, W., Science of Synthesis, (2022) , 32.
    摘要:Weast, R.C. and M.J. Astle. CRC Handbook of Data on Organic Compounds. Volumes I and II. Boca Raton, FL: CRC Press Inc. 1985., p. V1 255
    摘要:Dean, J.H., M.I. Luster, A.E. Munson, I. Kimber. Immunotoxicology and Immunopharmacology. 2nd ed. New York, NY: Raven Press, Ltd., 1994., p. 577
    摘要:Wang, P.-S.; Sayed, M.; Gong, L.-Z., Science of Synthesis: Knowledge Updates, (2023) 1, 215.
    摘要:Wang, P.-S.; Sayed, M.; Gong, L.-Z., Science of Synthesis: Knowledge Updates, (2023) 1, 189.
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