三聚乙醛置于盐酸,Potassium Permanganate体系中,化学反应生成 氯乙醛缩二乙醇 参考文献:Freundler,Bulletin De La Societe Chimique De France,1907,Vol. <4>1,P. 67 标题:Freundler,Bulletin De La Societe Chimique De France,1907,Vol. <4>1,P. 67
专利号:US-7122693-B2 优先权日:1988-04-11 标题 :Acetaldehyde acetal compounds, their synthesis, and uses thereof 发明人:BELLEAU EXECUTRIX OF ESTATE PI; DIXIT DILIP M; NGUYEN-BA NGHE 权利人:SHIRE BIOCHEM INC 摘要:The acetaldehyde compounds, 2-thiobenzoylacetaldehyde diethylacetal, 2-benzoyloxyacetaldehyde bis(2-methoxyethyl)acetal, 2-hydroxyacetaldehyde bis( 2-methoxyethyl)acetal, 2-thiobenzoylacetaldehyde bis(2-methoxy-ethyl)acetal, and 2-thioacetaldehyde bis(2-methoxyethyl)acetal, are useful as intermediates in the synthesis of substituted 1,3-oxathiolanes and substituted 1,3-dioxolanes.
专利号:US-4216159-A 优先权日:1978-05-25 标题 :Synthesis of 16-unsaturated pregnanes from 17-keto steroids 发明人:HESSLER EDWARD J; VANRHEENEN VERLAN H 权利人:UPJOHN CO 摘要:17-Keto steroids (I) in their protected form (IIa or IIb) are reacted with a metalated olefin (VI) to give a 21-aldehyde (IV) which is readily transformed to a 16-unsaturated pregnane (V) which is useful in the production of commercially important substituted corticoids.
专利号:US-5449836-A 优先权日:1992-12-07 标 题:Process for the preparation of vitamin A and intermediate compounds which are useful for this process 发明人:CHABARDES PIERRE 权利人:RHONE POULENC NUTRITION ANIMAL 摘要:A process for the preparation of vitamin A which preferably comprises bringing cyclogeranyl sulphone into contact with a C10 aldehyde acetal, halogenating the derivative obtained and then removing the halogen group and the sulphone, removing the acetal group and isomerizing the retinal obtained to the desired configuration. Also disclosed are compounds useful as intermediates in the synthesis of vitamin A and processes for preparation of these intermediate compounds.
专利号:US-2003087918-A1 优先权日:1988-04-11 标题 :Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties
专利号:US-4207088-A 优先权日:1977-06-30 标题:Herbicidal 1,3-dioxanes 发明人:KONZ MARVIN J 权利人:FMC CORP 摘要:A new class of herbicidal compounds consisting of 1,3-dioxanes carrying substituents other than hydrogen in the 2-, 4-, 5-, and 6-positions of the dioxane ring exhibits preemergence and postemergence herbicidal activity, controlling effectively the growth of selected grassy species. The synthesis of members of this class is described in detail, and the utility of representative compounds in exemplified.
专利号:US-3624143-A 优先权日:1968-05-10 标题 :Compounds of the class {62 -aralkylthio-substituted-{60 -amino acids 发明人:SHEN TSUNG-YING; WALFORD GORDON L; DORN CONRAD P JR 权利人:MERCK & CO INC 摘要:Beta -Aralkylthio-substituted- Alpha -amino acids and derivatives thereof useful as antiinflammatory agents are described. A process for preparing some of these amino acids by reaction of the corresponding aldehydes or ketones in the Strecker or hydantoin synthesis is shown.
[参考文献]: J C Kandala, Et Al. 2-Chloroacetaldehyde And 2-Chloroacetal Are Potent Inhibitors Of Dna Synthesis In Animal Cells. Biochem Biophys Res Commun. 1990 Mar 16;167(2):457-63.
合成参考文献
摘要:Tang, R.-Y., Science of Synthesis: Knowledge Updates, (2024) 1, 437. 参考文献:10.1515/znc-2003-11-1205 摘要:Ivanova A, Khozin-Goldberg I, Kamenarska Z, Nechev J, Cohen Z, Popov S, Stefanov K. Lipophylic compounds from Euphorbia peplis L.--a halophytic plant from the Bulgarian Black Sea coast. Z Naturforsch C J Biosci. 2003 Nov;58(11-12):783–8. doi: 10.1515/znc-2003-11-1205.