CAS: 98437-24-2; Benzofuran-2-Boronic Acid

相似化合物

402503-13-3 929626-27-7 143381-72-0

上下游产品

CAS号1104637-65-1 2-苯并呋喃基硼酸甲基亚氨基二乙酸酯 | CAS号7732-18-5 水 | CAS号33094-66-5 2-硝基苯并呋喃 | CAS号41717-32-2 苯并呋喃-2-甲腈 | CAS号248-66-8 10h-苯并呋喃并[3,2-b]吲哚 | CAS号553-86-6 苯并呋喃酮 | CAS号118959-02-7 2-(cyclopenten-... | CAS号1104637-65-1 2-苯并呋喃基硼酸甲基亚氨基二乙酸酯 | CAS号1839-72-1 2-苯基-1-苯并呋喃 | CAS号782-18-3 4-(1-苯并呋喃)苯胺 | CAS号65246-50-6 2-thiophen-2-yl... | CAS号65715-20-0 2-(三氟甲基)苯并呋喃

2-Benzofuranylboronic Acid Mida Ester置于sodium Hydroxide体系中,用 四氢呋喃,水 作为反应溶剂,化学反应 0.33H,以89%的收率获得产物苯并呋喃-2-硼酸
参考文献:Knapp,David M.; Gillis,Eric P.; Burke,Martin D.,Journal Of The American Chemical Society,2009,Vol. 131,P. 6961-6963
标题:Knapp,David M.; Gillis,Eric P.; Burke,Martin D.,Journal Of The American Chemical Society,2009,Vol. 131,P. 6961-6963

专利信息

专利号:US-2022356182-A1
优先权日:2009-03-27
标题 :Inhibitors of hepatitis c virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOLL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-11053243-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOIL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9090661-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; MCCAULEY JOHN A; LUDMERER STEVEN W; LIU KUN; VACCA JOSEPH P; WU HAO; HU BIN; SOLL RICHARD; SUN FEI; WANG XINGHAI; YAN MAN; ZHANG CHENGREN; ZHENG MINGWEI; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-12150934-B2
优先权日:2016-11-30
标 题 :Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases
发明人：SIDDIQUI ARSHAD M; CIBLAT STEPHANE; CONSTANTINEAU-FORGET LEA; GRAND-MAITRE CHANTAL; GUO XIANGYU; SRIVASTAVA SANJAY; SHIPPS GERALD W; COOPER ALAN B; OZA VIBHA; KOSTURA MATTHEW W; LUTHER MICHAEL; LEVINE JEDD
权利人:BANTAM PHARMACEUTICAL LLC
摘要:Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by “aâ€?, R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

专利号:US-2011098483-A1
优先权日:2008-03-27
标题 :Substituted Nitrogen Heterocycles and Synthesis and Uses Thereof
发明人：PETASIS NICOS A; MYSLINSKA MALGORZATA
权利人:UNIV SOUTHERN CALIFORNIA
摘要:The invention relates to a nitrogen heterocycle compound of formula 1: n n n n n n n n n n Also disclosed are a method of synthesizing the compound and use of the compound for treating various diseases and conditions.

专利号:US-11020399-B2
优先权日:2011-05-04
标 题:Intermediates useful in the synthesis of compounds as modulators of protein kinases