CAS: 15673-00-4; 3,3-Dimethylbutan-1-Amine

该化合物是具有分子分子式C6H15N(以其分支链结构为特征)的主要脂性矿,该化合物通常用作有机合成的中间体,特别是在生产药品,农用化学品和特殊化学品方面,其严重阻力使矿体群体在反应上更加具有选择性,使其对催化工艺和结链形成具有价值;该化合物在普通有机溶剂中表现出中度的基本性和高溶性,便于其用于各种工业用途;在标准条件下保持稳定和定义明确的再活动特征有助于其在合成化学工作流程中的可靠性.

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上下游产品

CAS号926-04-5 Butanamide,3,3-... | CAS号1647-23-0 3,3-二甲基-1-溴丁烷 | CAS号15818-31-2 1H-Isoindole-1,... | CAS号7065-46-5 3,3-二甲基丁酰氯 | CAS号558-37-2 3,3-二甲基-1-丁烯 | CAS号594-60-5 2,3-二甲基-2-丁醇 | CAS号624-95-3 3,3-二甲基-1-丁醇 | CAS号13608-36-1 Propanal, 2,2-d... | CAS号136670-88-7 (9ci)-2-(2,2-二甲... | CAS号7509-78-6 Butanal, 3,3-di...

合成工艺路线路线简述

  • 合成目标产物 3,3-Dimethylbutylamine 主要起始原料 3,3-Dimethyl-1-Butene
  • (文献来源)合成步骤主要原料 3,3-Dimethyl-1-Butene
3,3-二甲基丁酰氯置于lithium Aluminium Tetrahydride,氨体系中,用 四氢呋喃 用作溶剂,化学反应 18.5H,反应生成3,3-二甲基丁胺
参考文献:A New Quadruply Bound Heterodimer Ddad.aada And Investigations Into The Association Process
标题:A New Quadruply Bound Heterodimer Ddad.aada And Investigations Into The Association Process
摘要:
Doi:10.1002/1099-0690(200212)2002:23<4054::Aid-Ejoc4054>3.0.Co;2-H

专利信息


专利号:WO-2016005407-A1
优先权日:2014-07-07
标 题:One-pot synthesis of squaramides
发明人:MÃ?RQUEZ LÓPEZ MARÃ?A EUGENIA; ALEGRE REQUENA JUAN VICENTE; PÉREZ HERRERA RAQUEL
权利人:UNIV ZARAGOZA; CONSEJO SUPERIOR INVESTIGACION
摘要:The present invention refers to the first one-pot synthesis of squaramides. The one-pot synthesis of squaramides described herein is an easy and straightforward procedure to obtain squaramide derivatives which saves energy, avoids time consuming purification steps, reduces costs and provides better yields as compared with those squaramides obtained through the traditional 'stop-and-go' approach. Moreover, the authors of the present invention herein demonstrate the efficiency of this one-pot process with the synthesis of three biologically active structures, improving in most of the cases the results of the previous stepwise syntheses.

专利号:WO-9931124-A1
优先权日:1997-12-12
标 题:Cholic acid-based scaffolds for multidimensional molecular presentation of peptides
发明人:HOEEG-JENSEN THOMAS
权利人:NOVO NORDISK AS; HOEEG JENSEN THOMAS
摘要:A solid phase method for the synthesis of a plurality of differently substituted cholic acid scaffolds with a wide variety of peptide chain, pseudo-peptide chain or peptoid chain substitutents, as leads or compounds of potential therapeutic interest. The substituted cholic acids are prepared by initial solution synthesis of a scaffold holding amino acids with 3 orthogonal protecting groups. Subsequent solid-phase synthesis provides the build-up of the target molecules, either as discretes or in mixture. The molecules may be screened on the resin or cleaved from the resin and then screened in solution. The method disclosed here provides an easy and fast access to highly diverse compounds, potential peptide mimetics and potential leads for compounds of therapeutic interest. The method is amenable to automatization.

专利号:US-8299139-B1
优先权日:2009-09-08
标 题:Process and reactor for synthesis of ultra-high molecular weight acrylic polymers
发明人:TARANEKAR PRASAD; SCHUMAN AUSTIN L; BANERJIE ASIS
权利人:TARANEKAR PRASAD; SCHUMAN AUSTIN L; BANERJIE ASIS; OVATION POLYMER TECHNOLOGY AND ENGINEERED MATERIALS INC
摘要:This invention relates to a process for producing high molecular weight (HMW) and ultra-high molecular weight (UHMW) acrylic polymers having unique polymer tacticity and exhibiting enhanced thermal and mechanical properties. This process comprises polymerizing ethylenically unsaturated monomer in the presence of a free radical initiator that results in a “living-like polymerâ€? utilizing a multi-step approach. In conducting the process of this invention the “living-like polymerâ€? is further dissolved in a liquid carrier, wherein the said liquid carrier is a reactive diluent that can be reacted subsequently by an addition polymerization process to create a block- or multi-block, copolymer or homopolymer. This process can be progressively repeated with the same or various different reactive diluents to generate desired architecture and molecular weight polymer(s) which can be used in further processing procedures to be manufactured directly into finished articles.

专利号:US-10772971-B2
优先权日:2017-06-22
标 题:Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates
发明人:GURIJALA VENU REDDY; BOLLU SATYANARAYAN REDDY; LEBLANC JACQUES; LOWINGER TIMOTHY B; MCGILLICUDDY DENNIS; YIN MAO; YURKOVETSKIY ALEKSANDR V
权利人:MERSANA THERAPEUTICS INC; MERSANA THERPEUTICS INC
摘要:The disclosure provides methods of synthesis of polymeric scaffolds, e.g., those useful for conjugating with a protein based recognition-molecule (PBRM) to form PBRM-polymer-drug conjugates, and PBRM-polymer-drug conjugates thereof. The methods according to the disclosure allow for large-scale preparation of polymeric scaffolds having a high purity. In some embodiments, the methods according to the disclosure also allow for the preparation of scaffolds and conjugates thereof in better yield than previously used methods for preparing same. Also disclosed are methods of purifying polymeric scaffolds.

专利号:US-12441677-B2
优先权日:2019-11-14
标 题 :One step synthesis for alkyl 2-fluoroacrylates
发明人:JIN QINGWU; WHITACRE MICHAEL
权利人:VIFOR INT LTD
摘要:A process is provided that results in an alkyl haloacrylate that is produced by reaction of a dialkyl or diaryl halomalonate with an aldehyde, preferably formalin or paraformaldehyde, and a base catalyst to produce an intermediate that is not isolated and is heated to produce the alkyl haloacrylate. This synthesis can be one pot, meaning it reacts in the same vessel and/or reaction mixture and does not require isolation of the intermediate, and provides an improved yield. In particular, a process is provided that results in an alkyl 2-fluoroacrylate.

专利号:US-2017246690-A1
优先权日:2014-06-20
标 题:Stabilizing agent-free metal nanoparticle synthesis and uses of metal nanoparticles synthesized therefrom
发明人:MURPHY RYAN J; DREYFUS REMI; HOUGH LAWRENCE ALAN; MALASSIS LUDIVINE; MURRAY CHRISTOPHER; DONNIO BERTRAND
权利人:RHODIA OPERATIONS; CENTRE NAT RECH SCIENT; UNIV PENNSYLVANIA
摘要:Described herein are methods of synthesizing metal nanoparticles and the metal nanoparticles synthesized therefrom. Further described in the present disclosure are methods of modifying the surfaces of metal nanoparticles and the metal nanoparticles modified thereby. Also described herein are uses of such metal nanoparticles.
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合成参考文献


摘要:Bagal, D. B.; Bhanage, B. M., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2018) 2, 382.
参考文献:10.1107/s1600536810040705
摘要:Liu J, Wei Z, Wei X, Zhang C. 2-Hydroxy-3-octyloxy-N,N,N-trimethylpropan-1-aminium bromide. Acta Crystallogr E Struct Rep Online. 2010 Oct 20;66(11):o2865. doi: 10.1107/s1600536810040705.
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