CAS: 14907-27-8; H-D-Trp-Ome.Hcl

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22032-65-1 7524-52-9 5619-09-0

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CAS号5619-09-0 DL-色氨酸甲酯盐酸盐 | CAS号171489-59-1 (1R,3R)-1-(1,3-... | CAS号171596-27-3 12-表-他达拉非 | CAS号171596-36-4 去甲基他达那非 | CAS号171596-28-4 6-表-他达拉非 | CAS号171596-29-5 他达那非 | CAS号249921-19-5 阿拉莫林 | CAS号629652-72-8 ENT-他达拉非 | CAS号159634-94-3 N-[N-[(1,1-二甲基乙... | CAS号171596-41-1 (1R,3r)-1,2,3,4... | CAS号171596-42-2 methyl (1S,3R)-...

D-色氨酸置于iron(III) Nitrate Nonahydrate,氯化亚砜,氨,Sodium体系中,化学反应 40.0H,反应生成D-色氨酸甲酯盐酸盐
参考文献:A General And Enantioselective Approach To Pentoses: A Rapid Synthesis Of Psi-6130,The Nucleoside Core Of Sofosbuvir
标题:A General And Enantioselective Approach To Pentoses: A Rapid Synthesis Of Psi-6130,The Nucleoside Core Of Sofosbuvir
摘要:An Efficient Route Towards Biologically Relevant Pentose Derivatives Is Described. The De Novo Synthetic Strategy Features An Enantioselective Alpha-Oxidation Reaction Enabled By A Chiral Amine In Conjunction With Copper(II) Catalysis. A Subsequent Mukaiyama Aldol Coupling Allows For The Incorporation Of A Wide Array Of Modular Two-Carbon Fragments. Lactone Intermediates Accessed Via This Route Provide A Useful Platform For Elaboration,As Demonstrated By The Preparation Of A Variety Of C-Nucleosides And Fluorinated Pentoses. Finally,This Work Has Facilitated Expedient Syntheses Of Pharmaceutically Active Compounds Currently In Clinical Use.
Doi:10.1021/ja502205Q

专利信息

专利号:US-2022356139-A1
优先权日:2019-09-03
标 题:Synthesis of deuterated aldehydes
发明人：WANG WEI
权利人:ARIZONA BOARD OF REGENTS ON BEHALF OF ATHE UNIV OF ARIZONA
摘要:Described are methods for preparing a deuterated aldehyde using N-heterocyclic carbene catalysts in a solvent comprising D 2 O. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions without functionality manipulation.

专利号:US-2011105751-A1
优先权日:2008-03-31
标题:Conversion of tryptophan into beta-carboline derivatives
发明人：PIRC SAMO
权利人:LEAK PHARMACEUTICALS D D
摘要:The invention belongs in the field of organic chemistry and relates to a new shortened Pictet-Spengler type reaction for preparing isomerically pure β-carboline compounds useful for the synthesis of tadalafil.

专利号:US-9422321-B2
优先权日:2010-09-07
标题 :Pyrimidine nucleoside derivatives, synthesis methods and uses thereof for preparing anti-tumor and anti-virus medicaments
发明人：CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE
权利人:CHANG JUNBIAO; AN HAOYUN; YU XUEJUN; GUO XIAOHE; HIGH & NEW TECH RES CENTER HENAN ACAD OF SCIENCES; ZHENGZHOU GRANLEN PHARMATECH LTD; UNIV ZHENGZHOU
摘要:The present invention relates to the field of pharmacochemistry. Disclosed are fluorinated and azido-substituted pyrimidine nucleoside derivatives, particularly compounds of the formula shown below: n nAlso disclosed are methods of preparation and uses for these compounds. The compounds can be used for preparing medicaments for treating diseases such as tumors and viral infections, and can be used separately or in combination with other medicaments. The compounds also have effective activity against diseases such as tumors and viral infections, while having few side effects, and thus have potential application value.

专利号:EP-4332098-A1
优先权日:2022-08-31
标题:Chiral synthesis of nornicotine and nicotine

专利号:WO-2021045879-A1
优先权日:2019-09-03
标 题 :Synthesis of deuterated aldehydes

专利号:CN-106432237-B
优先权日:2016-09-06
标题 :Synthesis and application of a class of amidine compounds containing two chiral centers