专利号:WO-2020240266-A1 优先权日:2019-05-31 标题:New endoperoxide compounds, process for obtaining them and uses thereof for control of perkinsiosis in bivalves 发明人:CRISTIANO MARIA; CABRAL LÃ?LIA; LEITE RICARDO; LEAL JOSÉ 权利人:CCMAR CENTRO DE CIENCIAS DO MAR UNIV DO ALGARVE; INST GULBENKIAN DE CIENCIA 摘要:The present invention relates to new endoperoxide compounds and compositions, and to a process for producing them for prophylaxis and control of perkinsiosis in bivalves. Endoperoxide compounds with biological activity against Perkinsus olseni include 13 trioxolanes and 9 tetraoxanes. Protozoan parasites of the genus Perkinsus are known to infect several species of marine molluscs worldwide, like oysters, abalones, clams, scallops, pearl oysters, cockles or mussels. The present invention also describes the synthesis of these compounds, in particular of new endoperoxide compounds of the tetraoxane family. Compositions comprising endoperoxide compounds are useful for prophylaxis and control of perkinsiosis in bivalves. Therefore, the present invention also relates to a method of controlling perkinsiosis in bivalves. The present invention is in the domain of aquaculture, medicine, pharmaceuticals and biochemistry.
专利号:RU-2152927-C1 优先权日:1994-11-09 标 题 :Amino-derivatives, method of inhibition of synthesis of nitrogen oxide, method of selective inhibition of synthesis of nitrogen oxide produced by inducible no-synthase, method of decrease of nitrogen oxide level, pharmaceutical composition
专利号:US-12150934-B2 优先权日:2016-11-30 标 题 :Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases 发明人:SIDDIQUI ARSHAD M; CIBLAT STEPHANE; CONSTANTINEAU-FORGET LEA; GRAND-MAITRE CHANTAL; GUO XIANGYU; SRIVASTAVA SANJAY; SHIPPS GERALD W; COOPER ALAN B; OZA VIBHA; KOSTURA MATTHEW W; LUTHER MICHAEL; LEVINE JEDD 权利人:BANTAM PHARMACEUTICAL LLC 摘要:Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by “aâ€?, R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.
专利号:WO-2024071514-A1 优先权日:2022-09-28 标题:Reduced graphene oxide with improved antibacterial properties and production method therefor 发明人:KIM SOONGIL; PARK HOBUM; JUNG JAEGU 权利人:LG ELECTRONICS INC; IUCF HYU 摘要:A method for producing reduced graphene oxide of an embodiment includes: performing hydrothermal synthesis by additionally adding a maximum of 300 urea and a maximum of 7 hydrazine (N2H4) based on 1 graphene oxide (GO) in terms of an amount of the urea to the hydrazine (N2H4) added; and washing the synthesized nitrogen-doped reduced graphene oxide (N-rGO).
专利号:PE-20151714-A1 优先权日:2014-04-07 标 题 :SYNTHESIS PROCEDURE OF THE TETRANITROTETRAZOLATE DI AQUO SODIUM CUPRATE COMPLEX
专利号:KR-101328156-B1 优先权日:2012-06-29 标题 :Synthesis method of etching agent for printed circuit board and LCD semiconductor
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