CAS: 287-92-3; Cyclopentane

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CAS号120-92-3 环戊酮 | CAS号542-92-7 环戊二烯 | CAS号201230-82-2 carbon monoxide | CAS号33240-34-5 环戊基溴化镁 | CAS号142-29-0 环戊烯 | CAS号96-41-3 环戊醇 | CAS号185-94-4 housane | CAS号111-24-0 1,5-二溴戊烷 | CAS号71-43-2 苯 | CAS号1120-70-3 1,1-二氟环戊烷 | CAS号3400-45-1 环戊甲酸 | CAS号120-92-3 环戊酮 | CAS号703-13-9 CYCLOPENTYL TRI... | CAS号123-56-8 丁二酰亚胺 | CAS号137-43-9 溴代环戊烷 | CAS号3234-49-9 1,2-二溴戊烷 | CAS号18926-24-4 3-Bromopropanoy... | CAS号4524-93-0 环戊基甲酰氯 | CAS号628-17-1 1-碘戊烷 | CAS号109-67-1 1-戊烯

环戊酮置于氢氧化钾,二乙二醇乙醚,一水合肼体系中,化学反应生成环戊烷
参考文献:小环化合物.三,环丁酮,环丁醇,环丁烯和环丁烷的合成
标题:小环化合物.三,环丁酮,环丁醇,环丁烯和环丁烷的合成
摘要:在目前的工作中,研究了从亚甲基环丁烷制备环丁酮的方法.由于将该程序应用于大规模实验室操作相对困难,因此没有尝试臭氧化.通过将亚甲基环丁烷氧化为 1-(羟基甲基1)-1-环丁醇并用四乙酸铅裂解二醇,可得到令人满意的环丁酮收率.Gustavson 之前通过用稀高锰酸钾水溶液氧化亚甲基环丁烷,以 40% 的收率获得了 1-(羟基甲基)-1-环丁醇.在本研究中,使用 Roebuck 和 Adkins 制备反式环己二醇-1,2 所用程序的改进,通过过甲酸氧化实现了 80-83% 的收率.在使用叔丁醇中的过氧化氢的单个实验中获得了 39% 的收率.在二氯甲烷溶液中用四乙酸铅氧化二醇得到高达90%的环丁酮收率.乙二醇的高碘酸盐氧化不成功.来自季戊四醇的环丁酮的总产率为40%.
Doi:10.1021/ja01180A013

专利信息

专利号:EP-4092127-A1
优先权日:2021-05-18
标题:Enzyme-catalytic method for the direct stereoselective synthesis of gamma-(acyloxy) carboxylic acids
发明人：PARVE JAAN; KUDRJASHOVA MARINA; GATHERGOOD NICHOLAS; PARVE OMAR
权利人:TALLINN UNIV OF TECHNOLOGY
摘要:The present invention is a method for the stereoselective straightforward synthesis of gamma-acyloxy carboxylic acids of novel structure starting from racemic gamma-hydroxy carboxylic acid salts that are obtained by alkaline hydrolysis of the racemic gamma-lactones. The salt is acylated by enzyme catalysis in an organic solvent containing an acyl donor and an immobilised lipase, on stirring at room temperature (ca 20 °C) until reaching the conversion rate required. After that, the reaction mixture is acidified and extracted and the product treated with catalytic amount of para-toluenesulfonic acid in toluene during the time required for the relactonisation of the unreacted salt enantiomer. Thereafter, the target gamma-acyloxy carboxylic acid formed from one enantiomer of the starting compound and relactonised gamma-lactone formed from the other, unreacted enantiomer of the starting compound are isolated using a routine separation method, such as distillation, extraction with NaHCO3 water solution followed by acidification or column chromatography.

专利号:US-2016031800-A1
优先权日:2013-03-14
标 题:Synthesis of chiral kynurenine compounds and intermediates
发明人：TRETYAKOV ALEXANDER; DROUET KEITH E; SANDERS WILLIAM
权利人:VISTAGEN THERAPEUTICS INC
摘要:Provided are methods for the synthesis of compounds including chiral kynurenine compounds, intermediates useful for the synthesis thereof, and related compounds. For example, methods are provided for the synthesis of L-4-chlorokynurenine.

专利号:US-6184168-B1
优先权日:1997-09-22
标题:Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst
发明人：LYNCH THOMAS J
权利人:BRIDGESTONE CORP
摘要:The invention provides a catalyst composition, comprising: (a) an organolithium compound; and, (b) an organic acid salt of lanthanide series element; wherein: (1) only components (a) and (b) are required to promote the synthesis of 1,4-trans-polybutadiene; (2) the ratio of component (a) to component (b) is selected to maximize formation of the trans structure of said 1,4-trans-polybutadiene; and, (3) components (a) and (b) are selected for enabling further diblock synthesis. The invention further contemplates a process for using the catalyst to synthesize 1,4-trans-polybutadiene and other polymers and copolymers having trans configuration in the conjugated diene monomer contributed units.

专利号:US-2008086013-A1
优先权日:2006-06-15
标 题:Carbometallation of alkynes and improved synthesis of uniquinones
发明人：LIPSHUTZ BRUCE H
权利人:UNIV CALIFORNIA
摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

专利号:US-6872840-B1
优先权日:2003-09-17
标 题 :Synthesis of 8-membered carbocyclic compound having diexomethylene groups
发明人：CHO YONG SEO; CHANG MOON HO; KOH HUN YEONG; PAE AE NIM; KANG HYUN JUNG
权利人:KOREA INST SCI & TECH
摘要:The present invention relates to a synthesis of an 8-membered carbocyclic compound having diexomethylene groups, more particularly to a synthesis of an 8-membered carbocyclic compound having diexomethylene groups, a novel compound having the structure represented by the following Chemical Formula 1, from trimethylsilanylmethyl-allenol derivative by the intramolecular Prins cyclization using Lewis acid. The 8-membered carbocyclic compound is a useful intermediate for synthesis of other multicarbocyclic compounds. n n n In Chemical Formula 1, R 1 is a phenyl group, and R 2 and R 3 is a hydrogen atom, or R 1 , R 2 and R 3 may be connected with neighboring substituents to form a 5 to 10-membered aliphatic or aromatic ring.

专利号:US-2012302756-A1
优先权日:2010-02-19
标 题 :Process for synthesis of 2-substituted pyrrolidines and piperadines
发明人：LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
权利人:LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
摘要:The present invention provides a highly efficient, versatile one-step process for asymmetric synthesis of either diastereomer of 2-substituted pyrrolidines from a single starting material with excellent yields and high diastereoselectivety. Also provided is a method for the asymmetric synthesis of both diastereomers of 2-substituted piperidines with good yields and excellent diastereoselectivety. Diasteroselectivity is controlled effectively by choice of reducing agent.