CAS: 72-40-2; 5-Amino-1H-Imidazole-4-Carboxamide Hydrochloride

相似化合物

64236-33-5 360-97-4 2167393-33-9

上下游产品

CAS号360-97-4 5-氨基-4-甲酰胺咪唑 | CAS号111105-67-0 5-氨基-4-(氨基羰基)-1... | CAS号85622-93-1 替莫唑胺 | CAS号5098-11-3 5-氨基-1H-咪唑-4-甲腈 | CAS号21190-16-9 4-氨基-1H-咪唑-5-羧酸乙酯 | CAS号118966-30-6 ACETIC ACID 2-(... | CAS号21343-04-4 5-氨基-1-甲基-1H-咪唑... | CAS号91026-74-3 5-acetamido-3H-... | CAS号59695-49-7 methyl N-(5-car... | CAS号59727-29-6 Carbamic acid,[... | CAS号3815-69-8 5-amino-1-benzy...

4-氨基-5-咪唑甲酰胺置于盐酸体系中,用 甲醇,水 作为反应溶剂,化学反应 0.5H,以84%的收率获得产物4-氨基-5-咪唑甲酰胺盐酸盐
参考文献:一步合成5-氨基-1 H-咪唑-4-羧酰胺的进展
标题:一步合成5-氨基-1 H-咪唑-4-羧酰胺的进展
摘要:描述了一种从市售的次黄嘌呤(约30美元/千克)合成5-氨基-1 H-咪唑-4-羧酰胺(aic)的有效方法.关键水解步骤的开发和实际隔离使aic的高效一步制造过程成为可能,对环境的影响最小,并且生产成本显着降低.
DOI:10.1021/acs.Oprd.1C00013

专利信息

专利号:US-7737284-B2
优先权日:2001-01-18
标题 :Synthesis of temozolomide and analogs
发明人：KUO SHEN-CHUN; MAS JANET L; HOU DONALD CHEN-TUNG
权利人:SCHERING PLOUGH CORP
摘要:This invention relates to a novel process for the synthesis of Temozolomide, an antitumor compound, and analogs, and to intermediates useful in this novel process.

专利号:US-6844434-B2
优先权日:2001-01-18
标题 :Synthesis of temozolomide and analogs
发明人：KUO SHEN-CHUN
权利人:SCHERING CORP
摘要:This invention relates to a novel process for the synthesis of temozolomide, an antitumor compound, and to intermediates useful in this novel process.

专利号:US-3857842-A
优先权日:1970-05-06
标题:Process for preparing purine compounds by reaction of a carbonitrile with formic acid
发明人：ASAI N
权利人:SAGAMI CHEM RES
摘要:An improved process for preparing purine compounds of the formula WHEREIN X is selected from the group consisting of an amino and a hydroxy group, and Y is selected from the group consisting of an amino and a hydroxy group and hydrogen, which are useful as precursors for the synthesis of organic compounds, as well as a process for preparing a carboxyamide of the formula USEFUL AS AN INTERMEDIATE FOR THE SYNTHESIS OF THE ABOVE PURINE COMPOUNDS ARE

专利号:US-3884827-A
优先权日:1970-12-09
标 题 :Process for preparing quanine
发明人：ASAI NORIO
权利人:SAGAMI CHEM RES
摘要:An improved process for preparing purine compounds of the formula WHEREIN X is selected from the group consisting of an amino and a hydroxy group, and Y is selected from the group consistng of an amino and a hydroxy group and hydrogen, which are useful as precursors for the synthesis of organic compounds, as well as a process for preparing a carboxyamide of the formula USEFUL AS AN INTERMEDIATE FOR THE SYNTHESIS OF THE ABOVE PURINE COMPOUNDS ARE

专利号:US-2005131227-A1
优先权日:2001-01-18
标 题:Synthesis of temozolomide and analogs

专利号:US-2006229456-A1
优先权日:2001-01-18
标 题:Synthesis of Temozolomide and analogs