CAS: 6311-35-9; 6-Bromonicotinic Acid

上下游产品

CAS号3510-66-5 2-溴-5-甲基吡啶 | CAS号5006-66-6 6-羟基烟酸 | CAS号1603-41-4 2-氨基-5-甲基吡啶 | CAS号5006-66-6 6-羟基烟酸 | CAS号149806-05-3 6-BROMO-N-METHO... | CAS号941294-58-2 6-溴烟酸叔丁酯 | CAS号246034-30-0 3-Pyridinecarbo... | CAS号82846-28-4 6-二甲胺基烟酸 | CAS号889676-37-3 6-溴烟酰胺 | CAS号58757-38-3 6-氯吡啶-3-羰酰氯 | CAS号6271-78-9 6-氯烟酰胺 | CAS号122306-01-8 6-溴吡啶-3-甲醇 | CAS号168173-56-6 2-溴-5-(氯甲基)吡啶

2-溴-5-醛基吡啶置于1,4-Dithio-D,L-Threitol,Recombinant Aldehyde Dehydrogenase From Escherichia Coli,Water‐forming Nadh Oxidase From Streptococcus Mutans,β-烟酰胺腺嘌呤二核苷酸体系中,用 Aq. Phosphate Buffer 作为反应溶剂,化学反应 4.0H,反应生成 6-溴烟酸
参考文献:醛化学选择性有氧氧化成羧酸的生物催化方法
标题:醛化学选择性有氧氧化成羧酸的生物催化方法
摘要:在此,我们提出了一项使用三种重组醛脱氢酶(aldh)将醛氧化为羧酸的研究.aldh 以纯化形式与烟酰胺氧化酶 (Nox) 一起使用,该酶以双氧(大气压下的空气)为代价回收催化 Nad + .为了更方便的实际应用,还使用冻干全细胞和静息细胞生物催化剂研究了该反应.优化的生物催化氧化在 Ph 8.5 和 40 oc 的磷酸盐缓冲液中运行.从一组 61 种脂肪族,芳基脂肪族,苄基,杂芳族和双环醛中,其中 50 种以较高的产率转化(高达 >99%).少数邻位取代的苯甲醛,双环杂芳醛和2-苯基丙醛除外.在所有情况下,预期的羧酸都是唯一的产物(>99% 化学选择性).同一分子内的其他可氧化官能团(例如羟基,烯烃和杂芳族氮或硫原子)保持不变.该反应规模用于氧化 5-(羟甲基)糠醛 (2 G)(一种生物基原料),得到 5-(羟甲基)糠酸,分离收率为 61%.新的生物催化方法避免使用有毒或不安全的氧化剂,强
DOI:10.1039/c8Gc01381K

专利信息

专利号:US-7151112-B1
优先权日:2001-09-04
标题:Pharmaceutical uses and synthesis of nicotinamides
发明人：CUTSHALL NEIL S; JEFFREY SCOTT C
权利人:UCB SA
摘要:This invention is directed to methods of using a compound of the formula n nand pharmaceutically acceptable salts thereof, wherein n, X, R 1 and R 2 are disclosed herein, for treating inflammatory events in an animal subject.

专利号:US-6777432-B1
优先权日:2001-09-04
标 题 :Pharmaceutical uses and synthesis of nicotinamides

专利号:CN-113322490-A
优先权日:2020-02-28
标题:In situ synthesis of copper nanowire array material, preparation method and application thereof

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.

专利号:US-RE48547-E
优先权日:2010-08-23
标 题:Aminopyrimidinecarboxamides as CXCR2 modulators
发明人：MAEDA DEAN Y; ZEBALA JOHN A; SCHULER AARON D
权利人:SYNTRIX BIOSYSTEMS INC
摘要:There are disclosed aminopyrimidinecarboxamide compounds useful as pharmaceutical agents, synthesis processes, and pharmaceutical compositions which include aminopyrimidinecarboxamides compounds. More specifically, there is disclosed a genus of CXCR2 inhibitor compounds that are useful for treating a variety of inflammatory and neoplastic disorders.

专利号:US-2011250135-A1
优先权日:2008-09-12
标 题 :Piperazine Derivatives for Binding and Imaging Amyloid Plaques and Their Use
发明人：SCHMITT-WILLICH HERIBERT; ROEHN ULRIKE; FRIEBE MATTHIAS; LEHMANN LUTZ; FITZNER ANSGAR; KRAUSE SABINE; BROCKSCHNIEDER DAMIAN; DYRKS THOMAS; THIELE ANDREA; BOEMER ULF; MOENNING URSULA; HEINRICH TOBIAS
权利人:BAYER SCHERING PHARMA AG
摘要:The invention relates to compounds of formula I, their synthesis and their use, in particular for detecting amyloid deposits in a patient.