CAS: 942-92-7; Hexanophenone

上下游产品

pyridine bis-(1-phenyl-cyclohexyl)-peroxide 1-bromo-butane α-methoxystyrene2-hydroxy-2-phenyl-heptanoic acid amide 2-phenylheptane-2-ol 1-phenyl-2-piperidinomethyl-hexan-1-one; hydr°Chloride (E)-1-phenyl-1,2-hexanedione 2-oxime

己酸置于4-二甲氨基吡啶,1,10-邻菲啰啉二溴化镍,二氢吡啶,N,N'-二环己基碳二亚胺,Lithium Bromide体系中,用 四氢呋喃,N,N-二甲基乙酰胺 作为反应溶剂,化学反应 48.0H,反应生成 苯己酮
参考文献:用于酮合成的镍介导的羧酸衍生物光还原交叉偶联**
标题:用于酮合成的镍介导的羧酸衍生物光还原交叉偶联**
摘要:介导合成:提出了一种使用可见光和两种羧酸衍生底物镍催化合成酮的策略.不需要昂贵的铱催化剂,环保的 Hantzsch 酯既充当光敏剂又充当光还原剂.介绍了广泛的合成酮以及不同反应物作用的光谱和计算研究.
DOI:10.1002/chem.202103486

专利信息

专利号:US-6066705-A
优先权日:1995-08-31
标 题 :Vapor phase synthesis of cis-1, 4-Polyisoprene
发明人：CALDERON NISSIM; CASTNER KENNETH FLOYD; COLVIN HOWARD ALLEN; MUSE JR JOEL
权利人:GOODYEAR TIRE & RUBBER
摘要:By utilizing the vapor phase polymerization techniques of the present invention, numerous distinct and highly beneficial advantages are realized. For instance, cis-1,4-polyisoprene rubber and high cis-1,4-polybutadiene rubber having a consistent and controllable molecular weight can be easily and practically prepared without utilizing a solvent. The subject invention more specifically discloses a method for vapor phase polymerizing isoprene into cis-1,4-polyisoprene in a process comprising the steps of: (1) charging into a reaction zone said isoprene and a preformed catalyst system which is made by reacting an organoaluminum compound with titanium tetrachloride, preferably in the presence of at least one ether; wherein the isoprene is maintained in the vapor phase in said reaction zone by a suitable combination of temperature and pressure; (2) allowing said isoprene to polymerize into cis-1,4-polyisoprene at a temperature within the range of about 35 DEG C. to about 70 DEG C.; and (3) withdrawing said cis-1,4-polyisoprene from said reaction zone. It has been determined that gel formation can be reduced by conducting the polymerization of isoprene monomer in the presence of a diarylamine, such as para-styrenated diphenylamine.

专利号:US-5859156-A
优先权日:1995-08-31
标 题 :Vapor phase synthesis of rubbery polymers
发明人：CALDERON NISSIM; MUSE JR JOEL; COLVIN HOWARD ALLEN; CASTNER KENNETH FLOYD
权利人:GOODYEAR TIRE & RUBBER
摘要:By utilizing the vapor phase polymerization techniques of the present invention, numerous distinct and highly beneficial advantages are realized. For instance, cis-1,4-polyisoprene rubber and high cis-1,4-polybutadiene rubber having a consistent and controllable molecular weight can be easily and practically prepared without utilizing a solvent. The subject invention more specifically discloses a method for vapor phase polymerizing isoprene into cis-1,4-polyisoprene in a process comprising the steps of: (1) charging into a reaction zone said isoprene and a preformed catalyst system which is made by reacting an organoaluminum compound with titanium tetrachloride, preferably in the presence of at least one ether; wherein the isoprene is maintained in the vapor phase in said reaction zone by a suitable combination of temperature and pressure; (2) allowing said isoprene to polymerize into cis-1,4-polyisoprene in said reaction zone at a temperature within the range of about 0 DEG C. to about 100 DEG C. in the presence of a diarylamine, wherein said reaction zone is a horizontal, stirred reactor of substantially circular cross section containing a centrally-located drive shaft extending longitudinally through said reactor to which are attached a plurality of adjacently located paddles, which paddles cause essentially no forward or backward movement of the cis-1,4-polyisoprene contained in said reactor; and (3) withdrawing said cis-1,4-polyisoprene from said reaction zone.

专利号:US-3883591-A
优先权日:1969-02-26
标 题:Intermediates for the preparation of 1,3-dihydro-2H-1,4-benzodiazepin-2-ones
发明人：MCCAULLY RONALD J
权利人:AMERICAN HOME PROD
摘要:Two routes for the preparation of 2-(2-acylamido-2-amino)acetamidophenyl aryl ketones, used as intermediates in the synthesis of psycholeptic 1,3-dihydro-2H-1,4-benzodiazepin-2-ones are described. The first of these routes involves the formation of a 2-(2,2-diacyloxy)acetamidophenyl aryl ketone from glyoxylic acid and an aryl phenyl ketone via either a 2,2-diacyloxy acetyl halide or a 2,2-diacyloxy acetyl anhydride, coversion thereof to the corresponding 2-(2-acylamido-2-hydroxy) acetamidophenyl aryl ketone directly or via the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone, formation of the corresponding 2-(2-acylamido-2halo)acetamidophenyl aryl ketone, and conversion to the 2-(2acylamido-2-amino)acetamidophenyl aryl ketone. The second route forms the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone by reacting a 2,3-dicarboxylicacyl tartaric anhydride with a 2aminophenyl aryl ketone to obtain a 2-(3-carboxy-2,3acyloxy)propionamidophenyl aryl ketone, selectively hydrolyzing the so-obtained ketone and selectively oxidizing the product with a vic glycol cleaving agent.

专利号:US-7081504-B2
优先权日:2004-08-30
标 题:Synthesis of 1,4-polybutadiene
发明人：RACHITA MICHAEL JOSEPH; JOHNSON SCOTT EDWARDS
权利人:GOODYEAR TIRE & RUBBER
摘要:This invention is based upon the unexpected discovery that alkylated diphenylamines can be used in conjunction with nickel based catalyst systems which contain (a) an organonickel compound, (b) an organoaluminum compound, and (c) a fluorine containing compound to produce cis-1,4-polybutadiene having reduced molecular weight and an increased level of branching. This results in the cis-1,4-polybutadiene exhibiting good processability without sacrificing cold flow characteristics. Additionally, the alkylated diphenylamine which remains in the rubber acts in a manner which provides it with antioxidant protection. In other words, the use of alkylated diphenylamines accomplishes the three major objectives that are realized by employing para-styrenated diphenylamines (reduced molecular weight, regulated polymer macrostructure through branching and antidegradant protection). However, the utilization of alkylated diphenylamines, unlike para-styrenated diphenylamines, offers the additional advantage of being soluble in aliphatic solvents. By virtue of this increased level of solubility in aliphatic solvents, such as hexane, alkylated diphenylamines can be employed at greatly reduced levels of aromatic solvents. Likewise, when mixed catalyst streams containing alkylated diphenyl amines are combined precipitation is minimized compared to para-styrenated diphenylamine significantly improving issues related to fouling. The subject invention more specifically discloses a process for producing cis-1,4-polybutadiene having a reduced molecular weight and improved processability which comprises polymerizing 1,3-butadiene in the presence of (a) an organonickel compound, (b) an organoaluminum compound, (c) a fluorine containing compound, and (d) an alkylated diphenylamine; wherein the alkylated diphenylamine has alkyl groups that contain from 2 to 18 carbon atoms, and wherein the organoaluminum compound and the fluorine containing compound are brought together in the presence of the alkylated diphenylamine.

专利号:US-3899527-A
优先权日:1969-02-26
标题:Intermediates for the preparation of 1,3-dihydro-2H-1,4-benzodiazepin-2-ones
发明人：MCCAULLY RONALD J
权利人:AMERICAN HOME PROD
摘要:Two routes for the preparation of 2-(2-acylamido-2-amino)acetamidophenyl aryl ketones, used as intermediates in the synthesis of psycholeptic 1,3-dihydro-2H-1,4-benzodiazepin-2-ones are described. The first of these routes involves the formation of a 2-(2,2-diacyloxy)acetamidophenyl aryl ketone from glyoxylic acid and an aryl phenyl ketone via either a 2,2-diacyloxy acetyl halide or a 2,2-diacyloxy acetyl anhydride, conversion thereof to the corresponding 2-(2-acylamido-2-hydroxy) acetamidophenyl aryl ketone directly or via the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone, formation of the corresponding 2-(2-acylamido-2halo)acetamidophenyl aryl ketone, and conversion to the 2-(2acylamido-2-amino)acetamidophenyl aryl ketone. The second route forms the 2-(2,2-dihydroxy)acetamidophenyl aryl ketone by reacting a 2,3-dicarboxylicacyl tartaric anhydride with a 2aminophenyl aryl ketone to obtain a 2-(3-carboxy-2,3acyloxy)propionamidophenyl aryl ketone, selectively hydrolyzing the so-obtained ketone and selectively oxidizing the product with a vic glycol cleaving agent.

专利号:US-7517828-B2
优先权日:2003-04-25
标 题 :Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst
发明人：AKIYAMA TAKAHIKO
权利人:TOAGOSEI CO LTD
摘要:A compound usable as an asymmetric synthesis catalyst which can be easily synthesized without using any metal such as a lanthanoid group element; a method of asymmetric synthesis with the compound; and a chiral compound obtained by the asymmetric synthesis method. A Broensted acid is used as a catalyst in asymmetric synthesis, the chiral Broensted acid being represented by formula (1) below or formula (3) below. The asymmetric synthesis method employs the catalyst. Asymmetric synthesis with the catalyst gives a chiral compound.