CAS: 586-38-9; 3-Methoxybenzoic Acid

上下游产品

CAS号6706-95-2 3,3-二甲氧基苯偶姻 | CAS号201230-82-2 carbon monoxide | CAS号2845-89-8 3-氯苯甲醚 | CAS号71-36-3 正丁醇 | CAS号99-06-9 3-羟基苯甲酸 | CAS号77-78-1 硫酸二甲酯 | CAS号2398-37-0 间溴苯甲醚 | CAS号124-38-9 二氧化碳 | CAS号6971-51-3 3-甲氧基苄醇 | CAS号591-31-1 3-甲氧基苯甲醛 | CAS号3168-59-0 2-甲基-5-甲氧基苯甲酸 | CAS号33234-36-5 2-氯-3-甲氧基苯甲酸 | CAS号54413-93-3 2-碘-5-甲氧基苯甲酸 | CAS号56256-14-5 4-溴-3-甲氧基苯甲酸 | CAS号4920-80-3 3-甲氧基-2-硝基苯甲酸 | CAS号5081-36-7 3-甲氧基-4-硝基苯甲酸 | CAS号4771-80-6 3-环己烯-1-甲酸 | CAS号40101-17-5 3,3'-二甲氧基苯偶酰 | CAS号36132-95-3 (4-甲氧基-1,2-亚苯基)二甲醇 | CAS号90047-52-2 [2-(hydroxymeth...

间羟基苯甲酸置于potassium Carbonate,Potassium Iodide,Sodium Hydroxide体系中,用 甲醇,水 作为反应溶剂,化学反应 15.0H,反应生成 3-甲氧基苯甲酸
参考文献:靶向肿瘤沃伯格效应的肿瘤诊断和治疗荧光探针
标题:靶向肿瘤沃伯格效应的肿瘤诊断和治疗荧光探针
摘要:本发明公开了靶向肿瘤沃伯格效应的肿瘤诊断和治疗荧光探针,其荧光探针的结构如式(I)所示:本发明的荧光探针能够直接用在细胞系中分析和检测肿瘤细胞glut1蛋白的表达程度,从而完成对肿瘤细胞的筛选.同时通过直接阻断glut1通道抑制肿瘤对糖营养成分的摄取抑制肿瘤细胞增殖.为肿瘤早期筛选和诊断,开发新的抗肿瘤药物等提供了有效的手段和有用的工具.

专利信息

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-2002192767-A1
优先权日:1999-10-13
标题 :Biosynthesis of polyketide synthase substrates
发明人：KHOSLA CHAITAN; PFEIFER BLAINE
摘要:The use of enzymes which catalyze the production of starter and extender units for polyketides is described. In addition, modified loading modules are described, which can accept a variety of starting units such as substituted benzoates, and which can be used to generate substituted derivatives of natural products. These enzymes may be used to enhance the yield of polyketides that are natively produced or polyketides that are rationally designed. By using these techniques, the synthesis of a complete polyketide has been achieved in E. coli . Production can be enhanced in microbial organisms of polyketides and other secondary metabolites by delaying production until after exponential phase and by maintaining relatively constant nutrient levels in the medium. In addition, polyketide production can be enhanced by providing an expression system for a thioesterase II. Thus, by modifying the host organism and changing the culture conditions, synthesis of a secondary metabolite can be enhanced. The present invention also results in a host organism with desirable characteristics to be used in the production of such polyketides and to assess the results of gene shuffling.

专利号:WO-02068613-A1
优先权日:2001-02-28
标题 :Biosynthesis of polyketide synthase substrates
发明人：KHOSLA CHAITAN; PFEIFER BLAINE
权利人:UNIV LELAND STANFORD JUNIOR; KHOSLA CHAITAN; PFEIFER BLAINE
摘要:The use of enzymes which catalyze the production of starter and extender units for polyketides is described. In addition, modified loading modules are described, which can accept a variety of starting units such as substituted benzoates, and which can be used to generate substituted derivatives of natural products. These enzymes may be used to enhance the yield of polyketides that are natively produced or polyketides that are rationally designed. By using these techniques, the synthesis of a complete polyketide has been achieved in E. coli. Production can be enhanced in microbial organisms of polyketides and other secondary metabolites by delaying production until after exponential phase and by maintaining relatively constant nutrient levels in the medium. In addition, polyketide production can be enhanced by providing an expression system for a thioesterase II. Thus, by modifying the host organism and changing the culture conditions, synthesis of a secondary metabolite can be enhanced. The present invention also results in a host organism with desirable characteristics to be used in the production of such polyketides and to assess the results of gene shuffling.

专利号:US-4405523-A
优先权日:1982-03-24
标题:Process for preparation of benzophenone, anthraquinone and O-dibenzoylbenzene
发明人：FIELDS ELLIS K
权利人:STANDARD OIL CO INDIANA
摘要:Process for the concurrent synthesis of benzophenone, anthraquinone, and o-dibenzoylbenzene by pyrolysis of benzoic acid salts of yttrium, erbium, and dysprosium and mixtures thereof at temperatures of from about 200 DEG C. to 500 DEG C. and a pressure of about 0.1 to about 100 atmospheres. In an alternative method, a benzoic acid compound is passed through an oxide of yttrium, erbium, dysprosium and mixtures thereof in the presence of steam.

专利号:US-2002045220-A1
优先权日:1999-10-13
标题:Biosynthesis of polyketide synthase substrates
发明人：KHOSLA CHAITAN; PFEIFER BLAINE
摘要:The use of enzymes which catalyze the production of starter and extender units for polyketides is described. In addition, modified loading modules are described, which can accept a variety of starting units such as substituted benzoates, and which can be used to generate substituted derivatives of natural products. These enzymes may be used to enhance the yield of polyketides that are natively produced or polyketides that are rationally designed. By using these techniques, the synthesis of a complete polyketide has been achieved in E. col. This achievement permits a host organism with desirable characteristics to be used in the production of such polyketides and to assess the results of gene shuffling.

专利号:US-9050586-B2
优先权日:2012-03-13
标 题:Enantioselective organic anhydride reactions
发明人：CONNON STEPHEN J; TALLON SEAN; CORNAGGIA CLAUDIO; MANONI FRANCESCO; TORRENTE ESTHER
权利人:CONNON STEPHEN J; TALLON SEAN; CORNAGGIA CLAUDIO; MANONI FRANCESCO; TORRENTE ESTHER; PROVOST FELLOWS & SCHOLARS COLLEGE OF THE HOLY UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
摘要:Disclosed herein is enantioselective synthetic method comprising reacting an enolisable C 4 -C 50 organic anhydride with a second compound selected from the group consisting of an aldehyde, a ketone, an aldimine, a ketimine or a Michael Acceptor in the presence of a bifunctional organocatalyst. The reaction may find particular utility in the enantioselective synthesis of medicinally relevant heterocycles, such as dihydroisocoumarins and dihydroisoquinolinones.