CAS: 5431-44-7; 2,6-Pyridinedicarboxaldehyde

相似化合物

1195-59-1 15658-60-3 2893-33-6

上下游产品

6-methyl-2-pyridinecarboxaldehyde 2,6-Dibromopyridine isopropylmagnesium chloride N,N-dimethyl-formamide H-pyrazol-4-yl)-methyl]-pyridine2,6-bis-[bis-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-methyl]-pyridine pyridine-2,6-dicarbaldehyde-bis thiosemicarbazone (1E,1'E)-1,1'-(pyridine-2,6-diyl)bis(N-phenylmethanimine) 2,6-bis-(1,3-diphenyl-imidazolidin-2-yl)-pyridine

2,6-二甲基吡啶置于selenium(Iv) Oxide体系中,用 邻二氯苯 作为反应溶剂,化学反应 4.0H,以50%的收率获得产物吡啶-2,6-二甲醛
参考文献:强烈区分不同g-四链体拓扑的无环寡杂芳基
标题:强烈区分不同g-四链体拓扑的无环寡杂芳基
摘要:感觉:制备了具有交替的恶唑和吡啶基序的非大环g-四链体粘合剂家族.所示的七环衍生物对某些四链体拓扑表现出前所未有的结合偏好:它仅在na +缓冲液中识别人端粒四链体,但在k +缓冲液中不识别.这种独特的四链结合谱在很大程度上取决于配体的大小,并且可能是由凹槽相互作用引起的.
DOI:10.1002/anie.201103422

专利信息

专利号:US-2014275582-A1
优先权日:2013-03-14
标 题 :Chiral 2-arylpropyl-2-sulfinamide and chiral n-2-arylpropyl-2-sulfinylimines and synthesis thereof
发明人：LI GUIGEN
权利人:LI GUIGEN; UNIV TEXAS TECH; NANJING UNIVERSITY INST OF CHEMISTRY AND BIOMEDICAL SCIENCES
摘要:Provided herein are novel chiral sulfinamide and imine compounds. Also provided herein are methods of synthesizing novel chiral sulfinamide and imine compounds comprising simplified purification methods when compared to prior methods. The novel chiral sulfinamide and imine compounds are useful, for example, in the synthesis of complex natural products and pharmaceutical important compounds.

专利号:US-6861531-B2
优先权日:2002-03-27
标 题:Synthesis of 2,6-dicarbonylpyridines
发明人：GATELY DANIEL A
权利人:BOULDER SCIENT CO
摘要:Synthesis of 2,6-dicarbonylpyridines in solution in a hydrocarbon medium is described. The solutions of 2,6-dicarbonylpyridines may be used directly in further syntheses.

专利号:US-9216953-B2
优先权日:2012-11-02
标题 :Chiral 2-arylpropyl-2-sulfinamide and chiral N-2-arylpropyl-2-sulfinylimines and synthesis thereof
发明人：LI GUIGEN; PINDI SURESH
权利人:LI GUIGEN; PINDI SURESH
摘要:Provided herein are novel chiral sulfinamide and imine compounds. Also provided herein are methods of synthesizing novel chiral sulfinamide and imine compounds comprising simplified purification methods when compared to prior methods. The novel chiral sulfinamide and imine compounds are useful, for example, in the synthesis of complex natural products and pharmaceutical important compounds.

专利号:US-9051302-B2
优先权日:2008-01-15
标 题 :Synthesis of resorcylic acid lactones useful as therapeutic agents
发明人：WINSSINGER NICOLAS; BARLUENGA SOFIA; KARPLUS MARTIN
权利人:WINSSINGER NICOLAS; BARLUENGA SOFIA; KARPLUS MARTIN; UNIV STRASBOURG
摘要:Disclosed are macrocyclic compounds of formulae I, I′, II, II′, III, III′, IV, and V, which are analogs of the pochonin resorcylic acid lactones, pharmaceutical compositions comprising the compounds, and methods and uses comprising the compounds for the treatment of diseases mediated by kinases and Heat Shock Protein 90 HSP90.

专利号:WO-2014093723-A2
优先权日:2012-12-12
标 题 :Group-assistant-purification (gap) synthesis of velcade, dimeric analogs, and amino compounds
发明人：LI GUIGEN
权利人:NANJING UNIVERSITY OF TECHNOLOGY

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.